US4980153A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Antiplaque oral hygiene composition
Assignee: Beecham Group PLC
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Filing: 1989-03-15
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Granted: 1990-12-25
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Expires: 2009-03-15
Abstract
Abstract An oral hygiene composition in the form of a dentifrice or a mouthwash, comprising: (a) from 0.01 to 2% by weight of the composition of an antibacterial compound of formula (I): ##STR1## in which R 1 is oxygen, sulphur or an alkylene group of from 1 to 6 carbon atoms, each of R 2 to R 6 and R 2 ' to R 6 ' is hydrogen, hydroxyl or halogen; (b) from 0 to 90% by weight of a dentally acceptable abrasive, (c) from 0.1% to 15% by weight of a dialkali or tetra-alkali metal pyrophosphate salt or a mixture thereof and (d) water.
Inventors
- 👤 Robert J. Jackson
- 👤 Nicholas A. Berrill
- 👤 Shawn V. Robbins
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-26 06:30
CPC Classifications
A; A61; A61K; A61K8/00; A61K8/18; A61K8/30; A61K8/33; A61K8/34; A61K8/347; A61K8/19; A61K8/24; A61Q; A61Q11/00
Claims Analysis
Total Claims: 13
Claim 1
Independent Claim
103 words
An oral hygiene composition in the form of dentifrice or mouthwash comprising; (a) 0.01 to 2% by weight of the composition of an antibacterial compound of formula (I): ##STR3## in which R 1 is oxygen, sulphur or an alkylene group of from one to six carbon atoms, and each of R 2 to R 6 and R 2 ' to R 6 ' is hydrogen, hydroxyl or halogen; (b) from 0 to 90% by weight of a dentally acceptable abrasive; (c) from 0.1 to 15% by weight of a dialkali or a tetra-alkali metal pyrophosphate salt, or a mixture thereof, and (d) water.
Claim 2
Dependent Claim
103 words
An oral hygiene composition in the form of dentifrice or mouthwash comprising; (a) 0.01 to 2% by weight of the composition of an antibacterial compound of formula (I): ##STR3## in which R 1 is oxygen, sulphur or an alkylene group of from one to six carbon atoms, and each of R 2 to R 6 and R 2 ' to R 6 ' is hydrogen, hydroxyl or halogen; (b) from 0 to 90% by weight of a dentally acceptable abrasive; (c) from 0.1 to 15% by weight of a dialkali or a tetra-alkali metal pyrophosphate salt, or a mixture thereof, and (d) water.
Claim 3
Dependent Claim
18 words
A composition according to claim 1 wherein the weight range of component (a) is from 0.01 to 1.0%.
Claim 4
Dependent Claim
18 words
A composition according to claim 2 wherein the weight range of component (a) is from 0.05 to 0.5%.
Claim 5
Dependent Claim
18 words
A composition according to claim 1 wherein the weight range of component (b) is from 20 to 75%.
Claim 6
Dependent Claim
18 words
A composition according to claim 1 wherein the weight range of component (c) is from 2 to 10%.
Claim 7
Dependent Claim
19 words
A composition according to claim 1 in which water is present in an amount of from 2 to 95%.
Claim 8
Dependent Claim
31 words
A composition according to claim 1 in which the compound of formula (I) is selected from the group consisting of: 5,5'-dichloro-2,2'-dihydroxydiphenyl methane (Dichlorophene); 2,2'-dihydroxy-3,5,6,3',5',6'-hexachloro-diphenylmethane (Hexachlorophene); 3,3'-dibromo-5,5'-dichloro-2,2'-dihydroxydiphenylmethane (Bromochlorophene); and 2,4,4'-trichloro-2'-hydroxydiphenyl ether (Triclosan).
Claim 9
Dependent Claim
16 words
A composition according to claim 7 in which the compound of formula (I) is 2,4,4'-trichloro-2'-hydroxydiphenyl ether.
Claim 10
Dependent Claim
12 words
A composition according to claim 1 further comprising a water-soluble fluoride-providing compound.
Claim 11
Dependent Claim
27 words
A method of reducing or preventing dental plaque in humans which method comprises contacting the tooth surface thereof with an oral hygiene composition according to claim 1.
Claim 12
Dependent Claim
27 words
A method of reducing or preventing dental plaque in animals, which method comprises contacting the tooth surface thereof with an oral hygiene composition according to claim 1.
Claim 13
Dependent Claim
41 words
A composition according to claim 1 in the form of a dentifrice in which an abrasive is present, wherein the abrasive is selected from the group consisting of calcium carbonate, dicalcium phosphate, calcium pyrophosphate, alumina, silica and synthetic plastics resin particles.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1993-12-24 | 1994-06-25 | 1994-12-25 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1997-12-24 | 1998-06-25 | 1998-12-25 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2001-12-24 | 2002-06-25 | 2002-12-25 | $7700.00 | Window Closed / Lapsed |