US8034003B2
Active / In Force
US
⏱️ 1.4 years remaining
Tissue extraction and collection device
Assignee: DePuy Spine LLC
•
Filing: 2008-03-27
•
Granted: 2011-10-11
•
Expires: 2028-03-27
Abstract
Abstract Methods and device for extracting and collecting tissue, which can be used for example in tissue engineering and grafting applications, are disclosed. In one embodiment, a device can include an outer tube. A rotatable shaft can be disposed within the outer tube can have a tissue harvesting tip formed on its distal end, the tissue harvesting tip being effective to excise tissue upon rotation thereof. A tissue collection device can be included to receive and collected excised tissue, and the tissue collection device can indicate the amount of tissue collected therein. For example, the tissue collection device can include a straining element which collects excised tissue and an indicator by which to assess the amount of collected tissue. In some embodiments, the tissue collection device can translate to indicate the amount of collected tissue. In many cases, devices disclosed herein can include driving mechanisms that are adapted to drive a tissue harvesting tip such that the tip excises soft tissue, but stops when contacting bone (or soon after contacting bone). In some embodiments, the tissue harvesting tip can be effective to excise viable tissue samples, such that the samples can exhibit desirable proportions of viable cells. Further, in some embodiments, the tissue harvesting tips can excise a tissue sample with tissue particles falling in certain size ranges.
Inventors
- 👤 Robert S. Pesce
- 👤 Shelby Cook
- 👤 Kristian DiMatteo
- 👤 Kevin Ranucci
- 👤 Robert Boock
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 12:05
CPC Classifications
A; A61; A61B; A61B10/00; A61B10/02; A61B10/0233; A61B10/025; A61B17/00; A61B17/16; A61B17/1635; A61B17/32; A61B17/320016; A61B17/32002; A61B10/0096; A61B10/0266; A61B10/0283; A61B2017/320064; A61B90/00; A61B90/08; A61B2090/0807
Claims Analysis
Total Claims: 31
Claim 1
Independent Claim
123 words
A tissue extraction and collection device, comprising: an outer tube; a shaft rotatably disposed within the outer tube and having a tissue harvesting tip disposed at a distal end thereof, the tissue harvesting tip being effective to excise tissue upon rotation thereof; and a tissue collection device coupled to the outer tube for receiving excised tissue and fluid flow therefrom, the tissue collection device being configured to indicate an amount of excised tissue collected therein via one or more indicators included in the tissue collection device, the one or more indicators being effective to indicate displacement of at least a portion of the tissue collection device, the displacement resulting from collection of tissue in the tissue collecting device which overcomes a spring bias.
Claim 2
Dependent Claim
123 words
A tissue extraction and collection device, comprising: an outer tube; a shaft rotatably disposed within the outer tube and having a tissue harvesting tip disposed at a distal end thereof, the tissue harvesting tip being effective to excise tissue upon rotation thereof; and a tissue collection device coupled to the outer tube for receiving excised tissue and fluid flow therefrom, the tissue collection device being configured to indicate an amount of excised tissue collected therein via one or more indicators included in the tissue collection device, the one or more indicators being effective to indicate displacement of at least a portion of the tissue collection device, the displacement resulting from collection of tissue in the tissue collecting device which overcomes a spring bias.
Claim 3
Dependent Claim
76 words
The device of claim 1 , wherein the tissue collection device comprises: a substantially transparent portion and a tissue collection chamber disposed therein so as to be at least partially viewable through the substantially transparent portion; and, one or more visual indicators disposed on any of the substantially transparent portion or the tissue collection chamber to indicate a displacement of the tissue collection chamber which corresponds to the amount of tissue in the tissue collection chamber.
Claim 4
Dependent Claim
29 words
The tissue collection device of claim 2 , wherein the visual indicator is adapted to indicate when about 50-1000 mg of tissue is disposed in the tissue collection chamber.
Claim 5
Dependent Claim
33 words
The device of claim 1 , wherein the tissue collection device comprises a container having an inlet and outlet for receiving fluid flow therethrough and a tissue collection chamber disposed within the container.
Claim 6
Dependent Claim
49 words
The device of claim 4 , wherein the tissue collection chamber is translatable along a longitudinal axis thereof such that fluid flow through the container is effective to translate the tissue collection chamber within the container, the indicator indicating longitudinal displacement of the tissue collection chamber within the container.
Claim 7
Dependent Claim
63 words
The device of claim 5 , further comprising a biasing element biasing the tissue collection chamber along the longitudinal axis thereof, wherein fluid flow through the container is effective to overcome the biasing element to translate the tissue collection chamber within the container such that the displacement of the tissue collection chamber corresponds to an amount of tissue in the tissue collection chamber.
Claim 8
Dependent Claim
21 words
The device of claim 4 , wherein the tissue collection chamber includes a straining element for collecting tissue and passing fluid.
Claim 9
Dependent Claim
23 words
The device of claim 7 , wherein the straining element comprises any of a mesh, a filter, a screen, and a perforated surface.
Claim 10
Dependent Claim
39 words
The device of claim 4 , wherein at least a portion of the tissue collection chamber extends across a lumen formed in the container such that substantially all fluid flow through the container flows through the tissue collection chamber.
Claim 11
Dependent Claim
70 words
The device of claim 1 , wherein the tissue collection device includes a substantially transparent portion and a tissue collection chamber disposed therein so as to be at least partially viewable through the substantially transparent portion, and wherein the indicator comprises one or more visual indicators disposed on any of the substantially transparent portion or the tissue collection chamber to indicate the amount of tissue in the tissue collection device.
Claim 12
Dependent Claim
29 words
The tissue collection device of claim 10 , wherein the visual indicator is adapted to indicate when about 50-1000 mg of tissue is disposed in the tissue collection device.
Claim 13
Dependent Claim
17 words
The device of claim 1 , further comprising a handle housing from which the outer tube extends.
Claim 14
Dependent Claim
21 words
The device of claim 1 , further comprising a driver mechanism coupled to the shaft for rotating the tissue harvesting tip.
Claim 15
Dependent Claim
34 words
The device of claim 1 , further comprising a port for coupling to a vacuum source, the vacuum source being effective to draw tissue through at least a portion of the tissue collection device.
Claim 16
Dependent Claim
125 words
A tissue extraction and collection device, comprising: an outer tube; a shaft rotatably disposed within the outer tube and having a tissue harvesting tip disposed at a distal end thereof, the tissue harvesting tip being effective to excise tissue upon rotation thereof; and a tissue collection device coupled to the outer tube for receiving excised tissue and fluid flow therefrom, the tissue collection device having a container having an inlet and outlet for receiving fluid flow therethrough, a tissue collection chamber movably disposed within the container, wherein the tissue collection chamber moves in response to an amount of tissue collected in the chamber against a bias of a spring, and an indicator effective to indicate longitudinal displacement of the tissue collection chamber within the container.
Claim 17
Dependent Claim
125 words
A tissue extraction and collection device, comprising: an outer tube; a shaft rotatably disposed within the outer tube and having a tissue harvesting tip disposed at a distal end thereof, the tissue harvesting tip being effective to excise tissue upon rotation thereof; and a tissue collection device coupled to the outer tube for receiving excised tissue and fluid flow therefrom, the tissue collection device having a container having an inlet and outlet for receiving fluid flow therethrough, a tissue collection chamber movably disposed within the container, wherein the tissue collection chamber moves in response to an amount of tissue collected in the chamber against a bias of a spring, and an indicator effective to indicate longitudinal displacement of the tissue collection chamber within the container.
Claim 18
Dependent Claim
34 words
The device of claim 15 , wherein the tissue collection device is coupled to the outer tube by a transfer tube extending through a housing coupled to a proximal end of the outer tube.
Claim 19
Dependent Claim
15 words
The device of claim 15 , wherein the container comprises a substantially transparent cylindrical tube.
Claim 20
Dependent Claim
28 words
The device of claim 15 , wherein the tissue collection chamber includes a staining element configured to allow fluid to pass therethrough while preventing passage of excised tissue.
Claim 21
Dependent Claim
30 words
The device of claim 15 , wherein the tissue collection device further includes a biasing element configured to bias the tissue collection chamber along a longitudinal axis of the container.
Claim 22
Dependent Claim
16 words
The device of claim 15 , wherein the indicator comprises a reference line on the container.
Claim 23
Dependent Claim
126 words
A tissue extraction and collection device, comprising: a housing configured to be grasped by a user; an outer shaft extending distally from a distal end of the housing; an inner shaft rotatably disposed within the outer shaft and having a tissue harvesting tip disposed at a distal end thereof, the tissue harvesting tip being effective to excise tissue upon rotation thereof; a container removably coupled to the housing and in fluid communication with the outer shaft; and a tissue collection chamber movably disposed within the container and biased via a spring toward one of a proximal end and a distal end of the container, the tissue collection chamber being configured to receive and retain tissue excised by the inner shaft while allowing fluid to flow therethrough.
Claim 24
Dependent Claim
126 words
A tissue extraction and collection device, comprising: a housing configured to be grasped by a user; an outer shaft extending distally from a distal end of the housing; an inner shaft rotatably disposed within the outer shaft and having a tissue harvesting tip disposed at a distal end thereof, the tissue harvesting tip being effective to excise tissue upon rotation thereof; a container removably coupled to the housing and in fluid communication with the outer shaft; and a tissue collection chamber movably disposed within the container and biased via a spring toward one of a proximal end and a distal end of the container, the tissue collection chamber being configured to receive and retain tissue excised by the inner shaft while allowing fluid to flow therethrough.
Claim 25
Dependent Claim
32 words
The device of claim 21 , further comprising an indicator on one of the container and the tissue collection chamber for indicating an amount of tissue retained within the tissue collection chamber.
Claim 26
Dependent Claim
32 words
The device of claim 21 , further comprising an indicator on one of the container and the tissue collection chamber for indicating longitudinal displacement of the tissue collection chamber within the container.
Claim 27
Dependent Claim
23 words
The device of claim 21 , wherein movement of the tissue collection chamber corresponds to an amount of tissue collected in the chamber.
Claim 28
Dependent Claim
88 words
A tissue extraction and collection device, comprising: an outer tube; a shaft rotatably disposed within the outer tube and having a tissue harvesting tip disposed at a distal end thereof, the tissue harvesting tip being effective to excise tissue upon rotation thereof; and a tissue collection device coupled to the outer tube for receiving excised tissue and fluid flow therefrom, a portion of the tissue collection device being spring biased and configured to translate along a longitudinal axis of the tissue collection device as tissue is collected therein.
Claim 29
Dependent Claim
88 words
A tissue extraction and collection device, comprising: an outer tube; a shaft rotatably disposed within the outer tube and having a tissue harvesting tip disposed at a distal end thereof, the tissue harvesting tip being effective to excise tissue upon rotation thereof; and a tissue collection device coupled to the outer tube for receiving excised tissue and fluid flow therefrom, a portion of the tissue collection device being spring biased and configured to translate along a longitudinal axis of the tissue collection device as tissue is collected therein.
Claim 30
Dependent Claim
23 words
The device of claim 25 , wherein the tissue collection device includes an indicator effective to indicate an amount of tissue collected therein.
Claim 31
Dependent Claim
28 words
The device of claim 25 , wherein translation of the portion of the tissue collection device corresponds to an amount of tissue collected in the tissue collection device.
References Cited (Backward Citations)
US1337998A
Cited
US3604417A
Cited
US3810545A
Cited
US3698561A
Cited
US3814079A
Cited
US3937222A
Cited
US4366822A
Cited
US4469153A
Cited
US4553553A
Cited
US4438769A
Cited
US4690672A
Cited
US4649919A
Cited
US4842578A
Cited
US5041138A
Cited
US4844064A
Cited
US5195956A
Cited
US4960130A
Cited
US5077012A
Cited
US5387236A
Cited
US5252301A
Cited
US5494044A
Cited
JPH03136640A
Cited
US20020091406A1
Cited
US20020099401A1
Cited
US6174313B1
Cited
US5269785A
Cited
US6543455B2
Cited
US20020029055A1
Cited
US20020045903A1
Cited
US20030009237A1
Cited
US20020055755A1
Cited
US5403317A
Cited
US20020091403A1
Cited
US20020082631A1
Cited
US5694951A
Cited
US5370609A
Cited
US5197483A
Cited
US5593423A
Cited
US5108422A
Cited
US5206023A
Cited
US5108381A
Cited
US20040169311A1
Cited
EP0527312B1
Cited
US5186714A
Cited
US5333627A
Cited
US5338294A
Cited
US6135977A
Cited
US5489291A
Cited
US5649547A
Cited
US5526822A
Cited
US5551778A
Cited
US5398690A
Cited
US5527330A
Cited
US5900361A
Cited
US5575293A
Cited
US5804366A
Cited
US6017348A
Cited
US6214369B1
Cited
US6216573B1
Cited
US5944686A
Cited
US5871462A
Cited
US6325806B1
Cited
US6071284A
Cited
US5827305A
Cited
US20020091401A1
Cited
US6218182B1
Cited
US6242247B1
Cited
US5788667A
Cited
US5759190A
Cited
US6120514A
Cited
US6010476A
Cited
WO1998024373A1
Cited
WO1998024372A1
Cited
US5871454A
Cited
US5949044A
Cited
US6846314B2
Cited
US6110176A
Cited
US5913859A
Cited
US6358252B1
Cited
US6537567B1
Cited
US6875442B2
Cited
US6053923A
Cited
US6378527B1
Cited
WO1999058066A1
Cited
US6352555B1
Cited
US6921380B1
Cited
US20030114936A1
Cited
US6022354A
Cited
US6783532B2
Cited
US6066153A
Cited
US6299763B1
Cited
US20020177802A1
Cited
US6375635B1
Cited
US6497707B1
Cited
US6179840B1
Cited
US6436110B2
Cited
US6423073B2
Cited
US6447517B1
Cited
US6402766B2
Cited
US6364884B1
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2014-10-10 | 2015-04-11 | 2015-10-11 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2018-10-10 | 2019-04-11 | 2019-10-11 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2022-10-10 | 2023-04-11 | 2023-10-11 | $7700.00 | Window Closed / Lapsed |