US5641502A
Expired / Lapsed
US
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Biodegradable moldable surgical material
Assignee: United States Surgical Corp
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Filing: 1995-06-07
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Granted: 1997-06-24
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Expires: 2015-06-07
Abstract
Abstract A moldable biodegradable surgical material is made of a bioabsorbable polymer derived from hydroxyacids, tactones, carbonates, etheresters, anhydrides, orthoesters and copolymers, terpolymers and/or blends thereof, the polymer blended with at least one surface active agent selected from the group consisting of fatty acid ester and poly(oxypropylene)/poly(oxyethylene) block copolymer. In one embodiment, a leaching agent is blended with the above-mentioned surgical material. Methods of making moldable biodegradable surgical material are provided. The surgical material may be used as a moldable bone wax in connection with repair of wounds and is an adaptable aid for any appropriate surgical use, e.g., hemostat, anchor, patch etc.
Inventors
- 👤 Walter Skalla
- 👤 Steven L. Bennett
- 👤 Ying Jiang
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 13:05
CPC Classifications
A; A61; A61L; A61L31/00; A61L31/04; A61L31/041; A61L24/00; A61L24/001; A61L24/0036; A61L24/04; A61L24/043; A61L24/046; A61L27/00; A61L27/14; A61L27/18; A61L27/26; A61L27/50; A61L27/56; A61L31/06
Claims Analysis
Total Claims: 19
Claim 1
Independent Claim
73 words
A hand moldable biodegradable surgical material comprising a blend of a bioabsorbable polymer and a surface active agent selected from the group consisting of sorbitan fatty acid ester and poly(oxypropylene)/poly(oxyethylene) block copolymer and a leaching agent selected from the group consisting of calcium carbonate, calcium chloride, tricalcium phosphate and hydroxyapatite wherein the leaching agent is present in an amount ranging from about 1 percent to about 70 percent by weight of the material.
Claim 2
Dependent Claim
73 words
A hand moldable biodegradable surgical material comprising a blend of a bioabsorbable polymer and a surface active agent selected from the group consisting of sorbitan fatty acid ester and poly(oxypropylene)/poly(oxyethylene) block copolymer and a leaching agent selected from the group consisting of calcium carbonate, calcium chloride, tricalcium phosphate and hydroxyapatite wherein the leaching agent is present in an amount ranging from about 1 percent to about 70 percent by weight of the material.
Claim 3
Dependent Claim
38 words
A hand moldable biodegradable surgical material according to claim 1 wherein the bioabsorbable polymer is derived from a member selected from the group consisting of hydroxyacids, lactones, carbonates, etheresters, anhydrides, esteramides, orthoesters, and copolymers, terpolymers and blends thereof.
Claim 4
Dependent Claim
33 words
A hand moldable biodegradable surgical material according to claim 2 wherein the bioabsorbable polymer is selected from the group consisting of polylactide, polyglycolide, polydioxanone, polycaprolactone, polytrimethylene carbonate and copolymers, terpolymers and blends thereof.
Claim 5
Dependent Claim
22 words
A hand moldable biodegradable surgical material according to claim 3 wherein the bioabsorbable polymer is a star polymer of glycolide and caprolactone.
Claim 6
Dependent Claim
34 words
A hand moldable biodegradable surgical material according to claim 4 wherein glycolide is present in an amount of about 9.8 weight percent and caprolactone is present in an amount of about 90.2 weight percent.
Claim 7
Dependent Claim
32 words
A hand moldable biodegradable surgical material according to claim 1 wherein the sorbitan fatty acid ester is present in an amount ranging from about 10 weight percent to about 90 weight percent.
Claim 8
Dependent Claim
22 words
A hand moldable biodegradable surgical material according to claim 1 wherein the sorbitan fatty acid ester is polyoxyethylene sorbitan fatty acid ester.
Claim 9
Dependent Claim
21 words
A hand moldable biodegradable surgical material according to claim 7 wherein the polyoxyethylene sorbitan fatty acid ester is polyoxyethylene sorbitan monopalmitate.
Claim 10
Dependent Claim
32 words
A hand moldable biodegradable surgical material according to claim 1 wherein the bioabsorbable polymer is a star polymer of glycolide and caprolactone and the sorbitan fatty acid ester is polyoxyethylene sorbitan monopalmitate.
Claim 11
Dependent Claim
31 words
A hand moldable biodegradable surgical material according to claim 1 wherein the poly(oxypropylene)poly(oxyethylene) block copolymer is present in an amount ranging from about 2 weight percent to about 55 weight percent.
Claim 12
Dependent Claim
34 words
A hand moldable biodegradable surgical material according to claim 1 wherein the bioabsorbable material is a star polymer of glycolide and caprolactone and the poly(oxypropylene)poly(oxyethylene) block copolymer has a molecular weight of about 7500.
Claim 13
Dependent Claim
24 words
A method of effecting hemostasis comprising providing a moldable biodegradable surgical material according to claim 1 and applying the material to a suitable locus.
Claim 14
Independent Claim
80 words
A method of producing a hand moldable biodegradable surgical material comprising providing a bioabsorbable polymer and blending the bioabsorbable polymer with a surface active agent selected from the group consisting of sorbitan fatty acid ester and poly(oxypropylene)/poly(oxyethylene) block copolymer, and a leaching agent selected from the group consisting of calcium carbonate, calcium chloride, tricalcium phosphate and hydroxyapatite wherein the leaching agent is present in an amount ranging from about 1 percent to about 70 percent by weight of the material.
Claim 15
Independent Claim
80 words
A method of producing a hand moldable biodegradable surgical material comprising providing a bioabsorbable polymer and blending the bioabsorbable polymer with a surface active agent selected from the group consisting of sorbitan fatty acid ester and poly(oxypropylene)/poly(oxyethylene) block copolymer, and a leaching agent selected from the group consisting of calcium carbonate, calcium chloride, tricalcium phosphate and hydroxyapatite wherein the leaching agent is present in an amount ranging from about 1 percent to about 70 percent by weight of the material.
Claim 16
Dependent Claim
53 words
A hand moldable biodegradable surgical material comprising a blend of bioabsorbable polymer and a leaching agent selected from the group Consisting of calcium carbonate, calcium chloride, tricalcium phosphate and hydroxyapatite wherein the leaching agent is present in an amount ranging from about 1 percent to about 70 percent by weight of the material.
Claim 17
Dependent Claim
53 words
A hand moldable biodegradable surgical material comprising a blend of bioabsorbable polymer and a leaching agent selected from the group Consisting of calcium carbonate, calcium chloride, tricalcium phosphate and hydroxyapatite wherein the leaching agent is present in an amount ranging from about 1 percent to about 70 percent by weight of the material.
Claim 18
Dependent Claim
38 words
A hand moldable biodegradable surgical material according to claim 1 wherein the bioabsorbable polymer is derived from a member selected from the group consisting of hydroxyacids, lactones, carbonates, estheresters, anhydrides, esteramides, orthoesters, and copolymers, terpolymers and blends thereof.
Claim 19
Dependent Claim
29 words
A hand moldable biodegradable surgical material according to claim 14, wherein the bioabsorbable polymer is a star polymer of glycolide and caprolactone and the leaching agent is tricalcium phosphate.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2000-06-23 | 2000-12-23 | 2001-06-24 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2004-06-23 | 2004-12-23 | 2005-06-24 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2008-06-23 | 2008-12-23 | 2009-06-24 | $7700.00 | Window Closed / Lapsed |