Patent US5443734A successfully refreshed from Google Patents.
US5443734A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Programmable solid phase extraction and elution device
Assignee: Applied Separations Inc
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Filing: 1993-08-03
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Granted: 1995-08-22
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Expires: 2013-08-03
Abstract
Abstract An automated, integrated system for programmably selectively extracting and purifying one or more particular solutes from a contaminated solution, said purified solutes then being recovered as a concentrated solution suitable for analysis.
Inventors
- 👤 Martin J. Fetner
- 👤 Elwood F. Seasholtz
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 04:13
CPC Classifications
G; G01; G01N; G01N1/00; G01N1/28; G01N1/40; G01N1/405; B; B01; B01D; B01D15/00; B01D15/08; G01N1/02; G01N1/10; G01N1/18; G01N30/00
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
226 words
A method for extracting one or more particular solutes from a sample solution, said method comprising the steps of: a. placing an amount of said sample solution into a non-contaminating receptacle, said receptacle being operatively connected to means adapted to meter predetermined amounts of said solution therefrom; b. programmably introducing at least one metered amount of said sample solution into a selected one or more of a plurality of cartridge receiver tubes, each of said selected receiver tubes containing an amount of the same or a different solid phase extractant or sorbent through which said solution will pass, said sorbent being selected to remove substantially all of one of said particular solutes from said sample solution; c. programmably introducing into said selected receiver tubes a predetermined amount of one or more solvents to pass through said sorbent, said solvents being adapted to selectively dissolve and remove substantially all of any residual sample solution and residual contaminants remaining on or absorbed by said sorbent while permitting substantially all of said particular solute to remain; d. programmably introducing into said selected receiver tubes one or more predetermined amounts of at least one solvent to pass through said sorbent and selectively form a contamination-free solution with a selected one of said particular solutes resident therein; and e. removing said contamination-free solution from said selected receiver tubes for further use.
Claim 2
Independent Claim
226 words
A method for extracting one or more particular solutes from a sample solution, said method comprising the steps of: a. placing an amount of said sample solution into a non-contaminating receptacle, said receptacle being operatively connected to means adapted to meter predetermined amounts of said solution therefrom; b. programmably introducing at least one metered amount of said sample solution into a selected one or more of a plurality of cartridge receiver tubes, each of said selected receiver tubes containing an amount of the same or a different solid phase extractant or sorbent through which said solution will pass, said sorbent being selected to remove substantially all of one of said particular solutes from said sample solution; c. programmably introducing into said selected receiver tubes a predetermined amount of one or more solvents to pass through said sorbent, said solvents being adapted to selectively dissolve and remove substantially all of any residual sample solution and residual contaminants remaining on or absorbed by said sorbent while permitting substantially all of said particular solute to remain; d. programmably introducing into said selected receiver tubes one or more predetermined amounts of at least one solvent to pass through said sorbent and selectively form a contamination-free solution with a selected one of said particular solutes resident therein; and e. removing said contamination-free solution from said selected receiver tubes for further use.
Claim 3
Dependent Claim
22 words
The method of claim 1 wherein the sequential order and amounts of said metered solutions are controlled by a programmable control means.
Claim 4
Dependent Claim
36 words
The method of claim 1 wherein the steps of sequentially introducing selected solutions is controlled by a programmable selection means and the quantitative transfer of said solutions is performed by programmable pump means and valve means.
Claim 5
Dependent Claim
39 words
The method of claim 1 further comprising the step of introducing into said receiver tubes and passing through said sorbent an amount of one or more conditioning solutions before the introduction of the sample solution into the receiver tubes.
Claim 6
Dependent Claim
68 words
The method of claim 1 further comprising the step of flushing the fluid connection between a plurality of inlet ports of a first multi-port valve means and individual stop valves connected to each of the plurality of outlet ports of a second multi-port valve means which connect the sample receptacle and selected solution receptacles to the plurality of cartridge receiver tubes to remove any contaminants from solution residues.
Claim 7
Dependent Claim
68 words
The method of claim 1 further comprising the step of drying the fluid connection between a plurality of inlet ports of a first multi-port valve means and individual stop valves connected to each of the plurality of outlet ports of a second multi-port valve means which connect the sample receptacle and selected solution receptacles to the plurality of cartridge receiver tubes to remove any contaminants from solution residues.
Claim 8
Independent Claim
192 words
A method for extracting one or more particular solutes from a sample solution, said method comprising the steps of: a. placing an amount of said sample solution into at least a selected one of a plurality of cartridge receiver tubes, each of said receiver tubes containing an amount of the same or a different solid phase extractant or sorbent through which said solution will pass, said sorbent being selected to remove substantially all of one of said particular solutes from said sample solution; b. programmably introducing into said selected receiver tubes a predetermined amount of one or more solvents to pass through said sorbent, said solvents being adapted to selectively dissolve and remove substantially all of any residual solution and residual contaminants remaining on or absorbed by said sorbent while permitting substantially all of said particular solute to remain; c. programmably introducing into said selected receiver tubes one or more predetermined amounts of at least one solvent to pass through said sorbent and selectively form a contamination-free solution with a selected one of said particular solute resident therein; and d. removing said contamination-free solution from said selected receiver tubes for further use.
Claim 9
Independent Claim
192 words
A method for extracting one or more particular solutes from a sample solution, said method comprising the steps of: a. placing an amount of said sample solution into at least a selected one of a plurality of cartridge receiver tubes, each of said receiver tubes containing an amount of the same or a different solid phase extractant or sorbent through which said solution will pass, said sorbent being selected to remove substantially all of one of said particular solutes from said sample solution; b. programmably introducing into said selected receiver tubes a predetermined amount of one or more solvents to pass through said sorbent, said solvents being adapted to selectively dissolve and remove substantially all of any residual solution and residual contaminants remaining on or absorbed by said sorbent while permitting substantially all of said particular solute to remain; c. programmably introducing into said selected receiver tubes one or more predetermined amounts of at least one solvent to pass through said sorbent and selectively form a contamination-free solution with a selected one of said particular solute resident therein; and d. removing said contamination-free solution from said selected receiver tubes for further use.
Claim 10
Dependent Claim
22 words
The method of claim 7 wherein the sequential order and amounts of said metered solutions are controlled by a programmable control means.
Claim 11
Dependent Claim
36 words
The method of claim 7 wherein the steps of sequentially introducing selected solutions is controlled by a programmable selection means and the quantitative transfer of said solutions is performed by programmable pump means and valve means.
Claim 12
Dependent Claim
39 words
The method of claim 7 further comprising the step of introducing into said receiver tubes and passing through said sorbent an amount of one or more conditioning solutions before the introduction of the sample solution into the receiver tubes.
Claim 13
Dependent Claim
68 words
The method of claim 7 further comprising the step of flushing the fluid connection between a plurality of inlet ports of a first multi-port valve means and individual stop valves connected to each of the plurality of outlet ports of a second multi-port valve means which connect the sample receptacle and selected solution receptacles to the plurality of cartridge receiver tubes to remove any contaminants from solution residues.
Claim 14
Dependent Claim
68 words
The method of claim 7 further comprising the step of drying the fluid connection between a plurality of inlet ports of a first multi-port valve means and individual stop valves connected to each of the plurality of outlet ports of a second multi-port valve means which connect the sample receptacle and selected solution receptacles to the plurality of cartridge receiver tubes to remove any contaminants from solution residues.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1998-08-21 | 1999-02-20 | 1999-08-22 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2002-08-21 | 2003-02-20 | 2003-08-22 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2006-08-21 | 2007-02-20 | 2007-08-22 | $7700.00 | Window Closed / Lapsed |