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US5482851A Expired / Lapsed US ⏱️ 0.0 years remaining

Nucleic acid encoding TGF-β and its uses

Assignee: Genentech Inc
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Filing: 1993-11-05
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Granted: 1996-01-09
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Expires: 2013-11-05
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Abstract

Abstract Nucleic acid encoding TGF-β has been isolated and cloned into vectors which are replicated in bacteria and expressed in eukaryotic cells. TGFβ is recovered from transformed cultures for use in known therapeutic modalities. Nucleic acid encoding TFG-β is useful in diagnosis and identification of TGF-β clones.

Inventors

  • 👤 Rik M. A. Derynck
  • 👤 David V. Goeddel

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-07 13:05
CPC Classifications
C; C07; C07K; C07K14/00; C07K14/435; C07K14/475; C07K14/495

Claims Analysis

Total Claims: 4
Claim 1
Independent Claim 10 words
A composition comprising human TGF-β and Chinese hamster ovary cells.
Claim 2
Dependent Claim 10 words
A composition comprising human TGF-β and Chinese hamster ovary cells.
Claim 3
Dependent Claim 23 words
A disulfide linked heterodimer of TGFB in which one TGF-β chain is a TGF-β1 chain and the other chain is a TGF-β3 chain.
Claim 4
Dependent Claim 23 words
A disulfide linked heterodimer of TGFB in which one TGF-β chain is a TGF-β1 chain and the other chain is a TGF-β3 chain.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1999-01-08 1999-07-10 2000-01-09 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2003-01-08 2003-07-10 2004-01-09 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2007-01-08 2007-07-10 2008-01-09 $7700.00 Window Closed / Lapsed

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