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US4724239A
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Method of treating chemical ulcers with N,N'-diacetylcystine, N-acetyl homocysteine and N-acetyl cysteine
Assignee: Individual
•
Filing: 1985-09-16
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Granted: 1988-02-09
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Expires: 2005-09-16
Abstract
Abstract A method of treating chemical ulcers caused by leukotriene production, the method comprising the step of applying to the ulcer a compound that interferes with leukotriene production, the compound being selected from the group consisting of N,N'-diacetylcystine, N-acetylhomocysteine and N-acetylcysteine.
Inventors
- 👤 Lee R. Morgan
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 14:06
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/185; A61K31/19; A61K31/195
Claims Analysis
Total Claims: 18
Claim 1
Independent Claim
56 words
A method of treating chemical ulcers in warm-blooded animals caused by leukotriene production, the method comprising the step of: topically applying to the ulcer an amount of a compound sufficient to interfere with leukotriene production and promote healing of the ulcer, the compound being selected from the group consisting of N,N'-diacetylcystine, N-acetyl homocysteine and N-acetyl cysteine.
Claim 2
Independent Claim
56 words
A method of treating chemical ulcers in warm-blooded animals caused by leukotriene production, the method comprising the step of: topically applying to the ulcer an amount of a compound sufficient to interfere with leukotriene production and promote healing of the ulcer, the compound being selected from the group consisting of N,N'-diacetylcystine, N-acetyl homocysteine and N-acetyl cysteine.
Claim 3
Dependent Claim
18 words
The method of claim 1 wherein the compound is applied in the form of a 20% aqueous solution.
Claim 4
Dependent Claim
14 words
The method of claim 2 wherein the compound is applied four times a day.
Claim 5
Dependent Claim
17 words
The method of claim 3 wherein the compound is applied with gauze bandages soaked with the compound.
Claim 6
Dependent Claim
10 words
The method of claim 1 wherein the compound is N-acetylhomocysteine.
Claim 7
Dependent Claim
10 words
The method of claim 1 wherein the compound is N,N'-diacetylcystine.
Claim 8
Independent Claim
60 words
A method of treating chemical ulcers in warm-blooded animals which have been caused by anthracycline, the method comprising the step of: topically applying to chemical ulcers which have been caused by an anthracycline an amount of a compound sufficient to promote healing of the ulcer, the compound being selected from the group consisting of N,N'-diacetylcystine, N-acetyl homocysteine and N-acetyl cysteine.
Claim 9
Independent Claim
60 words
A method of treating chemical ulcers in warm-blooded animals which have been caused by anthracycline, the method comprising the step of: topically applying to chemical ulcers which have been caused by an anthracycline an amount of a compound sufficient to promote healing of the ulcer, the compound being selected from the group consisting of N,N'-diacetylcystine, N-acetyl homocysteine and N-acetyl cysteine.
Claim 10
Dependent Claim
18 words
The method of claim 7 wherein the compound is applied in the form of a 20% aqueous solution.
Claim 11
Dependent Claim
14 words
The method of claim 8 wherein the compound is applied four times a day.
Claim 12
Dependent Claim
17 words
The method of claim 9 wherein the compound is applied with gauze bandages soaked with the compound.
Claim 13
Dependent Claim
10 words
The method of claim 7 wherein the compound is N-acetylhomocysteine.
Claim 14
Dependent Claim
10 words
The method of claim 7 wherein the compound is N,N'-diacetylcystine.
Claim 15
Independent Claim
58 words
A method of treating chemical ulcers in warm-blooded animals which have been caused by anthracycline and which produce leukotrienes including LTA 4 , comprising the step of: forming an adduct between LTA 4 and an amount of a compound selected from the group consisting of N,N'-diacetylcystine, N-acetyl homocysteine and N-acetyl cysteine sufficient to promote healing of the ulcer.
Claim 16
Independent Claim
58 words
A method of treating chemical ulcers in warm-blooded animals which have been caused by anthracycline and which produce leukotrienes including LTA 4 , comprising the step of: forming an adduct between LTA 4 and an amount of a compound selected from the group consisting of N,N'-diacetylcystine, N-acetyl homocysteine and N-acetyl cysteine sufficient to promote healing of the ulcer.
Claim 17
Dependent Claim
10 words
The method of claim 13 wherein the compound is N-acetylhomocysteine.
Claim 18
Dependent Claim
10 words
The method of claim 13 wherein the compound is N,N'-diacetylcystine.
References Cited (Backward Citations)
US4331648A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1991-02-08 | 1991-08-10 | 1992-02-09 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1995-02-08 | 1995-08-10 | 1996-02-09 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1999-02-08 | 1999-08-10 | 2000-02-09 | $7700.00 | Window Closed / Lapsed |