Patent US5740067A successfully refreshed from Google Patents.
US5622686A
Expired / Lapsed
US
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Diagnosis and treatment of viral effects using magnetic metal transferrin particles
Assignee: Individual
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Filing: 1995-06-07
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Granted: 1997-04-22
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Expires: 2015-06-07
Abstract
Abstract This invention provides methods of treatment and/or diagnosis and/or siting of viruses including the AIDS virus and others as well as the cells which they infect. The method comprises introducing near, into or onto the virus or the cell which the virus infects, or both, minute particles. These particles possess ferromagnetic, paramagnetic or diamagnetic properties. After being localized near, in or on the virus or the viral-infected cell, the particles are inductively heated by application of an alternating electromagnetic field. The inductive heating is continued for a period of time sufficient to bring about a temperature rise to a minimum necessary to kill the virus or cell or to desirably alter the behavior of the virus or infected cell. Prior to, during or after treatment, these particles can be used diagnostically to locate and/or map the virus in the living tissue.
Inventors
- 👤 David Gordon, deceased
- 👤 legal representative by Eunice Gordon
- 👤 Robert T. Gordon
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 21:28
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/48; A61K9/50; A61K9/5094; A61K31/00; A61K31/28; A61K31/295; A61K33/00; A61K33/24; A61K33/243; A61K33/244; A61K33/26; A61K41/00; A61K41/0052; A61K49/00; A61K49/06; A61K49/18; A61K49/1818; A61K49/1821; A61K49/1824; A61K49/1827; A61K49/183; G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/53; G01N33/569; G01N33/56983; G01N33/56988; Y; Y10; Y10T; Y10T436/00; Y10T436/24
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
96 words
An in vitro method of diagnosing HIV viral disease or an HIV viral infection in a cell of or from a living host comprising: introducing in vitro into a locus of said virus or cells, particles localizable near, in or on the virus or viral-infected cells, such particles being capable of responding to a magnetic field and being of a size less than 1 micron, whereby the particles are selectively located near, into or on the virus and/or viral-infected cells, wherein said particles are magnetic metal transferrin particles, and measuring a magnetic property of the particles.
Claim 2
Dependent Claim
96 words
An in vitro method of diagnosing HIV viral disease or an HIV viral infection in a cell of or from a living host comprising: introducing in vitro into a locus of said virus or cells, particles localizable near, in or on the virus or viral-infected cells, such particles being capable of responding to a magnetic field and being of a size less than 1 micron, whereby the particles are selectively located near, into or on the virus and/or viral-infected cells, wherein said particles are magnetic metal transferrin particles, and measuring a magnetic property of the particles.
Claim 3
Dependent Claim
21 words
A method of claim 1 wherein said measuring provides a map which identifies the location and/or the concentration of the particles.
Claim 4
Dependent Claim
16 words
A method according to claim 2 wherein a SQUID magnetometer is used for the magnetic mapping.
Claim 5
Dependent Claim
16 words
A method according to claim 2 wherein nuclear magnetic resonance is used to map the particles.
Claim 6
Dependent Claim
16 words
A method according to claim 2 wherein EPR or ESR is used to map the particles.
Claim 7
Dependent Claim
13 words
A method according to claim 1 wherein said virus is an AIDS-causing virus.
Claim 8
Dependent Claim
35 words
A method according to claim 1 wherein said particles comprise a metal which is cobalt, zinc, chromium, nickel, platinum, manganese, a rare earth metal, dysprosium, erbium, gallium, holmium, samarium, terbium, thulium, ytterbium, yttrium or iron.
Claim 9
Dependent Claim
14 words
A method of claim 1 wherein said magnetic particle is ferromagnetic, paramagnetic or diamagnetic.
Claim 10
Dependent Claim
14 words
A method of claim 1 wherein the magnetic particle transferrin is bound to dextran.
Claim 11
Dependent Claim
14 words
A method of claim 1 wherein the particle is Fe 3 O 4 -dextran-transferrin.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2000-04-21 | 2000-10-21 | 2001-04-22 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2004-04-21 | 2004-10-21 | 2005-04-22 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2008-04-21 | 2008-10-21 | 2009-04-22 | $7700.00 | Window Closed / Lapsed |