US4632980A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Ozone decontamination of blood and blood products
Assignee: IMMUNOLOGICS, LIMITED PARTNERSHIP C/O MCMICKING & CO. 25 ECKER STREET, SUITE 800, SAN FRANCISCO, CA 95105
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Filing: 1985-04-03
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Granted: 1986-12-30
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Expires: 2005-04-03
Abstract
Abstract Blood and proteinaceous blood products employed for their physiological and/or immunological properties are free of viable enveloped viruses by treatment with low levels of ozone, levels at which substantially all of the physiological and/or immunological activity is retained.
Inventors
- 👤 Yuan C. Zee
- 👤 David C. Bolton
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-30 14:07
CPC Classifications
A; A61; A61L; A61L2/00; A61L2/16; A61L2/20; A61L2/202; A61L2103/00; A61L2103/05; A61M; A61M1/00; A61M1/14; A61M1/16; A61M1/1698; A61M1/32; A61M2202/00; A61M2202/02; A61M2202/0216; Y; Y10; Y10S; Y10S530/00; Y10S530/827; Y10S530/829; Y10S530/83
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
69 words
A method for freeing blood and blood components of viable enveloped viruses while retaining the physiological characteristics of the blood or blood component, said method comprising: contacting said blood or blood product in an aqueous medium with an enveloped virus inactivating amount of ozone under mild conditions for a sufficient time to inactivate all enveloped viruses present; and isolating the blood or blood component free of viable enveloped viruses.
Claim 2
Independent Claim
69 words
A method for freeing blood and blood components of viable enveloped viruses while retaining the physiological characteristics of the blood or blood component, said method comprising: contacting said blood or blood product in an aqueous medium with an enveloped virus inactivating amount of ozone under mild conditions for a sufficient time to inactivate all enveloped viruses present; and isolating the blood or blood component free of viable enveloped viruses.
Claim 3
Dependent Claim
31 words
A method according to claim 1, wherein said contacting is at a temperature in the range of 4° to 37° C. and at an ozone concentration of 1 to 100 ppm.
Claim 4
Dependent Claim
18 words
A method according to claim 2, wherein said blood or blood component is contacted as a thin film.
Claim 5
Dependent Claim
19 words
A method according to claim 2, wherein the contacting is for a duration of 0.5 hr to 4 days.
Claim 6
Dependent Claim
12 words
A method according to claim 2, wherein blood is contacted with ozone.
Claim 7
Dependent Claim
18 words
A method according to claim 2, wherein an aqueous solution of a blood component is contacted with ozone.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1989-12-29 | 1990-06-30 | 1990-12-30 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1993-12-29 | 1994-06-30 | 1994-12-30 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1997-12-29 | 1998-06-30 | 1998-12-30 | $7700.00 | Window Closed / Lapsed |