US4818539A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Ingestible aggregate and delivery system prepared therefrom
Assignee: Warner Lambert Co LLC
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Filing: 1988-02-29
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Granted: 1989-04-04
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Expires: 2008-02-29
Abstract
Abstract The present invention relates to an ingestible aggregate comprising a pre-swelled substantially anhydrous hydrocolloid and a substrate. More particularly this invention relates to an aggregate having as a substrate a dietary fiber and/or drug wherein the composition can be administered in a therapeutically effective amount. Hydrocolloids useful include natural and modified gums, celluloses, modified celluloses, pectins, mucillages, modified starches, noncellulose polysaccharides, algal polysaccharides and mixtures thereof. The aggregate should be in the size range of about 4 to about 70 U.S. mesh. The unpleasant taste and mouthfeel of the fiber and/or drug is effectively masked and substantial hydration is delayed until the composition reaches the stomach. The compositions are substantially more palatable, devoid of graininess, bitterness or fibrous texture. The pleasant taste of the composition encourages patient compliance with their fiber or drug therapy.
Inventors
- 👤 James J. Shaw
- 👤 Shri C. Sharma
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 08:01
CPC Classifications
A; A23; A23G; A23G3/00; A23G3/34; A23G3/36; A23G3/364; A23G3/368; A23L; A23L33/00; A23L33/20; A23L33/21; A61; A61K; A61K9/00; A61K9/0012; A61K9/0053; A61K9/0056; A61K9/14; A61K9/16; A61K9/1605; A61K9/1629; A61K9/1652; A61K9/48; A61K9/50; A61K9/5005; A61K9/5021; A61K9/5036; A61K9/5042; A61K9/5047; A61K9/5073
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
106 words
A delivery system comprising (i) an edible matrix; and (ii) an ingestible substantially anhydrous aggregate having a particle size of about 4 to about 80 mesh, U.S. Std. Sieve and having a density of about 0.25 g/cc, consisting essentially of a pre-swelled hydrocolloid and a substrate, wherein the hydrocolloid in its hydrated form is applied to the substrate under pressure of about 1 to about 5 bar, wherein the hydrocolloid at least partially entraps and binds the substrate, wherein the substrate is selected from the group consisting of dietary fibers, drugs and mixtures thereof, and wherein the substrate and the hydrocolloid are not the identical material.
Claim 2
Dependent Claim
106 words
A delivery system comprising (i) an edible matrix; and (ii) an ingestible substantially anhydrous aggregate having a particle size of about 4 to about 80 mesh, U.S. Std. Sieve and having a density of about 0.25 g/cc, consisting essentially of a pre-swelled hydrocolloid and a substrate, wherein the hydrocolloid in its hydrated form is applied to the substrate under pressure of about 1 to about 5 bar, wherein the hydrocolloid at least partially entraps and binds the substrate, wherein the substrate is selected from the group consisting of dietary fibers, drugs and mixtures thereof, and wherein the substrate and the hydrocolloid are not the identical material.
Claim 3
Dependent Claim
14 words
The delivery system of claim 1 wherein the edible matrix is a confectionery composition.
Claim 4
Dependent Claim
26 words
The delivery system of claim 1 wherein the edible matrix is present in amounts of about 50% to about 99.9% by weight of the delivery system.
Claim 5
Dependent Claim
22 words
The delivery system of claim 1 wherein the ratio of the hydrocolloid to the substrate is from about 3:1 to about 20:1.
Claim 6
Dependent Claim
18 words
The delivery system of claim 1 wherein the edible matrix comprises hydrogenated vegetable oil, chocolate and cocoa butter.
Claim 7
Dependent Claim
15 words
The delivery system of claim 1 wherein the edible matrix is a gel or nougat.
Claim 8
Dependent Claim
13 words
The delivery system of claim 1 wherein the edible matrix is boiled candy.
Claim 9
Dependent Claim
13 words
The delivery system of claim 1 wherein the edible matrix is a liquid.
Claim 10
Dependent Claim
33 words
The delivery system of claim 1 wherein the hydrocolloid is selected from the group consisting of natural and modified gums, celluloses and modified celluloses, pectin, mucillages, modified starches, noncellulosic polysaccharides and mixtures thereof.
Claim 11
Dependent Claim
29 words
The delivery system of claim 9 wherein the hydrocolloid is selected from the group consisting of carboxymethyl cellulose, methyl cellulose, karaya gum, sodium alginate, calcium alginate, and mixtures thereof.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-04-03 | 1992-10-03 | 1993-04-04 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-04-03 | 1996-10-03 | 1997-04-04 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-04-03 | 2000-10-03 | 2001-04-04 | $7700.00 | Window Closed / Lapsed |