Patent US4301028A successfully refreshed from Google Patents.
US4301028A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Control reagent for heparin activity determination
Assignee: Roche Diagnostics GmbH
•
Filing: 1980-01-09
•
Granted: 1981-11-17
•
Expires: 2000-01-09
Abstract
Abstract A control reagent for heparin activity determination comprising 20 to 1500 USP heparin, 2000 to 30000 IU antithrombin III, 0.15 to 1.5 millimoles serum albumin, 0.005 to 0.05 mole ethylenediaminetetraacetic acid sodium salt, 0 to 0.4 mole saccharose, 2000 to 20000 U aprotinin, and buffer substance, pH 6.5 to 7.5, per liter of control reagent solution.
Inventors
- 👤 Knut Bartl
- 👤 Joachim Ziegenhorn
- 👤 Peter Wunderwald
- 👤 Klaus Beaucamp
- 👤 Helmut Lill
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-26 15:02
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/96; G01N2400/00; G01N2400/10; G01N2400/38; G01N2400/40; G01N33/86; Y; Y10; Y10T; Y10T436/00; Y10T436/10; Y10T436/106664
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
57 words
A control reagent for heparin activity determination comprising 20 to 1500 USP heparin, 2000 to 30000 IU antithrombin III, 0.15 to 1.5 to millimoles serum albumin, 0.005 to 0.05 mole ethylenediaminetetraacetic acid sodium salt, 0 to 0.4 mole saccharose, 2000 to 20000 U aprotinin, and buffer substance, pH 6.5 to 7.5, per liter of control reagent solution.
Claim 2
Dependent Claim
57 words
A control reagent for heparin activity determination comprising 20 to 1500 USP heparin, 2000 to 30000 IU antithrombin III, 0.15 to 1.5 to millimoles serum albumin, 0.005 to 0.05 mole ethylenediaminetetraacetic acid sodium salt, 0 to 0.4 mole saccharose, 2000 to 20000 U aprotinin, and buffer substance, pH 6.5 to 7.5, per liter of control reagent solution.
Claim 3
Dependent Claim
10 words
Control reagent as claimed in claim 1 in dissolved form.
Claim 4
Dependent Claim
10 words
Control reagent as claimed in claim 1 in lyophilized form.
Claim 5
Dependent Claim
40 words
Control reagent as claimed in claim 1 comprising 0.8 to 1.0 millimole bovine serum albumin, 0.009 to 0.011 mole ethylenediaminetetraacetic acid sodium salt, 0.03 to 0.05 mole saccharose, 8000 to 12000 U aprotinin, and buffer substance, pH 6.9 to 7.1.
References Cited (Backward Citations)
US3030272A
Cited
US4056484A
Cited
US3985618A
Cited
US4106990A
Cited
US4067777A
Cited
US4090977A
Cited
US4127502A
Cited
DE2812943A1
Cited
US4234682A
Cited
US4216117A
Cited
US4195072A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1984-11-16 | 1985-05-18 | 1985-11-17 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1988-11-16 | 1989-05-18 | 1989-11-17 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1992-11-16 | 1993-05-18 | 1993-11-17 | $7700.00 | Window Closed / Lapsed |