Patent US5008078A successfully refreshed from Google Patents.
US5008078A
Expired / Lapsed
US
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Integral multi-layer analysis element
Assignee: Fujifilm Holdings Corp
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Filing: 1988-04-18
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Granted: 1991-04-16
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Expires: 2008-04-18
Abstract
Abstract A multi-layer analysis element including an endogenous ammonia trapping layer, an ammonia producing layer containing a composition capable of reacting with an ammonia producing substance to produce gaseous ammonia, and at least one layer essentially incapable of trapping ammonia and essentially incapable of producing ammonia, and capable of preventing the diffusion of ammonia, disposed between the endogenous ammonia trapping layer and the ammonia producing layer. The unified multi-layer analysis element according to the invention is useful for the quantitative analysis of ammonia producing substances in aqueous biological food samples, with a high degree of sensitivity and accuracy, using a simple procedure.
Inventors
- 👤 Nakatsugu Yaginuma
- 👤 Takaki Arai
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 08:40
CPC Classifications
C; C12; C12Q; C12Q1/00; G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/52; G01N33/525; G01N33/526; Y; Y10; Y10T; Y10T436/00; Y10T436/17; Y10T436/173845; Y10T436/175383
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
66 words
A multi-layer analysis element comprising an endogenous ammonia trapping layer, an ammonia producing layer comprising a reagent capable of reacting with an ammonia producing substance to produce gaseous ammonia, and at least one layer essentially incapable of trapping ammonia and essentially incapable of producing ammonia and capable of preventing the diffusion of gaseous ammonia, disposed between said endogenous ammonia trapping layer and said ammonia producing layer.
Claim 2
Dependent Claim
66 words
A multi-layer analysis element comprising an endogenous ammonia trapping layer, an ammonia producing layer comprising a reagent capable of reacting with an ammonia producing substance to produce gaseous ammonia, and at least one layer essentially incapable of trapping ammonia and essentially incapable of producing ammonia and capable of preventing the diffusion of gaseous ammonia, disposed between said endogenous ammonia trapping layer and said ammonia producing layer.
Claim 3
Dependent Claim
28 words
A multi-layer analysis element as claimed in claim 1 wherein the thickness of said layer capable of preventing the diffusion of ammonia is at least about 5 μm.
Claim 4
Dependent Claim
86 words
A multi-layer analysis element as claimed in claim 1 comprising an optically transparent and water impermeable support having thereon in the following order outwardly from said support: (1) An ammonia indicator layer comprising indicator capable of undergoing detectable change produced by gaseous ammonia; (2) A liquid permeation barrier layer permeable to gaseous ammonia; (3) Said ammonia producing layer; (4) Said layer capable of preventing the diffusion of ammonia; (5) Said endogenous ammonia trapping layer, wherein said endogenous ammonia trapping layer is also a porous spreading layer.
Claim 5
Dependent Claim
83 words
A multi-layer analysis element as claimed in claim 1 comprising an optically transparent and water impermeable support having thereon in the following order outwardly from said support: (1) An ammonia indicator layer comprising an indicator capable of undergoing a detectable change produced by gaseous ammonia; (2) A liquid permeation barrier layer permeable to gaseous ammonia; (3) Said ammonia producing layer; (4) Said layer capable of preventing the diffusion of gaseous ammonia; (5) Said endogenous ammonia trapping layer; and (6) a porous spreading layer.
Claim 6
Dependent Claim
26 words
The multi-layer analysis element as claimed in claim 4, wherein said liquid permeation barrier layer is a porous air barrier layer or a polymer barrier layer.
Claim 7
Dependent Claim
57 words
The multi-layer analysis element as claimed in claim 4, wherein said layer capable of preventing the diffusion of ammonia comprises from about 4.0 g/m 2 to 40 g/m 2 of an essentially non-porous, polymer binder, said layer having a thickness of from about 5 μm to 50 μm and a pH of from about 7.0 to 11.0.
Claim 8
Dependent Claim
64 words
The multi-layer analysis element as claimed in claim 4, wherein said layer capable of preventing the diffusion of ammonia comprises from about 5.5 g/m 2 to 25 g/m 2 of a hydrophilic polymer binder selected from a gelatin and a gelatin derivative, said layer having a pH of from about 8.0 to 10.0 and a thickness of from about 7 μm to 30 μm.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1994-04-15 | 1994-10-15 | 1995-04-16 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1998-04-15 | 1998-10-15 | 1999-04-16 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2002-04-15 | 2002-10-15 | 2003-04-16 | $7700.00 | Window Closed / Lapsed |