US5384109A
Expired / Lapsed
US
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Diagnostic magnetometry using superparamagnetic particles
Assignee: GE Healthcare AS
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Filing: 1991-03-30
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Granted: 1995-01-24
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Expires: 2011-03-30
Abstract
Abstract PCT No. PCT/EP91/00619 Sec. 371 Date Nov. 6, 1992 Sec. 102(e) Date Nov. 6, 1992 PCT Filed Mar. 30, 1991 PCT Pub. No. WO91/15243 PCT Pub. Date Oct. 17, 1991.The use of superparamagnetic particles and of paramagnetic materials (such as lanthanide chelates) as contrast agents in magnetometric analysis, especially imaging, and in particular structural and functional, diagnosis or imaging is described.
Inventors
- 👤 Jo Klaveness
- 👤 Thorfinn Ege
- 👤 Scott M. Rocklage
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 21:35
CPC Classifications
A; A61; A61K; A61K49/00; A61K49/06; A61K49/08; A61K49/10; A61K49/12; A61K49/126; A61K49/085; A61K49/101; A61K49/103; A61K49/106; A61K49/14; A61K49/16; A61K49/18; A61K49/1806; A61K49/1812; A61K49/1818; A61K49/1821; A61K49/1824; A61K49/1827; A61K49/1851; A61K49/1854; A61K49/1863; A61K49/1875; A61K49/20; Y; Y10; Y10S; Y10S436/00; Y10S436/806; Y10T; Y10T436/00; Y10T436/24
Claims Analysis
Total Claims: 13
Claim 1
Independent Claim
41 words
A method of generating a magnetometric image of the human or non-human animal body comprising administering to said body a physiologically tolerable superparamagnetic material and generating a magnetometric signal of at least part of said body into which said material distributes.
Claim 2
Independent Claim
41 words
A method of generating a magnetometric image of the human or non-human animal body comprising administering to said body a physiologically tolerable superparamagnetic material and generating a magnetometric signal of at least part of said body into which said material distributes.
Claim 3
Dependent Claim
26 words
A method as claimed in claim 1, wherein said signal is a magnetometric image of at least part of said body into which said material distributes.
Claim 4
Dependent Claim
19 words
A method as claimed in claim 2, wherein said image generated is a two or three dimensional structural image.
Claim 5
Dependent Claim
20 words
A method as claimed in claim 1, wherein said signal is generated using a superconducting quantum interference device (SQUID) magnetometer.
Claim 6
Dependent Claim
17 words
A method as claimed in claim 4, wherein said signal is generated using a multichannel SQUID system.
Claim 7
Dependent Claim
38 words
The method as claimed in claim 1, wherein a superparamagnetic material is used as a magnetometric diagnostic (MD) agent with no pre-magnetization thereof and no magnetic field or with a static magnetic field being imposed during signal generation.
Claim 8
Dependent Claim
49 words
A process for detecting variations in magnetic susceptibility within a human or non-human animal body, comprising administering to said body a physiologically tolerable superparamagnetic material, and with a magnetometer continuously or repeatedly monitoring the magnetic susceptibility of at least a part of said body into which said material distributes.
Claim 9
Dependent Claim
49 words
A process for detecting variations in magnetic susceptibility within a human or non-human animal body, comprising administering to said body a physiologically tolerable superparamagnetic material, and with a magnetometer continuously or repeatedly monitoring the magnetic susceptibility of at least a part of said body into which said material distributes.
Claim 10
Dependent Claim
12 words
A process as claimed in claim 7 comprising generating a magnetometric image.
Claim 11
Dependent Claim
18 words
A process as claimed in claim 7, wherein said magnetometer is a superconducting quantum interference device (SQUID) magnetometer.
Claim 12
Dependent Claim
15 words
A process as claimed in claim 9, wherein said magnetometer is a multichannel SQUID system.
Claim 13
Dependent Claim
38 words
The process as claimed in claim 7, wherein a superparamagnetic material is used as a magnetometric diagnostic (MD) agent with no pre-magnetization thereof and no magnetic field or with a static magnetic field being imposed during signal generation.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1998-01-23 | 1998-07-25 | 1999-01-24 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2002-01-23 | 2002-07-25 | 2003-01-24 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2006-01-23 | 2006-07-25 | 2007-01-24 | $7700.00 | Window Closed / Lapsed |