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US4339432A Expired / Lapsed US ⏱️ 0.0 years remaining

Oral mouthwash containing zinc and glycine

Assignee: CPPD Inc A CORP OF
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Filing: 1981-02-17
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Granted: 1982-07-13
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Expires: 2001-02-17
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Abstract

Abstract The astringency of an oral mouthwash composition containing biologically active zinc ions may be reduced by the addition of glycine to the composition, and adjustment of the pH to 4.5 to 8. In addition, zinc ions may be kept in a biologically active solution at this pH by the addition of glycine. The zinc-glycine combination serves as an anticalculus-antiplaque agent in oral compositions.

Inventors

  • 👤 Thomas W. Ritchey
  • 👤 John M. Weaver
  • 👤 Martin Sapone

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-04 10:32
CPC Classifications
A; A61; A61Q; A61Q11/00; A61K; A61K8/00; A61K8/18; A61K8/19; A61K8/27; A61K8/30; A61K8/40; A61K8/44

Claims Analysis

Total Claims: 11
Claim 1
Independent Claim 99 words
An oral mouthwash composition having a pH of about 4.5 to about 8.0 comprising a physiologically acceptable zinc salt or zinc glycinate in an amount sufficient to provide about 0.04% to about 0.7% by weight of the composition of soluble zinc ions wherein said zinc salts may have a tendency to produce the organoleptically displeasing effect of astringency; and glycine at a level of about 0.01% to about 4% by weight of the composition as the essential effective agent reducing astringency or said glycine serving to effectively solubilize said zinc salts at a pH of about 8 or above.
Claim 2
Dependent Claim 99 words
An oral mouthwash composition having a pH of about 4.5 to about 8.0 comprising a physiologically acceptable zinc salt or zinc glycinate in an amount sufficient to provide about 0.04% to about 0.7% by weight of the composition of soluble zinc ions wherein said zinc salts may have a tendency to produce the organoleptically displeasing effect of astringency; and glycine at a level of about 0.01% to about 4% by weight of the composition as the essential effective agent reducing astringency or said glycine serving to effectively solubilize said zinc salts at a pH of about 8 or above.
Claim 3
Dependent Claim 13 words
The composition according to claim 1 wherein the zinc salt is zinc chloride.
Claim 4
Dependent Claim 32 words
The composition according to claim 1 wherein the zinc salt is present in an amount sufficient to provide a level of soluble zinc ions of about 0.1% to about 0.3% by weight.
Claim 5
Dependent Claim 22 words
The composition according to claim 1 wherein the glycine is present at a level of about 0.1% to about 1% by weight.
Claim 6
Dependent Claim 22 words
The composition according to claim 1 wherein the zinc salt is at a level of about 0.04% to about 2.0% by weight.
Claim 7
Independent Claim 63 words
A method for reducing the astringency of an oral mouthwash composition containing biologically active zinc ions in an amount of about 0.04% to about 0.7% by weight of the composition comprising adding glycine to said composition in an amount of from about 0.01% to about 4% by weight and adjusting the pH of said composition to about 4.5 to about 8.0, or above.
Claim 8
Independent Claim 63 words
A method for reducing the astringency of an oral mouthwash composition containing biologically active zinc ions in an amount of about 0.04% to about 0.7% by weight of the composition comprising adding glycine to said composition in an amount of from about 0.01% to about 4% by weight and adjusting the pH of said composition to about 4.5 to about 8.0, or above.
Claim 9
Dependent Claim 15 words
The method defined in claim 6 wherein the zinc ions are supplied by zinc chloride.
Claim 10
Dependent Claim 14 words
The method defined in claim 6 wherein the pH is adjusted to about 7.
Claim 11
Dependent Claim 13 words
The method of claim 6 wherein the pH is adjusted with sodium carbonate.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1985-07-12 1986-01-11 1986-07-13 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1989-07-12 1990-01-11 1990-07-13 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1993-07-12 1994-01-11 1994-07-13 $7700.00 Window Closed / Lapsed

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