US4575495A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Synthetic antigenic peptide derived from Hepatitis B surface antigen
Assignee: New York Blood Center
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Filing: 1984-07-17
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Granted: 1986-03-11
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Expires: 2004-07-17
Abstract
Abstract There is disclosed a new synthetic peptide which evokes an immunological response. The synthetic peptide, moreover, interacts with antibodies to Hepatitis B surface antigen (HBsAG). Thus, the synthetic peptide is useful as an immunizing agent in a vaccine as an active component thereof where it serves to produce antibodies in vivo which are protective against Hepatitis B virus. The synthetic peptide of the invention comprises the following sequence of amino acids: Arg Trp Met Met Leu Arg Arg(I) and preferably has the following sequence: Gly Tyr Arg Trp Met Met Leu Arg Arg Phe Gly (II).
Inventors
- 👤 John Vnek
- 👤 Alfred M. Prince
- 👤 Hafeez Ikram
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-04 10:01
CPC Classifications
C; C07; C07K; C07K14/00; C07K14/005; A; A61; A61K; A61K39/00; C12; C12N; C12N2730/00; C12N2730/00011; C12N2730/10011; C12N2730/10111; C12N2730/10122; Y; Y10; Y10S; Y10S930/00; Y10S930/01; Y10S930/22; Y10S930/223
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
28 words
A synthetic peptide consisting essentially of the following sequence of amino acids Arg Trp Met Met Leu Arg Arg (I) wherein said peptide is disposed on a carrier.
Claim 2
Dependent Claim
28 words
A synthetic peptide consisting essentially of the following sequence of amino acids Arg Trp Met Met Leu Arg Arg (I) wherein said peptide is disposed on a carrier.
Claim 3
Dependent Claim
15 words
A synthetic peptide according to claim 1, wherein said carrier is a physiologically acceptable carrier.
Claim 4
Dependent Claim
13 words
A synthetic peptide according to claim 2, wherein said carrier comprises tetanus toxoid.
Claim 5
Dependent Claim
13 words
A synthetic peptide according to claim 1, wherein said carrier comprises polyethylene glycol.
References Cited (Backward Citations)
US4428941A
Cited
US4493796A
Cited
EP0056249A2
Cited
US4499080A
Cited
US4499081A
Cited
US4496521A
Cited
US4493795A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1989-03-10 | 1989-09-09 | 1990-03-11 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1993-03-10 | 1993-09-09 | 1994-03-11 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1997-03-10 | 1997-09-09 | 1998-03-11 | $7700.00 | Window Closed / Lapsed |