US5334375A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Antibacterial antiplaque oral composition
Assignee: Colgate Palmolive Co
•
Filing: 1992-07-16
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Granted: 1994-08-02
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Expires: 2012-07-16
Abstract
Abstract An oral composition containing a substantially water insoluble noncationic antibacterial antiplaque agent such as triclosan and a synthetic cross-linked polymer such as cross-linked poly (methylvinyl ether/maleic acid or anhydride) as antibacterial-enhancing agent to enhance delivery of said antibacterial agent to, and the retention thereof on, oral surfaces, and a method of promoting oral hygiene therewith.
Inventors
- 👤 Nuran Nabi
- 👤 Michael Prencipe
- 👤 Abdul Gaffar
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-26 05:13
CPC Classifications
A; A61; A61K; A61K8/00; A61K8/18; A61K8/19; A61K8/24; A61K8/02; A61K8/0216; A61K8/30; A61K8/33; A61K8/34; A61K8/347; A61K8/40; A61K8/42; A61K8/72; A61K8/81; A61K8/8164; A61K8/817; A61K8/8182; A61P; A61P1/00; A61P1/02; A61P31/00; A61P31/04; A61P43/00; A61Q; A61Q11/00
Claims Analysis
Total Claims: 34
Claim 1
Independent Claim
120 words
An oral composition comprising in an orally acceptable vehicle an effective antiplaque amount of a substantially water insoluble noncationic antibacterial agent and an antibacterial-enhancing agent in an amount effective to enhance delivery of said antibacterial agent to, and the retention thereof on, oral surfaces, said antibacterial-enhancing agent comprising a synthetic cross-linked polymer having in a 1 wt.% aqueous solution an elastic or storage modulus G' and a viscous or loss modulus G' substantially independent of frequency in an applied frequency range of 0.1 to 100 radiants/sec., a G' minimum value of 5,000 dynes/sq. cm which varies less than 1 order of magnitude of its original value, and a ratio of G'/G' ranging from more than 0.05 to less than 1.
Claim 2
Dependent Claim
120 words
An oral composition comprising in an orally acceptable vehicle an effective antiplaque amount of a substantially water insoluble noncationic antibacterial agent and an antibacterial-enhancing agent in an amount effective to enhance delivery of said antibacterial agent to, and the retention thereof on, oral surfaces, said antibacterial-enhancing agent comprising a synthetic cross-linked polymer having in a 1 wt.% aqueous solution an elastic or storage modulus G' and a viscous or loss modulus G' substantially independent of frequency in an applied frequency range of 0.1 to 100 radiants/sec., a G' minimum value of 5,000 dynes/sq. cm which varies less than 1 order of magnitude of its original value, and a ratio of G'/G' ranging from more than 0.05 to less than 1.
Claim 3
Dependent Claim
19 words
A composition according to claim 1 wherein said polymer has a molecular weight of about 1,000 to about 5,000,000.
Claim 4
Dependent Claim
26 words
A composition according to claim 2 wherein said polymer contains a plurality of carboxylic, phosphonic, phosphinic or sulfonic acid or acid salt groups or mixtures thereof.
Claim 5
Dependent Claim
36 words
A composition according to claim 3 wherein said polymer is made with a cross-linking agent containing at least two ethylenically unsaturated groups or at least two groups reactive with pendent reactive groups along the polymer chain.
Claim 6
Dependent Claim
22 words
A composition according to claim 4 wherein said polymer comprises a co-polymer of maleic acid or anhydride with another ethylenically unsaturated monomer.
Claim 7
Dependent Claim
14 words
A composition according to claim 5 wherein said other monomer comprises methyl vinyl ether.
Claim 8
Dependent Claim
20 words
A composition according to claim 6 wherein said copolymer is made with 1,7-octadiene, 1,9-decadiene, or polyethylene glycol as cross-linking agent.
Claim 9
Dependent Claim
36 words
A composition according to any of claims 1 to 7 wherein said antibacterial agent comprises a halogenated diphenyl ether, a halogenated salicylanilide, a benzoic ester, a halogenated carbanilide or a phenolic compound or any mixture thereof.
Claim 10
Dependent Claim
19 words
A composition according to any of claims 1 to 7 wherein said antibacterial agent comprises a halogenated diphenyl ether.
Claim 11
Dependent Claim
16 words
A composition according to claim 8 containing about 0.01 to about 5% of said antibacterial agent.
Claim 12
Dependent Claim
15 words
A composition according to claim 10 wherein said antibacterial agent comprises a halogenated diphenyl ether.
Claim 13
Dependent Claim
13 words
A composition according to claim 11 wherein said halogenated diphenyl ether comprises triclosan.
Claim 14
Dependent Claim
30 words
A composition according to any of claims 1 to 7 further containing an effective anticalculus amount of material comprising at least one linear molecularly dehydrated polyphosphate salt as anticalculus agent.
Claim 15
Dependent Claim
18 words
A composition according to claim 13 wherein said material comprises tetrasodium pyrophosphate, tetrapotassium pyrophosphate or a mixture thereof.
Claim 16
Dependent Claim
18 words
A composition according to claim 12 wherein said material comprises tetrasodium pyrophosphate, tetrapotassium pyrophosphate or a mixture thereof.
Claim 17
Dependent Claim
32 words
A composition according to anyone of claims 1 to 7 further containing an amount of a fluoride ion source sufficient to supply about 25 ppm to about 5,000 ppm of fluoride ions.
Claim 18
Dependent Claim
28 words
A composition according to claim 12 further containing an amount of a fluoride ion source sufficient to supply about 25 ppm to about 5,000 ppm of fluoride ions.
Claim 19
Dependent Claim
28 words
A composition according to claim 15 further containing an amount of a fluoride ion source sufficient to supply about 25 ppm to about 5,000 ppm of fluoride ions.
Claim 20
Dependent Claim
24 words
A composition according to anyone of claims 1 to 7 containing an amount of said cross-linked polymer effective to render the composition linearly viscoelastic.
Claim 21
Dependent Claim
20 words
A composition according to claim 12 containing an amount of said cross-linked polymer effective to render the composition linearly viscoelastic.
Claim 22
Dependent Claim
20 words
A composition according to claim 15 containing an amount of said cross-linked polymer effective to render the composition linearly viscoelastic.
Claim 23
Dependent Claim
20 words
A composition according to claim 18 containing an amount of said cross-linked polymer effective to render the composition linearly viscoelastic.
Claim 24
Dependent Claim
30 words
A composition according to any one of claims 1 to 7 in the form of a dentifrice containing a dentally acceptable polishing agent and a vehicle comprising water and humectant.
Claim 25
Dependent Claim
25 words
A composition according to claim 12 in the form of a dentifrice containing a dentally acceptable polishing agent and a vehicle comprising water and humectant.
Claim 26
Dependent Claim
25 words
A composition according to claim 15 in the form of a dentifrice containing a dentally acceptable polishing agent and a vehicle comprising water and humectant.
Claim 27
Dependent Claim
25 words
A composition according to claim 18 in the form of a dentifrice containing a dentally acceptable polishing agent and a vehicle comprising water and humectant.
Claim 28
Dependent Claim
25 words
A composition according to claim 22 in the form of a dentifrice containing a dentally acceptable polishing agent and a vehicle comprising water and humectant.
Claim 29
Independent Claim
27 words
A method of promoting oral hygiene comprising applying to dental surface an effective amount of a composition as defined in any one of claims 1 to 7.
Claim 30
Dependent Claim
22 words
A method of promoting oral hygiene comprising applying to dental surface an effective amount of a composition as defined in claim 12.
Claim 31
Dependent Claim
22 words
A method of promoting oral hygiene comprising applying to dental surface an effective amount of a composition as defined in claim 15.
Claim 32
Dependent Claim
22 words
A method of promoting oral hygiene comprising applying to dental surface an effective amount of a composition as defined in claim 18.
Claim 33
Dependent Claim
22 words
A method of promoting oral hygiene comprising applying to dental surface an effective amount of a composition as defined in claim 22.
Claim 34
Dependent Claim
22 words
A method or promoting oral hygiene comprising applying to dental surface an effective amount of a composition as defined in claim 27.
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