Patent US5362420A successfully refreshed from Google Patents.
US5362420A
Expired / Lapsed
US
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Low impedance pressure sensitive adhesive composition and biomedical electrodes using same
Assignee: 3M Co
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Filing: 1993-12-21
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Granted: 1994-11-08
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Expires: 2013-12-21
Abstract
Abstract The present invention discloses a low impedance, water-absorbing, ionically-conductive, hydrophilic pressure sensitive adhesive composition comprising an ionically-conductive, hydrophilic, pressure sensitive adhesive hydrogel and crosslinked poly(N-vinyl lactam) in an amount sufficient to retain low electrical impedance and maintain hydrogel adhesion and cohesion during use of the composition in the presence of water and other moisture tending to plasticize the hydrogel. Crosslinked homopolymers and copolymers of poly(N-vinyl pyrrolidone) having Swelling Capacity of at least 15 milliliters of water per gram of poly(N-vinyl pyrrolidone) are preferred. Adhesion values upon removal from mammalian skin after about four hours of adhesion are not greater than initial adhesion removal values, demonstrating ease of removal of electrodes of the present invention from skin.
Inventors
- 👤 Steven K. Itoh
- 👤 Timothy M. Dietz
- 👤 Rosa Uy
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 23:49
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0014; A61B; A61B5/00; A61B5/24; A61B5/25; A61B5/251; A61B5/257; A61B5/259; A61K47/00; A61K47/30; A61K47/32; A61N; A61N1/00; A61N1/02; A61N1/04; A61N1/0404; A61N1/0408; A61N1/0456; A61N1/0472; A61N1/0492; A61N1/0496; C; C08; C08F; C08F271/00; C08F271/02; C09; C09J; C09J139/00; C09J139/04; C09J139/06; A61N1/0428; A61N1/046; C08L; C08L2666/00; C08L2666/02; C08L33/00; C08L33/02; C09J2301/00; C09J2301/30; C09J2301/302; Y; Y10; Y10S; Y10S526/00; Y10S526/931
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
175 words
A low impedance, water-absorbing, ionically-conductive, hydrophilic pressure sensitive adhesive composition, consisting essentially of: an ionically-conductive, hydrophilic pressure sensitive adhesive hydrogel comprising a polymer, humectant, and water, and radiation crosslinked poly(N-vinyl lactam) homopolymer dispersed as swellable solids in the hydrogel and present in an amount from about 0.5 to about 3.0 weight percent of the composition to retain low electrical impedance and maintain hydrogel adhesion and cohesion during use of the composition in the presence of mammalian body fluids tending to plasticize said hydrogel; wherein said hydrogel polymer is selected from the group consisting of (a) (1) partially neutralized acrylic acid homopolymers, (2) partially neutralized acrylic acid copolymers, (3) copolymers of N-vinyl lactam and a multi-ethylenically unsaturated compound, (4) copolymers of N-vinyl lactam and a carboxylic acid, and (5) an interpenetrating polymer network of hydrophilic crosslinked polymer from a water soluble monomer and a hydrophilic polymer which is not crosslinked; and wherein said radiation crosslinked poly(N-vinyl lactam) homopolymer swellable solids are crosslinked by ionizing radiation prior to dispersion in the hydrogel in a solid state form.
Claim 2
Dependent Claim
175 words
A low impedance, water-absorbing, ionically-conductive, hydrophilic pressure sensitive adhesive composition, consisting essentially of: an ionically-conductive, hydrophilic pressure sensitive adhesive hydrogel comprising a polymer, humectant, and water, and radiation crosslinked poly(N-vinyl lactam) homopolymer dispersed as swellable solids in the hydrogel and present in an amount from about 0.5 to about 3.0 weight percent of the composition to retain low electrical impedance and maintain hydrogel adhesion and cohesion during use of the composition in the presence of mammalian body fluids tending to plasticize said hydrogel; wherein said hydrogel polymer is selected from the group consisting of (a) (1) partially neutralized acrylic acid homopolymers, (2) partially neutralized acrylic acid copolymers, (3) copolymers of N-vinyl lactam and a multi-ethylenically unsaturated compound, (4) copolymers of N-vinyl lactam and a carboxylic acid, and (5) an interpenetrating polymer network of hydrophilic crosslinked polymer from a water soluble monomer and a hydrophilic polymer which is not crosslinked; and wherein said radiation crosslinked poly(N-vinyl lactam) homopolymer swellable solids are crosslinked by ionizing radiation prior to dispersion in the hydrogel in a solid state form.
Claim 3
Dependent Claim
41 words
The composition according to claim 1, wherein said radiation crosslinked poly(N-vinyl lactam) homopolymer swellable solids are particles of radiation crosslinked poly(N-vinyl-2-pyrrolidone) homopolymer having a Swelling Capacity of at least 15 milliliters of water per gram of radiation crosslinked poly (N-vinyl-2-pyrrolidone) homopolymer.
Claim 4
Dependent Claim
33 words
The composition according to claim 2, wherein said radiation crosslinked poly(N-vinyl-2-pyrrolidone) homopolymer swellable solids have a Swelling Capacity of at least 30 milliliters of water per gram of said radiation crosslinked poly(N-vinyl-2-pyrrolidone) homopolymer.
Claim 5
Dependent Claim
30 words
The composition according to claim 1, wherein said radiation crosslinked poly(N-vinyl lactam) homopolymer swellable solids are particles of radiation crosslinked poly(N-vinyl-2-pyrrolidone) homopolymer having a Fikentscher K-value of at least K-15.
Claim 6
Dependent Claim
28 words
The composition according to claim 1, wherein said radiation crosslinked poly(N-vinyl lactam) homopolymer swellable solids comprise from about 1 to about 2 percent by weight of the composition.
Claim 7
Dependent Claim
16 words
The composition according to claim 1, further comprising an iontophoretically active pharmaceutical dispersed in the composition.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1997-11-07 | 1998-05-09 | 1998-11-08 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2001-11-07 | 2002-05-09 | 2002-11-08 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2005-11-07 | 2006-05-09 | 2006-11-08 | $7700.00 | Window Closed / Lapsed |