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US6179872B1 Expired / Lapsed US ⏱️ 0.0 years remaining

Biopolymer matt for use in tissue repair and reconstruction

Assignee: Medtronic International Ltd Hong Kong
•
Filing: 1998-03-17
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Granted: 2001-01-30
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Expires: 2018-03-17
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Abstract

Abstract Biopolymer matt, biopolymer matt composites, biopolymer matt compositions, and methods of preparing the matt and composite matts are described. Also described are biocompatible constructs which include extracellular matrix macromolecules and methods of preparing these constructs. The matt, matt compositions and biocompatible constructs of the invention can be used in tissue repair and reconstruction.

Inventors

  • 👤 Eugene Bell
  • 👤 Tracy M. Sioussat
  • 👤 Michael J. Begley

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 14:38
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/50; A61L27/60; A61L27/14; A61L27/22; A61L27/24; A61L27/36; A61L27/38; A61L27/56; Y; Y10; Y10T; Y10T428/00; Y10T428/249921; Y10T428/249953; Y10T442/00; Y10T442/20; Y10T442/2525

Claims Analysis

Total Claims: 14
Claim 1
Independent Claim 14 words
A resorbable nonporous biopolymer matt comprising a densely packed random array of biopolymer fibrils.
Claim 2
Dependent Claim 14 words
A resorbable nonporous biopolymer matt comprising a densely packed random array of biopolymer fibrils.
Claim 3
Dependent Claim 33 words
The biopolymer matt of claim 1 , wherein said biopolymer fibrils are selected from the group consisting of collagen, laminin, elastin, fibronectin, fibrinogen, thrombospondin, gelatin, polysaccharides, poly- 1 -amino acids and combinations thereof.
Claim 4
Dependent Claim 15 words
The biopolymer matt of claim 1 , wherein said biopolymer fibrils are derived from collagen.
Claim 5
Dependent Claim 14 words
The biopolymer matt of claim 3 , wherein said collagen is fetal porcine collagen.
Claim 6
Dependent Claim 26 words
The biopolymer matt of claim 1 , wherein said biopolymer matt further comprises macromolecules necessary for cell growth, morphogenesis, differentiation, or tissue building and combinations thereof.
Claim 7
Dependent Claim 13 words
The biopolymer matt of claim 1 , wherein the biopolymer fibrils are crosslinked.
Claim 8
Dependent Claim 27 words
The biopolymer matt of claim 1 , further including a resorbable polymer selected from the group consisting of fibers, braids, bundles of fibers, fabrics and nonwoven fabrics.
Claim 9
Dependent Claim 13 words
The biopolymer matt of claim 1 , wherein said biopolymer further includes pores.
Claim 10
Dependent Claim 16 words
The biopolymer matt of claim 1 , wherein said matt is in or on a support.
Claim 11
Dependent Claim 12 words
The biopolymer matt of claim 9 , wherein said support is porous.
Claim 12
Dependent Claim 79 words
The biopolymer matt of claim 10 , wherein said biopolymer matt is bound to a single density biopolymer foam comprising a network of communicating microcompartments having biopolymer molecules and/or biopolymer filaments interspersed within the wall of the microcompartments, wherein the microcompartments: have volume dimensions of x, y, and z, wherein x=length, y=width, and z=height, are substantially equal, and range from about 1 μm to about 300 μm; and have an average wall thickness of less than about 10 μm.
Claim 13
Dependent Claim 17 words
The biopolymer matt of claim 11 , wherein said biopolymer foam is derived from fetal porcine collagen.
Claim 14
Dependent Claim 14 words
The biopolymer matt of claim 1 , wherein said biopolymer matt further comprises cells.

References Cited (Backward Citations)

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USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 2004-01-30 2004-07-31 2005-01-30 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2008-01-30 2008-07-31 2009-01-30 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2012-01-30 2012-07-31 2013-01-30 $7700.00 Window Closed / Lapsed

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