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US5286730A Expired / Lapsed US ⏱️ 0.0 years remaining

Method of treating immunoinflammatory disease

Assignee: Wyeth LLC
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Filing: 1992-08-17
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Granted: 1994-02-15
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Expires: 2012-08-17
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Abstract

Abstract This invention provides a method of treating immunionflammatory skin disease in a mammal in need thereof which comprises administering an antiimmunoinflammatory amount of rapamycin, alone or in combination with cyclosporin A, orally, parenterally, intranasally, intrabronchially, topically, transdermally, or rectally. As such, rapamycin, alone or in combination with cyclosporin A, is useful in treating skin diseases such as psoriasis, atopic dermatitis, contact dermatitis, eczematous dermatitis, seborrheic dermatitis, Lichen planus, Pemphigus, bulus pemphigoid, Epidermolysis bullosa, urticaria, angioedemas, vasculitides, erythemas, cutaneous eosinphilias, and the like.

Inventors

  • 👤 Craig E. Caufield
  • 👤 John H. Musser
  • 👤 Surendra N. Sehgal

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-07 13:26
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/70; A61K38/00; A61K38/04; A61K38/12; A61K38/13; A61P; A61P1/00; A61P17/00; A61P17/06; A61P37/00

Claims Analysis

Total Claims: 8
Claim 1
Independent Claim 62 words
A method of treating an immunoinflammatory skin disease selected from the group consisting of psoriasis, atopic dermatitis, contact dermatitis, eczematous dermatitis, seborrheic dermatitis, Lichen planus, Pemphigus, bulus pemphigoid, Epidermolysis bullosa, urticaria, angioedema, vasculitide, erythema, and cutaneous eosinphiliia in a mammal in need thereof which comprises administering an antiimmunoinflammatory amount of rapamycin orally, parenterally, intranasally, intrabronchially, topically, transdermally, or rectally to said mammal.
Claim 2
Independent Claim 62 words
A method of treating an immunoinflammatory skin disease selected from the group consisting of psoriasis, atopic dermatitis, contact dermatitis, eczematous dermatitis, seborrheic dermatitis, Lichen planus, Pemphigus, bulus pemphigoid, Epidermolysis bullosa, urticaria, angioedema, vasculitide, erythema, and cutaneous eosinphiliia in a mammal in need thereof which comprises administering an antiimmunoinflammatory amount of rapamycin orally, parenterally, intranasally, intrabronchially, topically, transdermally, or rectally to said mammal.
Claim 3
Independent Claim 71 words
A method of providing symptomatic relief of, preventing the progression of, or eradicating an immunoinflammatory skin disease selected from the group consisting of psoriasis, atopic dermatitis, contact dermatitis, eczematous dermatitis, seborrheic dermatitis, Lichen planus, Pemphigus, bulus pemphigoid, Epidermolysis bullosa, urticaria, angioedema, vasculitide, erythema, and cutaneous eosinphiliia in a mammal in need thereof which comprises administering an antiimmunoinflammatory amount of rapamycin orally, parenterally, intranasally, intrabronchially, topically, transdermally, or rectally to said mammal.
Claim 4
Independent Claim 71 words
A method of providing symptomatic relief of, preventing the progression of, or eradicating an immunoinflammatory skin disease selected from the group consisting of psoriasis, atopic dermatitis, contact dermatitis, eczematous dermatitis, seborrheic dermatitis, Lichen planus, Pemphigus, bulus pemphigoid, Epidermolysis bullosa, urticaria, angioedema, vasculitide, erythema, and cutaneous eosinphiliia in a mammal in need thereof which comprises administering an antiimmunoinflammatory amount of rapamycin orally, parenterally, intranasally, intrabronchially, topically, transdermally, or rectally to said mammal.
Claim 5
Independent Claim 68 words
A method of treating an immunoinflammatory skin disease selected from the group consisting of psoriasis, atopic dermatitis, contact dermatitis, eczematous dermatitis, seborrheic dermatitis, Lichen planus, Pemphigus, bulus pemphigoid, Epidermolysis bullosa, urticaria, angioedema, vasculitide, erythema, and cutaneous esosinphiliia in a mammal in need thereof which comprises administering an antiimmunoinflammatory amount of a combination of rapamycin and cyclosporin A orally, parenterally, intranasally, intrabronchially, topically, transdermally, or rectally to said mammal.
Claim 6
Independent Claim 68 words
A method of treating an immunoinflammatory skin disease selected from the group consisting of psoriasis, atopic dermatitis, contact dermatitis, eczematous dermatitis, seborrheic dermatitis, Lichen planus, Pemphigus, bulus pemphigoid, Epidermolysis bullosa, urticaria, angioedema, vasculitide, erythema, and cutaneous esosinphiliia in a mammal in need thereof which comprises administering an antiimmunoinflammatory amount of a combination of rapamycin and cyclosporin A orally, parenterally, intranasally, intrabronchially, topically, transdermally, or rectally to said mammal.
Claim 7
Independent Claim 77 words
A method of providing symptomatic relief of, preventing the progression of, or eradicating an immunoinflammatory skin disease selected from the group consisting of psoriasis, atopic dermatitis, contact dermatitis, eczematous dermatitis, seborrheic dermatitis, Lichen planus, Pemphigus, bulus pemphigoid, Epidermolysis bullosa, urticaria, angioedema, vasculitide, erythema, and cutaneous eosinphiliia in a mammal in need thereof which comprises administering an antiimmunoinflammatory amount of a combination of rapamycin and cyclosporin A orally, parenterally, intranasally, intrabronchially, topically, transdermally, or rectally to said mammal.
Claim 8
Independent Claim 77 words
A method of providing symptomatic relief of, preventing the progression of, or eradicating an immunoinflammatory skin disease selected from the group consisting of psoriasis, atopic dermatitis, contact dermatitis, eczematous dermatitis, seborrheic dermatitis, Lichen planus, Pemphigus, bulus pemphigoid, Epidermolysis bullosa, urticaria, angioedema, vasculitide, erythema, and cutaneous eosinphiliia in a mammal in need thereof which comprises administering an antiimmunoinflammatory amount of a combination of rapamycin and cyclosporin A orally, parenterally, intranasally, intrabronchially, topically, transdermally, or rectally to said mammal.

References Cited (Backward Citations)

US3929992A Cited
US4023264A Cited
EP0315978A2 Cited
US4996193A Cited
US5023263A Cited
US5078999A Cited
US5080899A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1997-02-14 1997-08-16 1998-02-15 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2001-02-14 2001-08-16 2002-02-15 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2005-02-14 2005-08-16 2006-02-15 $7700.00 Window Closed / Lapsed

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