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US4568540A
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Oral hygiene compositions
Assignee: Johnson and Johnson
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Filing: 1984-04-18
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Granted: 1986-02-04
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Expires: 2004-04-18
Abstract
Abstract An oral hygiene composition containing an effective concentration of a pharmaceutically acceptable fluoride salt, a pharmaceutically acceptable zinc salt, a specific buffering agent, a suitable vehicle and having a pH of from about 3.5 to 6.0.
Inventors
- 👤 Akira Asano
- 👤 Maria C. Gaffar
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-04 10:33
CPC Classifications
A; A61; A61K; A61K8/00; A61K8/18; A61K8/19; A61K8/20; A61K8/27; A61K8/21; A61K8/30; A61K8/33; A61K8/36; A61K8/365; A61Q; A61Q11/00; A61K2800/00; A61K2800/40; A61K2800/52
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
111 words
An oral hygiene composition consisting essentially of an effective concentration of a pharmaceutically acceptable fluoride salt selected from the group consisting of sodium fluoride, potassium fluoride, lithium fluoride, aluminum fluoride, zinc fluoride, stannous fluoride, sodium monofluorophosphate, acidulated phosphate fluoride, ammonium fluoride, ammonium bifluoride, titanium tetrafluoride and amine fluoride, a pharmaceutically acceptable zinc salt selected from the group consisting of zinc chloride, zinc sulfate and zinc thiocyanate, a buffering agent selected from the group consisting of sodium gluconate, maleic acid, aspartic acid, gluconic acid, succinic acid, glucuronic acid, glucuronic acid lactone, fumaric acid and sodium glutamate and a suitable oral hygiene vehicle and having a pH of from about 3.5 to 6.0.
Claim 2
Dependent Claim
111 words
An oral hygiene composition consisting essentially of an effective concentration of a pharmaceutically acceptable fluoride salt selected from the group consisting of sodium fluoride, potassium fluoride, lithium fluoride, aluminum fluoride, zinc fluoride, stannous fluoride, sodium monofluorophosphate, acidulated phosphate fluoride, ammonium fluoride, ammonium bifluoride, titanium tetrafluoride and amine fluoride, a pharmaceutically acceptable zinc salt selected from the group consisting of zinc chloride, zinc sulfate and zinc thiocyanate, a buffering agent selected from the group consisting of sodium gluconate, maleic acid, aspartic acid, gluconic acid, succinic acid, glucuronic acid, glucuronic acid lactone, fumaric acid and sodium glutamate and a suitable oral hygiene vehicle and having a pH of from about 3.5 to 6.0.
Claim 3
Dependent Claim
23 words
The composition of claim 1 wherein the fluoride ion is present in a concentration of from about 0.0025 to about 4.0% by weight.
Claim 4
Dependent Claim
23 words
The composition of claim 2 wherein the fluoride ion concentration is in the range of from about 0.005 to about 1.0 by weight.
Claim 5
Dependent Claim
23 words
The composition of claim 2 wherein the fluoride ion concentration is in the range of from about 0.02 to about 0.5% by weight.
Claim 6
Dependent Claim
23 words
The composition of claim 2 wherein the zinc ion is present in a concentration of from about 0.02 to about 30.0% by weight.
Claim 7
Dependent Claim
19 words
The composition of claim 5 wherein the zinc ion concentration is from about 0.05 to about 10.0% by weight.
Claim 8
Dependent Claim
19 words
The composition of claim 6 wherein the zinc ion concentration is from about 0.1 to about 5.0% by weight.
Claim 9
Dependent Claim
23 words
The composition of claim 1 wherein the buffering agent is present in a concentration of from about 0.01 to about 10.0% by weight.
Claim 10
Dependent Claim
19 words
The composition of claim 8 wherein the buffering agent concentration is from about 0.05 to about 5.0% by weight.
Claim 11
Dependent Claim
12 words
The composition of claim 1 wherein the buffering agent is sodium gluconate.
Claim 12
Dependent Claim
28 words
The composition of claim 1 wherein the vehicle comprises at least one member selected from the group consisting of glycerol, water, ethanol, polyethylene glycol, propylene glycol and sorbitol.
References Cited (Backward Citations)
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1989-02-03 | 1989-08-05 | 1990-02-04 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1993-02-03 | 1993-08-05 | 1994-02-04 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1997-02-03 | 1997-08-05 | 1998-02-04 | $7700.00 | Window Closed / Lapsed |