GB1573487A
Expired / Lapsed
GB
⏱️ 0.0 years remaining
Bile acid binding composition
Assignee: Bristol Myers Co
•
Filing: 1978-05-08
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Granted: —
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Expires: 1998-05-08
Abstract
No abstract record available.
Inventors
No inventors recorded.
Bibliographic Details
Application Number
—
Jurisdiction
GB
Data Source
google_patents
Last Synchronized
2026-10-23 12:46
CPC Classifications
A; A61; A61K; A61K33/00; A61K33/06; A61K33/10; A61P; A61P3/00; A61P3/12; A61P3/14
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
79 words
A bile acid binding composition in unit dosage form effective upon oral administration for the purpose of increasing bile acid excretion which comprises from 1.2 to 6 g. of calcium carbonate and from 6 to 20 g. of a polymeric, water-insoluble, non-toxic styrenedivinylbenzene quaternary ammonium anion exchange resin having a molecular weight in excess of 3,000, a polymer skeleton inert to digestive enzymes, and a water content greater than 65 wt% after equilibration with air at 100% relative humidity.
Claim 2
Dependent Claim
79 words
A bile acid binding composition in unit dosage form effective upon oral administration for the purpose of increasing bile acid excretion which comprises from 1.2 to 6 g. of calcium carbonate and from 6 to 20 g. of a polymeric, water-insoluble, non-toxic styrenedivinylbenzene quaternary ammonium anion exchange resin having a molecular weight in excess of 3,000, a polymer skeleton inert to digestive enzymes, and a water content greater than 65 wt% after equilibration with air at 100% relative humidity.
Claim 3
Dependent Claim
22 words
A composition as claimed in claim 1 wherein the polymer is a quaternary ammonium anion exchange resin with less than 5% cross-linkage.
Claim 4
Dependent Claim
20 words
A composition as claimed in claim 2 wherein the polymer is a quaternary ammonium anion exchange resin with 2% cross-linkage.
Claim 5
Dependent Claim
17 words
A composition as claimed in any one of the preceding claims wherein the polymer is cholestyramine .
Claim 6
Dependent Claim
14 words
A composition as claimed in claim 4 wherein said polymer is pharmaceutical grade cholestyramine.
Claim 7
Dependent Claim
15 words
A composition as claimed in claim 4 wherein said polymer is cholestyramine in beadlet form.
Claim 8
Dependent Claim
22 words
A composition as claimed in claim 6 wherein the beadlets have a diameter in the range of from 150 to 900 microns.
Claim 9
Dependent Claim
22 words
A composition as claimed in claim 7 wherein the beadlets have a diameter in the range of from 300 to 850 microns.
Claim 10
Dependent Claim
23 words
A composition as claimed in any one of the preceding claims which comprises 12 g. of cholestyramine and 5.6 g. of calcium carbonate.
Claim 11
Dependent Claim
31 words
A composition as claimed in any one of claims 1 to 4 or 5 to 8 which comprises 8 g. of cholestyramine in beadlet form and 2 g. of calcium carbonate.
Claim 12
Dependent Claim
18 words
A composition as claimed in any one of the preceding claims which includes therein a pharmaceutically acceptable carrier.
Claim 13
Dependent Claim
25 words
A composition as claimed in any one of the preceding claims which is in the form of tablets, an elixir, a syrup or a suspension.
Claim 14
Dependent Claim
17 words
A composition as claimed in claim 1 substantially as hereinbefore described with reference to the foregoing Examples.
References Cited (Backward Citations)
No citation records indexed.
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