US4301028A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Control reagent for heparin activity determination
Assignee: Roche Diagnostics GmbH
•
Filing: 1980-01-09
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Granted: 1981-11-17
•
Expires: 2000-01-09
Abstract
Abstract A control reagent for heparin activity determination comprising 20 to 1500 USP heparin, 2000 to 30000 IU antithrombin III, 0.15 to 1.5 millimoles serum albumin, 0.005 to 0.05 mole ethylenediaminetetraacetic acid sodium salt, 0 to 0.4 mole saccharose, 2000 to 20000 U aprotinin, and buffer substance, pH 6.5 to 7.5, per liter of control reagent solution.
Inventors
- 👤 Knut Bartl
- 👤 Joachim Ziegenhorn
- 👤 Peter Wunderwald
- 👤 Klaus Beaucamp
- 👤 Helmut Lill
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-26 04:54
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/96; G01N2400/00; G01N2400/10; G01N2400/38; G01N2400/40; G01N33/86; Y; Y10; Y10T; Y10T436/00; Y10T436/10; Y10T436/106664
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
57 words
A control reagent for heparin activity determination comprising 20 to 1500 USP heparin, 2000 to 30000 IU antithrombin III, 0.15 to 1.5 to millimoles serum albumin, 0.005 to 0.05 mole ethylenediaminetetraacetic acid sodium salt, 0 to 0.4 mole saccharose, 2000 to 20000 U aprotinin, and buffer substance, pH 6.5 to 7.5, per liter of control reagent solution.
Claim 2
Dependent Claim
57 words
A control reagent for heparin activity determination comprising 20 to 1500 USP heparin, 2000 to 30000 IU antithrombin III, 0.15 to 1.5 to millimoles serum albumin, 0.005 to 0.05 mole ethylenediaminetetraacetic acid sodium salt, 0 to 0.4 mole saccharose, 2000 to 20000 U aprotinin, and buffer substance, pH 6.5 to 7.5, per liter of control reagent solution.
Claim 3
Dependent Claim
10 words
Control reagent as claimed in claim 1 in dissolved form.
Claim 4
Dependent Claim
10 words
Control reagent as claimed in claim 1 in lyophilized form.
Claim 5
Dependent Claim
40 words
Control reagent as claimed in claim 1 comprising 0.8 to 1.0 millimole bovine serum albumin, 0.009 to 0.011 mole ethylenediaminetetraacetic acid sodium salt, 0.03 to 0.05 mole saccharose, 8000 to 12000 U aprotinin, and buffer substance, pH 6.9 to 7.1.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1984-11-16 | 1985-05-18 | 1985-11-17 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1988-11-16 | 1989-05-18 | 1989-11-17 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1992-11-16 | 1993-05-18 | 1993-11-17 | $7700.00 | Window Closed / Lapsed |