US4359425A
Expired / Lapsed
US
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Organo-platinum complex
Assignee: Shionogi and Co Ltd
•
Filing: 1981-03-31
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Granted: 1982-11-16
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Expires: 2001-03-31
Abstract
Abstract Organo-platinum complexes of the following formula having excellent antitumor actions: ##STR1## X and Y each or taken together is a mono- or bi-functional ligand selected from the group consisting of halogeno, nitrato, sulfonato, monocarboxylato (mono-functional), sulfato, and dicarboxylato (bi-functional); and each of n and m is an integer of 1 or 2.
Inventors
- 👤 Tetsushi Totani
- 👤 Kenji Yamaguchi
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-29 17:44
CPC Classifications
C; C07; C07C; C07C59/00; C07C59/01; C07C59/06; A; A61; A61P; A61P35/00; C07C53/00; C07C53/15; C07C53/16; C07C55/00; C07C55/02; C07C55/06; C07C55/07; C07C55/08; C07C63/00; C07C63/307; C07F; C07F15/00; C07F15/0006; C07F15/0086; C07F15/0093
Claims Analysis
Total Claims: 20
Claim 1
Independent Claim
49 words
An organo-platinum complex of the formula: ##STR14## wherein X and Y each or taken together is a mono- or bi-functional ligand selected from the group consisting of halogeno, nitrato, sulfonato, monocarboxylato (mono-functional), sulfato, and dicarboxylato (bi-functional); and each of n and m is an integer of 1 or 2.
Claim 2
Dependent Claim
49 words
An organo-platinum complex of the formula: ##STR14## wherein X and Y each or taken together is a mono- or bi-functional ligand selected from the group consisting of halogeno, nitrato, sulfonato, monocarboxylato (mono-functional), sulfato, and dicarboxylato (bi-functional); and each of n and m is an integer of 1 or 2.
Claim 3
Dependent Claim
25 words
An organo-platinum complex claimed in claim 1, wherein either n or m is an integer of 1 and the other is an integer of 2.
Claim 4
Dependent Claim
14 words
An organo-platinum complex claimed in claim 1, wherein X and Y each is halogeno.
Claim 5
Dependent Claim
14 words
An organo-platinum complex claimed in claim 1, wherein X and Y each is nitrato.
Claim 6
Dependent Claim
14 words
An organo-platinum complex claimed in claim 1, wherein X and Y each is chloroacetato.
Claim 7
Dependent Claim
14 words
An organo-platinum complex claimed in claim 1, wherein X and Y each is glycolato.
Claim 8
Dependent Claim
14 words
An organo-platinum complex claimed in claim 1, wherein X and Y each is glucuronato.
Claim 9
Dependent Claim
15 words
An organo-platinum complex claimed in claim 1, wherein X and Y taken together is sulfato.
Claim 10
Dependent Claim
15 words
An organo-platinum complex claimed in claim 1, wherein X and Y taken together is oxalato.
Claim 11
Dependent Claim
15 words
An organo-platinum complex claimed in claim 1, wherein X and Y taken together is malonato.
Claim 12
Dependent Claim
9 words
An organo-platinum complex claimed in claim 1, namely dichloro[exo,cis-2,3-diaminobicyclo(2.2.1)heptane]platinum(II).
Claim 13
Dependent Claim
9 words
An organo-platinum compex claimed in claim 1, namely dinitrato[exo,cis-2,3-diaminobicyclo(2.2.1)heptane]platinum(II).
Claim 14
Dependent Claim
9 words
An organo-platinum complex, claimed in claim 1, namely sulfato[exo,cis-2,3-diaminobicyclo(2.2.1)heptane]platinum(II).
Claim 15
Dependent Claim
9 words
An organo-platinum complex, claimed in claim 1, namely malonato[exo,cis-2,3-diaminobicyclo(2.2.1)heptane]platinum(II).
Claim 16
Dependent Claim
9 words
An organo-platinum complex, claimed in claim 1, namely bis(chloroacetato)[exo,cis-2,3-diaminobicyclo(2.2.1)heptane]platinum(II).
Claim 17
Dependent Claim
9 words
An organo-platinum complex, claimed in claim 1, namely hemimellitato[exo,cis-2,3-diaminobicyclo(2.2.1)heptane]platinum(II).
Claim 18
Dependent Claim
9 words
An organo-platinum complex, claimed in claim 1, namely oxalato[exo,cis-2,3-diaminobicyclo(2.2.1)heptane]platinum(II).
Claim 19
Dependent Claim
9 words
An organo-platinum complex, claimed in claim 1, namely bis(glycolato)[exo,cis-2,3-diaminobicyclo(2.2.1)heptane]platinum(II).
Claim 20
Dependent Claim
9 words
An organo-platinum complex, claimed in claim 1, namely bis(glucuronato)[exo,cis-2,3-diaminobicyclo(2.2.1)heptane]platinum(II).
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1985-11-15 | 1986-05-17 | 1986-11-16 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1989-11-15 | 1990-05-17 | 1990-11-16 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1993-11-15 | 1994-05-17 | 1994-11-16 | $7700.00 | Window Closed / Lapsed |