US5080899A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method of treating pulmonary inflammation
Assignee: Wyeth LLC
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Filing: 1991-02-22
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Granted: 1992-01-14
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Expires: 2011-02-22
Abstract
Abstract This invention provides a method of preventing or reversing pulmonary inflammation in a mammal by administering an effective amount of rapamycin orally, parenterally, intranasally, or intrabronchially. As such, rapamycin is useful in providing the symptomatic relief of diseases in which pulmonary inflammation is a component such as, asthma, chronic obstructive pulmonary disease, emphysema, acute respiratory distress syndrome, bronchitis, and the like.
Inventors
- 👤 Robert J. Sturm
- 👤 Laurel M. Adams
- 👤 Barry M. Weichman
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 18:51
CPC Classifications
A; A61; A61K; A61K35/00; A61K35/66; A61K35/74; A61K31/00; A61K31/70; A61K31/33; A61K31/395; A61K31/435; A61K31/44; A61P; A61P11/00; A61P29/00
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
30 words
A method of preventing or reversing pulmonary inflammation in a mammal in need thereof which comprises administering to said mammal an effective amount of rapamycin orally, parentally, intranasally, or intrabronchially.
Claim 2
Independent Claim
30 words
A method of preventing or reversing pulmonary inflammation in a mammal in need thereof which comprises administering to said mammal an effective amount of rapamycin orally, parentally, intranasally, or intrabronchially.
Claim 3
Dependent Claim
19 words
The method according to claim 1, which comprises administering rapamycin in a daily dose of 0.01 to 10 mg/kg.
Claim 4
Dependent Claim
19 words
The method according to claim 1, which comprises administering rapamycin in a daily dose of 0.1 to 10 mg/kg.
Claim 5
Dependent Claim
19 words
The method according to claim 1, which comprises administering rapamycin in a daily dose of 0.3 to 4 mg/kg.
Claim 6
Independent Claim
42 words
A method of providing symptomatic relief of asthma, chronic obstructive pulmonary disease, emphysema, acute respiratory distress syndrome, and acute bronchitis in a mammal in need thereof which comprises administering to said mammal an effective amount of rapamycin orally, parentally, intranasally, or intrabronchially.
Claim 7
Independent Claim
42 words
A method of providing symptomatic relief of asthma, chronic obstructive pulmonary disease, emphysema, acute respiratory distress syndrome, and acute bronchitis in a mammal in need thereof which comprises administering to said mammal an effective amount of rapamycin orally, parentally, intranasally, or intrabronchially.
Claim 8
Dependent Claim
19 words
The method according to claim 5, which comprises administering rapamycin in a daily dose of 0.01 to 10 mg/kg.
Claim 9
Dependent Claim
19 words
The method according to claim 5, which comprises administering rapamycin in a daily dose of 0.1 to 10 mg/kg.
Claim 10
Dependent Claim
19 words
The method according to claim 5, which comprises administering rapamycin in a daily dose of 0.3 to 4 mg/kg.
References Cited (Backward Citations)
US3929992A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1995-01-13 | 1995-07-15 | 1996-01-14 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1999-01-13 | 1999-07-15 | 2000-01-14 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2003-01-13 | 2003-07-15 | 2004-01-14 | $7700.00 | Window Closed / Lapsed |