US4530905A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Crosslinked gelatin foams
Assignee: Dow Chemical Co
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Filing: 1984-10-25
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Granted: 1985-07-23
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Expires: 2004-10-25
Abstract
Abstract Gelatins are crosslinked in a non-anhydrous environment to yield water-swellable, essentially water-insoluble foams. The gelatin is contacted with a polyisocyanate at a pH between about 6 and about 8 and subjected to a high rate of agitation. The process of this invention can be employed to immobilize proteins, enzymes, antibodies, etc.
Inventors
- 👤 Harold H. Freedman
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-02 20:03
CPC Classifications
C; C09; C09H; C09H7/00; C08; C08G; C08G18/00; C08G18/06; C08G18/28; C08G18/40; C08G18/64; C08G18/6415; C08G18/6446; C08G2210/00
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
39 words
A process for providing stable, water-swellable, essentially water-insoluble foam wherein a polyisocyanate is contacted with an aqueous liquid comprising a gelatin which is at a specific pH and which is subjected to a sufficiently high rate of shear agitation.
Claim 2
Dependent Claim
39 words
A process for providing stable, water-swellable, essentially water-insoluble foam wherein a polyisocyanate is contacted with an aqueous liquid comprising a gelatin which is at a specific pH and which is subjected to a sufficiently high rate of shear agitation.
Claim 3
Dependent Claim
12 words
A process of claim 1 wherein said aqueous liquid comprises essentially water.
Claim 4
Dependent Claim
17 words
A process of claim 2 wherein the rate of agitation is in excess of about 3,000 rpm.
Claim 5
Dependent Claim
16 words
A process of claim 1 wherein said specific pH ranges from about 6 to about 8.
Claim 6
Dependent Claim
17 words
A process of claim 1 wherein said aqueous liquid comprises water and a water immiscible organic solvent.
Claim 7
Dependent Claim
11 words
A process of claim 1 wherein said polyisocyanate is a diisocyanate.
Claim 8
Dependent Claim
12 words
A process of claim 1 wherein said aqueous liquid comprises a protein.
Claim 9
Dependent Claim
11 words
A process of claim 7 wherein said protein is an enzyme.
Claim 10
Dependent Claim
46 words
A process for covalently immobilizing a protein wherein said protein is contacted with a gelatin and a polyisocyanate in an aqueous liquid which is at a specific pH and which is subjected to a sufficiently high rate of agitation to yield a water-swellable, essentially water-insoluble foam.
Claim 11
Dependent Claim
46 words
A process for covalently immobilizing a protein wherein said protein is contacted with a gelatin and a polyisocyanate in an aqueous liquid which is at a specific pH and which is subjected to a sufficiently high rate of agitation to yield a water-swellable, essentially water-insoluble foam.
Claim 12
Dependent Claim
11 words
A process of claim 9 wherein said protein is an enzyme.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1988-07-22 | 1989-01-21 | 1989-07-23 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1992-07-22 | 1993-01-21 | 1993-07-23 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1996-07-22 | 1997-01-21 | 1997-07-23 | $7700.00 | Window Closed / Lapsed |