US5032385A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Oral hygiene composition
Assignee: Beecham Group PLC
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Filing: 1986-10-21
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Granted: 1991-07-16
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Expires: 2006-10-21
Abstract
Abstract An oral hygiene composition contains (a) from 0.01 to 2% by weight of Triclosan, (b) from 2 to 10% by weight of polyethylene glycol of molecular weight from 200 to 1000, and (c) 0.1 to 2% by weight of oil-based flavor material. The polyethylene glycol helps to maintain an effective level of orally available Triclosan.
Inventors
- 👤 John V. Reed
- 👤 Carol A. Jeffryes
- 👤 Peter J. Edwards
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-26 07:07
CPC Classifications
A; A61; A61K; A61K8/00; A61K8/18; A61K8/30; A61K8/33; A61K8/39; A61K8/34; A61K8/347; A61Q; A61Q11/00
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
134 words
An oral hygiene composition comprising (a) from 0.01 to 2% by weight of a composition of an antimicrobial compound of formula (I) as the active therapeutic agent ##STR2## in which R 1 is oxygen; each of R 2 and R 6 is a substituent selected from the group consisting of hydrogen, hydroxyl, alkyl and halogen, and each of R 2 , to R 6 , is a substituent selected from the group consisting of hydrogen, hydroxyl, alkyl and halogen; (b) an amount of one or more polyethylene glycols of molecular weight from 200 to 1000 sufficient to increase the oral availability of the antimicrobial compound, said amount being from 2% to 10% by weight of the composition; and (c) from 0.1% to 2% of oil-based flavour material, in combination with an orally acceptable excipient.
Claim 2
Dependent Claim
134 words
An oral hygiene composition comprising (a) from 0.01 to 2% by weight of a composition of an antimicrobial compound of formula (I) as the active therapeutic agent ##STR2## in which R 1 is oxygen; each of R 2 and R 6 is a substituent selected from the group consisting of hydrogen, hydroxyl, alkyl and halogen, and each of R 2 , to R 6 , is a substituent selected from the group consisting of hydrogen, hydroxyl, alkyl and halogen; (b) an amount of one or more polyethylene glycols of molecular weight from 200 to 1000 sufficient to increase the oral availability of the antimicrobial compound, said amount being from 2% to 10% by weight of the composition; and (c) from 0.1% to 2% of oil-based flavour material, in combination with an orally acceptable excipient.
Claim 3
Dependent Claim
17 words
A composition according to claim 1, which contains from 4 to 8% by weight of polyethylene glycol.
Claim 4
Dependent Claim
21 words
A composition according to claim 1 in which the polyethylene glycol has a molecular weight range of from 200 to 600.
Claim 5
Dependent Claim
37 words
A composition according to claim 1, in which the compound of formula (I) is selected from the group consisting of 2, 4, -dichloro-2' -hydroxydiphenyl ether 4, 4' dichloro-2' -hydroxydiphenyl ether and 2, 4, 4' tribromo-2' -hydroxydiphenyl ether.
Claim 6
Dependent Claim
16 words
A composition according to claims 1, which includes from 0.05 to 5% by weight of detergent.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1994-07-15 | 1995-01-14 | 1995-07-16 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1998-07-15 | 1999-01-14 | 1999-07-16 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2002-07-15 | 2003-01-14 | 2003-07-16 | $7700.00 | Window Closed / Lapsed |