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US6787013B2 Expired / Lapsed US ⏱️ 0.0 years remaining

Biosensor

Assignee: Eumed Biotechnology Co Ltd
•
Filing: 2001-09-10
•
Granted: 2004-09-07
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Expires: 2021-09-10
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Abstract

Abstract A spacer forming method for a biosensor that has a biosensor possessing a capillary sampling channel and electrical connecting tracks for the use of a specific portable meter. A pair of electrodes is printed on an insulating base plate to be the transducer of the electrochemical biosensor by means of the screen-printing technology. The advanced thick-film printing technology is employed to construct the spacer component of the sampling channel that precisely controls the volume of a sample solution. Therefore, the spacer forming method reduces the usage of adhesive that otherwise causes a serious problem during a continuous punching procedure. Furthermore, the embedded switch pad on the biosensor is introduced to be instead of a micro switch in a connector of the portable meter.

Inventors

  • 👤 Ching-Yu Chang
  • 👤 Cherng-Jyh Lee
  • 👤 Tzer-Ming Chen

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-29 02:47
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/53; G01N33/543; G01N33/54366; G01N33/54373; G01N33/5438; A; A61; A61B; A61B5/00; A61B5/145; A61B5/14532; C; C12; C12Q; C12Q1/00; C12Q1/001; A61B2562/00; A61B2562/02; A61B2562/0295; Y; Y10; Y10T; Y10T29/00; Y10T29/49; Y10T29/49002; Y10T29/49105; Y10T29/49117; Y10T29/49124; Y10T29/49126; Y10T29/4913; Y10T29/49155; Y10T29/49156

Claims Analysis

Total Claims: 11
Claim 1
Independent Claim 327 words
A biosensor comprising: a substrate ( 1 ) formed as a base of the biosensor; an anode conducting track ( 2 ) and a cathode conducting track ( 2 ′) mounted on the substrate ( 1 ) to be a working electrode conducting track and a counter electrode conducting track respectively; a pair of electrode tracks ( 4 , 4 ′) disclosed on the corresponding conducting track ( 2 , 2 ′) to provide a suitable surface for electrochemical measurement of the biosensor; a switch comprising a switch pad ( 5 ) and a conducting pad ( 3 ), wherein the switch pad ( 5 ) is constructed on a conducting pad ( 3 ), and the switch controls actuation of the electrical system when the biosensor is inserted in a connector of a meter; an insulating layer ( 6 ) disposed on the electrode tracks ( 4 , 4 ′) and the switch pad ( 5 ), and having an opening defined therein to construct a reaction area ( 7 ) and a connecting area ( 14 ); a spacer layer ( 9 ) disposed on the insulating layer ( 6 ) and having a simple ditch ( 10 ) defined in the spacer layer ( 9 ) to correspond to the reaction area ( 7 ) and construct walls of the reaction area ( 7 ) to guide the sample solution flow; a reagent layer ( 8 ) disposed on the reaction area ( 7 ) and re-dissolved rapidly when the reagent layer ( 8 ) contacts with the sample solution; a protecting layer ( 11 ) having a hydrophilic membrane adhered on one face directed toward to the biosensor and traversely mounted on the sample ditch ( 10 ) of the spacer layer ( 9 ) to form an inlet port ( 15 ) and an outlet port ( 16 ) so that a sampling channel ( 13 ) is constructed inside the biosensor.
Claim 2
Dependent Claim 327 words
A biosensor comprising: a substrate ( 1 ) formed as a base of the biosensor; an anode conducting track ( 2 ) and a cathode conducting track ( 2 ′) mounted on the substrate ( 1 ) to be a working electrode conducting track and a counter electrode conducting track respectively; a pair of electrode tracks ( 4 , 4 ′) disclosed on the corresponding conducting track ( 2 , 2 ′) to provide a suitable surface for electrochemical measurement of the biosensor; a switch comprising a switch pad ( 5 ) and a conducting pad ( 3 ), wherein the switch pad ( 5 ) is constructed on a conducting pad ( 3 ), and the switch controls actuation of the electrical system when the biosensor is inserted in a connector of a meter; an insulating layer ( 6 ) disposed on the electrode tracks ( 4 , 4 ′) and the switch pad ( 5 ), and having an opening defined therein to construct a reaction area ( 7 ) and a connecting area ( 14 ); a spacer layer ( 9 ) disposed on the insulating layer ( 6 ) and having a simple ditch ( 10 ) defined in the spacer layer ( 9 ) to correspond to the reaction area ( 7 ) and construct walls of the reaction area ( 7 ) to guide the sample solution flow; a reagent layer ( 8 ) disposed on the reaction area ( 7 ) and re-dissolved rapidly when the reagent layer ( 8 ) contacts with the sample solution; a protecting layer ( 11 ) having a hydrophilic membrane adhered on one face directed toward to the biosensor and traversely mounted on the sample ditch ( 10 ) of the spacer layer ( 9 ) to form an inlet port ( 15 ) and an outlet port ( 16 ) so that a sampling channel ( 13 ) is constructed inside the biosensor.
Claim 3
Dependent Claim 49 words
The biosensor as claimed in claim 1 , wherein the substrate ( 10 ) is made of polymer materials selected from the following group comprising: polyvinyl chloride (PVC), polyethylene terephthalate (PET), polycarbonate (PC), polypropylene (PP), polyethylene (PE), polybutylene terephthalate (PBT), polystyrene (PVDF), polyamide (PA), bakelite, fiberglass, glass and ceramics.
Claim 4
Dependent Claim 50 words
The biosensor as claimed in claim 1 , wherein the conducting tracks ( 2 , 2 ′) and the conducting pad ( 3 ) are made of conductive materials selected from the following group comprising: carbon paste, silver paste, silver chloride paste, gold paste, palladium paste, gold platinum, and palladium.
Claim 5
Dependent Claim 43 words
The biosensor as claimed in claim 1 , wherein the electrode tracks ( 4 , 4 ′) and the switch pad ( 5 ) are made of materials selected form the following group: carbon paste, gold paste, palladium paste, gold, platinum, and palladium.
Claim 6
Dependent Claim 44 words
The biosensor as claimed in claim 1 , wherein the insulating layer ( 6 ) is made of materials selected from the following group: acrylic resin, epoxy resin, polyurethane resin, silicon resin, phenol resin, alkyd resin, maleic alkyd resin, urea resin and polyester resin.
Claim 7
Dependent Claim 45 words
The biosensor as claimed in claim 1 , wherein the insulating spacer layer ( 9 ) is made of materials selected from the following group: acrylic resin, epoxy resin, polyurethane resin, silicon resin, phenol resin, alkyd resin, maleic alkyd resin, urea resin, and polyester resin.
Claim 8
Dependent Claim 31 words
The biosensor as claimed in claim 1 , wherein the reagent layer ( 8 ) is composed of an enzyme, a buffer solution, a carrier, an electrical media, and a surfactant.
Claim 9
Dependent Claim 29 words
The biosensor as claimed in claim 7 , wherein the reagent ( 8 ) has a preferred composition comprising: Glucose oxidase, PVA, Potassium ferricyanide, Phosphate buffer, and Triton X-100.
Claim 10
Dependent Claim 26 words
The biosensor as claimed in claim 1 , wherein material of the protecting layer is selected from polyvinyl chloride (PVC), polyethylene terephthalate (PET) and polypropylene (PP).
Claim 11
Dependent Claim 39 words
The biosensor as claimed in claim 1 , wherein material of the hydrophilic membrane is selected form at least one of the following group: Triton X-100, polyoxymethylene sorbitan, starch, carboxymethyl cellulose, gelatin, acrylate, polyethylene glycol, polyvinyl alcohol, and polyvinylpyrrolidone.

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