Patent US5296500A successfully refreshed from Google Patents.
US5296500A
Expired / Lapsed
US
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Use of N-acetyl-cysteine and derivatives for regulating skin wrinkles and/or skin atrophy
Assignee: TEXTILE RESEARCH INSTITUTE Inc
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Filing: 1993-07-30
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Granted: 1994-03-22
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Expires: 2013-07-30
Abstract
Abstract The present invention relates to a method for regulating wrinkles and/or atrophy in mammalian skin comprising treating the skin with a safe and effective amount of N-acetyl-L-cysteine and/or a derivative thereof.
Inventors
- 👤 Greg G. Hillebrand
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 13:08
CPC Classifications
A; A61; A61Q; A61Q19/00; A61K; A61K8/00; A61K8/18; A61K8/30; A61K8/40; A61K8/44; A61K8/447; A61Q19/08; A61Q17/00; A61Q17/04
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
46 words
A method for regulating wrinkles or atrophy in mammalian skin comprising treating skin in need of such regulation with a safe and effective amount of a composition comprising: a) a safe and effective amount of N-acetyl-L-cysteine or a pharmaceutically-acceptable salt thereof, and b) a pharmaceutically-acceptable carrier.
Claim 2
Independent Claim
46 words
A method for regulating wrinkles or atrophy in mammalian skin comprising treating skin in need of such regulation with a safe and effective amount of a composition comprising: a) a safe and effective amount of N-acetyl-L-cysteine or a pharmaceutically-acceptable salt thereof, and b) a pharmaceutically-acceptable carrier.
Claim 3
Dependent Claim
18 words
The method of claim 1 wherein the composition comprises from about 0.01% to about 50% of the compound.
Claim 4
Dependent Claim
18 words
The method of claim 1 wherein the composition comprises from about 0.1% to about 20% of the compound.
Claim 5
Dependent Claim
13 words
The method of claim 2 wherein the pharmaceutically-acceptable carrier is a topical carrier.
Claim 6
Dependent Claim
16 words
The method of claim 4 wherein the treatment of the skin with the composition is chronic.
Claim 7
Dependent Claim
39 words
The method of claim 5 wherein the treatment of the skin with the composition is for a period of at least about six months comprising application of the composition from about once per week to about two times daily.
Claim 8
Independent Claim
23 words
The method of any of claims 4 and 5 wherein the composition additionally comprises a safe and effective amount of a zinc salt.
Claim 9
Independent Claim
34 words
The method of any of claims 4 and 5 wherein the composition additionally comprises a zinc salt selected from the group consisting of zinc oxide, zinc stearate, zinc sulfate, zinc chloride and zinc acetate.
Claim 10
Independent Claim
23 words
The method of any of claims 4 and 5 wherein the composition additionally comprises a safe and effective amount of a sunscreening agent.
Claim 11
Independent Claim
43 words
The method of any one of claims 4 and 5 wherein the composition additionally comprises another active agent selected from the group consisting of a safe and effective amount of an anti-inflammatory agent, an anti-oxidant, a chelator, a retinoid, and a benzofuran derivative.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1997-03-21 | 1997-09-20 | 1998-03-22 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2001-03-21 | 2001-09-20 | 2002-03-22 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2005-03-21 | 2005-09-20 | 2006-03-22 | $7700.00 | Window Closed / Lapsed |