US4425325A
Expired / Lapsed
US
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Oral compositions
Assignee: CPPD Inc A CORP OF
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Filing: 1982-02-03
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Granted: 1984-01-10
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Expires: 2002-02-03
Abstract
Abstract The astringency of an oral composition containing biologically active zinc ions may be reduced by the addition of glycine to the composition, and adjustment of the pH to about 4.5 to 9.4. In addition, zinc may be kept in a biologically active solution at this pH by the addition of glycine. The zinc-glycine combination serves as an anticalculus-antiplaque-antimalodor agent in oral compositions.
Inventors
- 👤 Thomas W. Ritchey
- 👤 John M. Weaver
- 👤 Martin Sapone
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 20:08
CPC Classifications
A; A61; A61K; A61K8/00; A61K8/18; A61K8/30; A61K8/40; A61K8/44; A61K8/19; A61K8/27; A61Q; A61Q11/00
Claims Analysis
Total Claims: 15
Claim 1
Independent Claim
88 words
An oral composition having a pH of about 4.5 to about 9.4 comprising a physiologically acceptable zinc compound at a level sufficient to produce about 50 to about 30,000 parts per million of zinc wherein said zinc compounds may have a tendency to produce the organoleptically displeasing effect of astringency and glycine at a level of about 0.01% to about 7% by weight, based on the total weight of the composition as the essential effective agent reducing astringency or said glycine serving to effectively solubilize said zinc compounds.
Claim 2
Dependent Claim
88 words
An oral composition having a pH of about 4.5 to about 9.4 comprising a physiologically acceptable zinc compound at a level sufficient to produce about 50 to about 30,000 parts per million of zinc wherein said zinc compounds may have a tendency to produce the organoleptically displeasing effect of astringency and glycine at a level of about 0.01% to about 7% by weight, based on the total weight of the composition as the essential effective agent reducing astringency or said glycine serving to effectively solubilize said zinc compounds.
Claim 3
Dependent Claim
13 words
The composition according to claim 1 wherein the zinc salt is zinc chloride.
Claim 4
Dependent Claim
13 words
The composition according to claim 1 wherein the zinc compound is zinc glycinate.
Claim 5
Dependent Claim
23 words
The composition according to claim 1 wherein the zinc compound is present at a level sufficient to produce about 6,000 ppm of zinc.
Claim 6
Dependent Claim
22 words
The composition according to claim 1 wherein the glycine is present at a level of about 0.1% to about 3% by weight.
Claim 7
Dependent Claim
24 words
The composition according to claim 1 wherein glycine is present in a ratio of at least about two parts glycine to one part zinc.
Claim 8
Dependent Claim
37 words
The composition according to claim 1 which is in the form of a mouthwash and wherein the zinc compound is present at a level sufficient to produce about 0.04% to about 0.7% by weight of soluble zinc.
Claim 9
Independent Claim
59 words
A method for reducing the astringency of an oral composition containing biologically active zinc in an amount of about 50 to about 30,000 parts per million comprising adding glycine to said composition in an amount of from at least about 0.01% to about 7% by weight and adjusting the pH of said composition to about 4.5 to about 9.4.
Claim 10
Independent Claim
59 words
A method for reducing the astringency of an oral composition containing biologically active zinc in an amount of about 50 to about 30,000 parts per million comprising adding glycine to said composition in an amount of from at least about 0.01% to about 7% by weight and adjusting the pH of said composition to about 4.5 to about 9.4.
Claim 11
Dependent Claim
13 words
The method defined in claim 8 wherein the oral product is a mouthwash.
Claim 12
Dependent Claim
13 words
The method defined in claim 8 wherein the oral product is a toothpaste.
Claim 13
Dependent Claim
14 words
The method defined in claim 8 wherein the zinc is supplied by zinc chloride.
Claim 14
Dependent Claim
14 words
The method defined in claim 8 wherein the pH is adjusted to about 7.
Claim 15
Dependent Claim
24 words
The method of claim 8 wherein the glycine is present in a ratio of at least about 2 parts glycine to 1 part zinc.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1987-01-09 | 1987-07-11 | 1988-01-10 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1991-01-09 | 1991-07-11 | 1992-01-10 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1995-01-09 | 1995-07-11 | 1996-01-10 | $7700.00 | Window Closed / Lapsed |