Patent US4560781A successfully refreshed from Google Patents.
US4560781A
Expired / Lapsed
US
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Glycolic acid platinum complexes
Assignee: Shionogi and Co Ltd
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Filing: 1983-11-17
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Granted: 1985-12-24
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Expires: 2003-11-17
Abstract
Abstract Novel water-soluble glycolic acid platinum complexes which have more potent antitumor activity with lower nephrotoxicity than cisplatin are provided. They can be administered parenterally to mice attacked by malignant tumors. Prepared from dinitrato-platinum complexes of amines on treatment with anion exchange resins and subsequent reaction with glycolic acid.
Inventors
- 👤 Tetsushi Totani
- 👤 Katsutoshi Aono
- 👤 Michihiro Komura
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-28 21:56
CPC Classifications
C; C07; C07F; C07F17/00; C07F17/02; C07F15/00; C07F15/0006; C07F15/0086; C07F15/0093; A; A61; A61P; A61P35/00; C07C; C07C51/00; C07C51/41; C07C51/418; C07C59/00; C07C59/01; C07C59/06
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
30 words
A compound of the general formula: ##STR13## [wherein X and Y each is straight or branched chain alkylamine, or X and Y taken together form ethylenediamine, 1,2-diaminocyclohexane, exo-cis-2,3-diaminobicyclo[2.2.1]heptane, or 1,2-diaminoadamantane].
Claim 2
Dependent Claim
30 words
A compound of the general formula: ##STR13## [wherein X and Y each is straight or branched chain alkylamine, or X and Y taken together form ethylenediamine, 1,2-diaminocyclohexane, exo-cis-2,3-diaminobicyclo[2.2.1]heptane, or 1,2-diaminoadamantane].
Claim 3
Dependent Claim
8 words
The compound claimed in claim 1, namely, glycolato[exo-cis-2,3-diaminobicyclo[2.2.1]heptane]platinum(II).
Claim 4
Dependent Claim
8 words
The compound claimed in claim 1, namely, glycolato(1,2-diaminoadamantane)platinum(II).
Claim 5
Dependent Claim
8 words
The compound claimed in claim 1, namely, glycolato(cis-1,2-diaminocyclohexane)platinum(II).
Claim 6
Dependent Claim
8 words
The compound claimed in claim 1, namely, glycolato(trans-l-1,2-diaminocyclohexane)platinum(II).
Claim 7
Dependent Claim
8 words
The compound claimed in claim 1, namely, glycolato(1,2-diaminoethane)platinum(II).
Claim 8
Dependent Claim
8 words
The compound claimed in claim 1, namely, glycolato[cis-bis(methylamine)]platinum(II).
References Cited (Backward Citations)
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US4230631A
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US4250189A
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US4271085A
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US4359425A
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US4466924A
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1988-12-23 | 1989-06-24 | 1989-12-24 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1992-12-23 | 1993-06-24 | 1993-12-24 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1996-12-23 | 1997-06-24 | 1997-12-24 | $7700.00 | Window Closed / Lapsed |