US5571568A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Multilayered bioelectronic sensors
Assignee: Biocircuits Corp
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Filing: 1995-06-07
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Granted: 1996-11-05
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Expires: 2015-06-07
Abstract
Abstract Bioelectronic sensors are provided employing a thin surfactant polymeric electrically conducting layer to which may be bound members of specific binding pairs. Binding of an analyte or a reagent to the specific binding pair member layer may change the electrical, optical, or structural properties of the layer for measurement of analyte. The change in the polymeric layer provides for a sensitive measurement.
Inventors
- 👤 Hans O. Ribi
- 👤 Todd Guion
- 👤 Paul T. Shafer
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 15:48
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/53; G01N33/536; G01N33/542; G01N33/543; G01N33/54366; G01N33/54373; G01N33/5438; B; B01; B01J; B01J2219/00; B01J2219/00274; B01J2219/00718; B01J2219/0072; B01J2219/00734; Y; Y10; Y10S; Y10S436/00; Y10S436/806
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
97 words
A method of forming a crystalline electrically conducting surfactant layer comprising: spreading over an aqueous subphase on a solid substrate a solution of surfactant comprising polymerizable surfactants capable of forming an electrically conducting surfactant polymer, wherein said aqueous subphase comprises at least one water miscible organic compound; evaporating the solvent of said surfactant solution to produce films; heating said substrate at a temperature and for a time sufficient to cause surfactant melting; cooling said melted dry patches to a temperature of less than about 10° C.; and polymerizing said polymerizable surfactants to said electrically conducting surfactant polymer.
Claim 2
Independent Claim
97 words
A method of forming a crystalline electrically conducting surfactant layer comprising: spreading over an aqueous subphase on a solid substrate a solution of surfactant comprising polymerizable surfactants capable of forming an electrically conducting surfactant polymer, wherein said aqueous subphase comprises at least one water miscible organic compound; evaporating the solvent of said surfactant solution to produce films; heating said substrate at a temperature and for a time sufficient to cause surfactant melting; cooling said melted dry patches to a temperature of less than about 10° C.; and polymerizing said polymerizable surfactants to said electrically conducting surfactant polymer.
Claim 3
Dependent Claim
18 words
A method according to claim 1, wherein said subphase comprises at least one of dimethyl sulfoxide and glycerol.
Claim 4
Dependent Claim
20 words
A method according to claim 2, wherein said subphase comprises from about 1 to 5 volume % of dimethyl sulfoxide.
Claim 5
Dependent Claim
24 words
A method according to claim 2, wherein said heating is to at least about 100° C. and below the boiling point of said subphase.
Claim 6
Dependent Claim
12 words
A method according to claim 1, wherein said polymerization is with radiation.
Claim 7
Dependent Claim
19 words
A method according to claim 1, wherein said polymerizable surfactant is an alkadiyne of at least 6 carbon atoms.
Claim 8
Dependent Claim
26 words
A method according to claim 1, wherein said melting is at at least about 120° C. and said cooling occurs in less than about one minute.
Claim 9
Dependent Claim
16 words
A method according to claim 1, wherein said surfactant layer comprises non-polymerizable non-volatile hydrocarbons or surfactants.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1999-11-05 | 2000-05-06 | 2000-11-05 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2003-11-05 | 2004-05-06 | 2004-11-05 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2007-11-05 | 2008-05-06 | 2008-11-05 | $7700.00 | Window Closed / Lapsed |