US5296500A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Use of N-acetyl-cysteine and derivatives for regulating skin wrinkles and/or skin atrophy
Assignee: TEXTILE RESEARCH INSTITUTE Inc
•
Filing: 1993-07-30
•
Granted: 1994-03-22
•
Expires: 2013-07-30
Abstract
Abstract The present invention relates to a method for regulating wrinkles and/or atrophy in mammalian skin comprising treating the skin with a safe and effective amount of N-acetyl-L-cysteine and/or a derivative thereof.
Inventors
- 👤 Greg G. Hillebrand
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 12:45
CPC Classifications
A; A61; A61Q; A61Q19/00; A61K; A61K8/00; A61K8/18; A61K8/30; A61K8/40; A61K8/44; A61K8/447; A61Q19/08; A61Q17/00; A61Q17/04
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
46 words
A method for regulating wrinkles or atrophy in mammalian skin comprising treating skin in need of such regulation with a safe and effective amount of a composition comprising: a) a safe and effective amount of N-acetyl-L-cysteine or a pharmaceutically-acceptable salt thereof, and b) a pharmaceutically-acceptable carrier.
Claim 2
Independent Claim
46 words
A method for regulating wrinkles or atrophy in mammalian skin comprising treating skin in need of such regulation with a safe and effective amount of a composition comprising: a) a safe and effective amount of N-acetyl-L-cysteine or a pharmaceutically-acceptable salt thereof, and b) a pharmaceutically-acceptable carrier.
Claim 3
Dependent Claim
18 words
The method of claim 1 wherein the composition comprises from about 0.01% to about 50% of the compound.
Claim 4
Dependent Claim
18 words
The method of claim 1 wherein the composition comprises from about 0.1% to about 20% of the compound.
Claim 5
Dependent Claim
13 words
The method of claim 2 wherein the pharmaceutically-acceptable carrier is a topical carrier.
Claim 6
Dependent Claim
16 words
The method of claim 4 wherein the treatment of the skin with the composition is chronic.
Claim 7
Dependent Claim
39 words
The method of claim 5 wherein the treatment of the skin with the composition is for a period of at least about six months comprising application of the composition from about once per week to about two times daily.
Claim 8
Independent Claim
23 words
The method of any of claims 4 and 5 wherein the composition additionally comprises a safe and effective amount of a zinc salt.
Claim 9
Independent Claim
34 words
The method of any of claims 4 and 5 wherein the composition additionally comprises a zinc salt selected from the group consisting of zinc oxide, zinc stearate, zinc sulfate, zinc chloride and zinc acetate.
Claim 10
Independent Claim
23 words
The method of any of claims 4 and 5 wherein the composition additionally comprises a safe and effective amount of a sunscreening agent.
Claim 11
Independent Claim
43 words
The method of any one of claims 4 and 5 wherein the composition additionally comprises another active agent selected from the group consisting of a safe and effective amount of an anti-inflammatory agent, an anti-oxidant, a chelator, a retinoid, and a benzofuran derivative.
References Cited (Backward Citations)
DE150694C
Cited
CA75754A
Cited
US3242052A
Cited
US3591686A
Cited
US3647834A
Cited
US3749770A
Cited
US4276284A
Cited
US4016287A
Cited
FR2244541A1
Cited
US4139610A
Cited
US4132803A
Cited
US4411886A
Cited
US4331648A
Cited
US4859653A
Cited
US4876283A
Cited
US4721705A
Cited
US4711780A
Cited
JPS61289017A
Cited
GB2180153A
Cited
EP0219455A2
Cited
US4708965A
Cited
US4724239A
Cited
US4827016A
Cited
GB2192789A
Cited
GB2192790A
Cited
EP0269017A2
Cited
EP0280606A1
Cited
US4868114A
Cited
EP0304017A2
Cited
EP0339508A1
Cited
FR2651129A1
Cited
JPH03184922A
Cited
EP0440298A1
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1997-03-21 | 1997-09-20 | 1998-03-22 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2001-03-21 | 2001-09-20 | 2002-03-22 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2005-03-21 | 2005-09-20 | 2006-03-22 | $7700.00 | Window Closed / Lapsed |