US5263983A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Medical material and prosthetic skin in which cells can invade
Assignee: OSferionBiomaterials Corp
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Filing: 1989-03-09
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Granted: 1993-11-23
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Expires: 2009-03-09
Abstract
Abstract PCT No. PCT/JP89/00257 Sec. 371 Date Sep. 7, 1990 Sec. 102(e) Date Sep. 7, 1990 PCT Filed Mar. 9, 1989 PCT Pub. No. WO89/08465 PCT Pub. Date Sep. 21, 1989.Disclosed is a cell-penetrable medical material in which cells can invade, comprising denatured collagen with helix content of 0 to 80%, and carrier substance having higher resistance to enzyme decomposition than the denatured collagen. An artificial skin in which this medical material is used as the wound contact layer, and its preferred manufacturing methods are also disclosed.
Inventors
- 👤 Katsutoshi Yoshizato
- 👤 Jun Konishi
- 👤 Mikio Koide
- 👤 Kaori Oyamada
- 👤 Ken-ichi Ohsaki
- 👤 Takeo Katakura
- 👤 Yuichi Mori
- 👤 Ken Tatebe
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 18:07
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/36; A61L27/3683; A61L27/3695; A61L27/14; A61L27/22; A61L27/24; A61L27/50; A61L27/56; A61L27/60; C; C12; C12N; C12N5/00; C12N5/0062; C12N5/0068; A61F; A61F2310/00; A61F2310/00005; A61F2310/00365; Y; Y10; Y10S; Y10S128/00; Y10S128/08
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
30 words
A cell-penetrable medical material, comprising denatured collagen having a triple chain helix content of 0 to 80%, and a carrier possessing higher resistance to enzymatic decomposition than the denatured collagen.
Claim 2
Dependent Claim
30 words
A cell-penetrable medical material, comprising denatured collagen having a triple chain helix content of 0 to 80%, and a carrier possessing higher resistance to enzymatic decomposition than the denatured collagen.
Claim 3
Dependent Claim
18 words
The medical material of claim 1, wherein the denatured collagen lacks an antigenic portion at a molecular terminus.
Claim 4
Dependent Claim
24 words
The medical material of claim 1, wherein the carrier is selected from a group consisting of collagen, fibroin, polyactic acid, mucopolysaccharide, and arginic acid.
Claim 5
Dependent Claim
12 words
The medical material of claim 3, wherein the carrier is undenatured collagen.
Claim 6
Dependent Claim
19 words
The medical material of claim 3, wherein the carrier is collagen lacking an antigenic portion at a molecular terminus.
Claim 7
Dependent Claim
15 words
The medical material of claim 3, wherein the carrier is collagen with a crosslinked structure.
Claim 8
Dependent Claim
12 words
The medical material of claim 3, wherein the carrier is fibrous collagen.
Claim 9
Dependent Claim
14 words
The medical material of claim 7, wherein the fibrous collagen has a crosslinked structure.
Claim 10
Dependent Claim
12 words
The medical material of claim 1, wherein the material is a film.
Claim 11
Dependent Claim
15 words
The medical material of claim 1, wherein the carrier is dispersed in the denatured collagen.
Claim 12
Dependent Claim
12 words
The medical material of claim 1, wherein the material is a sponge.
Claim 13
Dependent Claim
23 words
The medical material of claim 11, wherein the carrier forms a spongy matrix, and the denatured collagen is contained in the spongy matrix.
Claim 14
Dependent Claim
23 words
The medical material of claim 1, wherein the ratio of denatured collagen to carrier is in the range of 5 to 80% w/v.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1996-11-22 | 1997-05-24 | 1997-11-23 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2000-11-22 | 2001-05-24 | 2001-11-23 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2004-11-22 | 2005-05-24 | 2005-11-23 | $7700.00 | Window Closed / Lapsed |