US6013099A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Medical device for delivering a water-insoluble therapeutic salt or substance
Assignee: Medtronic Inc
•
Filing: 1998-04-29
•
Granted: 2000-01-11
•
Expires: 2018-04-29
Abstract
Abstract A device useful for localized delivery of a therapeutic material is provided. The device includes a structure including a porous material; and a water-insoluble salt of a therapeutic material dispersed in the porous material. The water-insoluble salt is formed by contacting an aqueous solution of a therapeutic salt with a heavy metal water-soluble salt dispersed throughout a substantial portion of the porous material. The porous material can be made of a polymer other than fibrin with fibrin incorporated into the pores, which can be the only layer of polymeric material on the medical device (e.g., stent). A new method for preparing a porous polymer material on a medical device.
Inventors
- 👤 Thomas Q. Dinh
- 👤 Rodney G. Wolff
- 👤 Eric P. Berg
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-26 07:55
CPC Classifications
A; A61; A61F; A61F2/00; A61F2/82; A61F2/86; A61F2/88; A61F2250/00; A61F2250/0058; A61F2250/0067; A61N; A61N5/00; A61N5/10; A61N5/1001; A61N5/1002
Claims Analysis
Total Claims: 15
Claim 1
Independent Claim
33 words
A medical device having at least one blood-contacting surface comprising: a non-fibrin porous material having fibrin incorporated therein; and a water-insoluble therapeutic salt dispersed in at least a portion of the porous material.
Claim 2
Dependent Claim
33 words
A medical device having at least one blood-contacting surface comprising: a non-fibrin porous material having fibrin incorporated therein; and a water-insoluble therapeutic salt dispersed in at least a portion of the porous material.
Claim 3
Dependent Claim
14 words
The medical device of claim 1 wherein the non-fibrin porous material comprises a film.
Claim 4
Dependent Claim
37 words
The medical device of claim 2 wherein the non-fibrin porous material is selected from the group consisting of silicone, polyurethane, polysulfone, cellulose, polyethylene, polypropylene, polyamide, polyester, polytetrafluoroethylene, and a combination of two or more of these materials.
Claim 5
Dependent Claim
17 words
The medical device of claim 2 wherein the water-insoluble salt comprises a salt of an antithrombotic material.
Claim 6
Dependent Claim
12 words
The medical device of claim 4 wherein the antithrombotic material is heparin.
Claim 7
Dependent Claim
26 words
The medical device of claim 5 wherein the water-insoluble salt is selected from the group consisting of barium, calcium and silver salts of the antithrombotic material.
Claim 8
Dependent Claim
41 words
An intravascular stent comprising: a generally cylindrical stent body; a single layer of a polymeric film comprising a non-fibrin porous polymer with fibrin incorporated therein; and a water-insoluble therapeutic salt dispersed in at least a portion of the porous polymeric film.
Claim 9
Dependent Claim
41 words
An intravascular stent comprising: a generally cylindrical stent body; a single layer of a polymeric film comprising a non-fibrin porous polymer with fibrin incorporated therein; and a water-insoluble therapeutic salt dispersed in at least a portion of the porous polymeric film.
Claim 10
Dependent Claim
38 words
The stent of claim 7 wherein the non-fibrin porous polymer film comprises a material selected from the group of silicone, polyurethane, polysulfone, cellulose, polyethylene, polypropylene, polyamide, polyester, polytetrafluoroethylene, and a combination of two or more of these materials.
Claim 11
Dependent Claim
14 words
The stent of claim 8 wherein the non-fibrin porous polymer film comprises a polyurethane.
Claim 12
Dependent Claim
14 words
The stent of claim 7 wherein the water-insoluble therapeutic salt is an antithrombotic salt.
Claim 13
Dependent Claim
14 words
The stent of claim 10 wherein the antithrombotic salt is a salt of heparin.
Claim 14
Dependent Claim
22 words
The stent of claim 11 wherein the water-insoluble heparin salt is selected from the group consisting of silver, barium and calcium salts.
Claim 15
Dependent Claim
16 words
The medical device of claim 1 which is in the form of a generally cylindrical stent.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2003-01-10 | 2003-07-12 | 2004-01-11 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2007-01-10 | 2007-07-12 | 2008-01-11 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2011-01-10 | 2011-07-12 | 2012-01-11 | $7700.00 | Window Closed / Lapsed |