US5269770A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Microcidal agent releasing catheter with balloon
Assignee: Rochester Medical Corp
•
Filing: 1992-03-13
•
Granted: 1993-12-14
•
Expires: 2012-03-13
Abstract
Abstract An elongated catheter having an interior and an exterior surface, wherein the interior surface defines a lumen passing through the catheter. The catheter further including an enclosed cavity between the interior and exterior surfaces which encircles of the lumen. The cavity having an inner wall and an outer wall, the outer wall being a resilient sleeve which can stretch generally independently of the inner wall. The cavity containing an amount of a suitable lubricating substance effective to permit the resilient sleeve to slide along an outer surface of the inner wall while in lubricated contact therewith when stretched independently of the inner wall and including a bactericidal agent, wherein the inner wall and the outer wall are joined together at distal end proximal ends of the enclosed cavity. The resilient sleeve includes a plurality of micropores which permit the bactericidal agent to diffuse into suitable aqueous environments. An automated method for producing the same, including a series of automated dipping steps, is also disclosed. A "Foley" catheter having a balloon portion and a lubricated resilient sleeve, as disclosed above, is also disclosed, as are methods for manufacturing the same.
Inventors
- 👤 Anthony J. Conway
- 👤 Philip J. Conway
- 👤 Richard D. Fryar, Jr.
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 14:51
CPC Classifications
A; A61; A61M; A61M25/00; A61M25/0043; A61M25/0045; A61M25/0009; A61M25/10; A61M25/1027; A61M25/1036; A61M2025/0056; A61M2025/0062; A61M25/1029
Claims Analysis
Total Claims: 33
Claim 1
Independent Claim
191 words
An elongated catheter comprising an interior surface and an exterior surface, said interior surfaces defining a first lumen passing through said catheter, said catheter further including an enclosed cavity between said interior and exterior surfaces which encircles a portion of said first lumen, said cavity having an inner wall and an outer wall, said outer wall being a resilient sleeve which can stretch generally independently of said inner wall, said cavity containing a bactericidal agent in a carrier substance, wherein the inner wall and the outer wall are joined together at distal and proximal ends of said cavity, and wherein said resilient sleeve includes diffusion permitting means for permitting said bactericidal agent to diffuse out of said cavity when said sleeve is in an aqueous environment, and wherein the volume of the sleeve cavity is sufficient to increase a diameter of the elongated catheter at least about five percent, wherein said catheter further includes a second lumen, an inflatable balloon and a balloon cavity, the second lumen communicating with the balloon cavity, wherein fluid can pass into the balloon cavity from the second lumen so as to inflate the inflatable balloon.
Claim 2
Dependent Claim
191 words
An elongated catheter comprising an interior surface and an exterior surface, said interior surfaces defining a first lumen passing through said catheter, said catheter further including an enclosed cavity between said interior and exterior surfaces which encircles a portion of said first lumen, said cavity having an inner wall and an outer wall, said outer wall being a resilient sleeve which can stretch generally independently of said inner wall, said cavity containing a bactericidal agent in a carrier substance, wherein the inner wall and the outer wall are joined together at distal and proximal ends of said cavity, and wherein said resilient sleeve includes diffusion permitting means for permitting said bactericidal agent to diffuse out of said cavity when said sleeve is in an aqueous environment, and wherein the volume of the sleeve cavity is sufficient to increase a diameter of the elongated catheter at least about five percent, wherein said catheter further includes a second lumen, an inflatable balloon and a balloon cavity, the second lumen communicating with the balloon cavity, wherein fluid can pass into the balloon cavity from the second lumen so as to inflate the inflatable balloon.
Claim 3
Dependent Claim
20 words
The elongated catheter of claim 1 wherein said diffusion permitting means include a plurality of micropores in said resilient sleeve.
Claim 4
Dependent Claim
45 words
The elongated catheter of claim 2 wherein said catheter is a "Foley" catheter including self-retaining means for retention of a portion of said catheter within a bladder communicating with a urethral tract of an individual requiring catheterization, said retention means including an expandable balloon portion.
Claim 5
Dependent Claim
13 words
The elongated catheter of claim 2 wherein the bactericidal agent is an antibiotic.
Claim 6
Dependent Claim
22 words
The elongated catheter of claim 4 wherein the antibiotic is selecting from the group consisting of nitrofurantoin, sulfamethoxazole, trimethoprim and mixtures thereof.
Claim 7
Dependent Claim
28 words
The elongated catheters of claim 4 wherein the carrier substance is selected from the group consisting of petrolatum, polyvinyl alcohol lubricating gels, water-soluble soaps and water-soluble bulking agents.
Claim 8
Dependent Claim
160 words
An elongated catheter comprising a tube having an inner and outer surface, said inner surface defining a first lumen, said catheter further including an enclosed sleeve cavity and an overcoat layer including resilient sleeve portion encircling the outer surface of the tube, wherein the overcoat layer is fixed to the outer surface at distal and proximal ends of the sleeve cavity, wherein the sleeve cavity is defined by the sleeve portion and a sleeve area of the outer surface proximate the sleeve portion, wherein the sleeve cavity contains a carrier substance including a bactericidal agent, and wherein the volume of the sleeve cavity is sufficient to increase a diameter of the elongated catheter at least about five percent, wherein said catheter further includes a second lumen, an inflatable balloon and a balloon cavity, the second lumen communicating with the balloon cavity, wherein fluid can pass into the balloon cavity from the second lumen so as to inflate the inflatable balloon.
Claim 9
Dependent Claim
160 words
An elongated catheter comprising a tube having an inner and outer surface, said inner surface defining a first lumen, said catheter further including an enclosed sleeve cavity and an overcoat layer including resilient sleeve portion encircling the outer surface of the tube, wherein the overcoat layer is fixed to the outer surface at distal and proximal ends of the sleeve cavity, wherein the sleeve cavity is defined by the sleeve portion and a sleeve area of the outer surface proximate the sleeve portion, wherein the sleeve cavity contains a carrier substance including a bactericidal agent, and wherein the volume of the sleeve cavity is sufficient to increase a diameter of the elongated catheter at least about five percent, wherein said catheter further includes a second lumen, an inflatable balloon and a balloon cavity, the second lumen communicating with the balloon cavity, wherein fluid can pass into the balloon cavity from the second lumen so as to inflate the inflatable balloon.
Claim 10
Dependent Claim
74 words
The elongated catheter of claim 7 wherein the carrier substance is also a lubricating substance effective to permit said resilient sleeve portion to slide along, and with respect to, the sleeve area of the outer surface while in lubricated contact therewith and when stretched independently thereof, and wherein the lubricating substance is effective to permit respective polymeric surfaces to slide generally evenly with respect to one another when in lubricated contact with each other.
Claim 11
Dependent Claim
26 words
The elongated catheter of claim 8 wherein the lubricating substance is selected from the group consisting of petrolatum, polyvinyl alcohol containing water-soluble gels, and water-soluble soaps.
Claim 12
Dependent Claim
24 words
The elongated catheter of claim 9 wherein the bactericidal agent is an antibiotic selected from the group consisting nitrofurantoin, sulfamethoxazole, trimethoprim and mixtures thereof.
Claim 13
Dependent Claim
284 words
An elongated Foley catheter for insertion into a person's body, said elongated catheter having first and second lumens and an expandable retention balloon encircling an expandable balloon cavity, said second lumen communicating with the balloon cavity, said elongated catheter made by a process comprising the steps of: (a) providing a tube having an inner surface and an outer surface, said inner surface defining a first lumen; (b) coating a first portion of the outer surface with an amount of a lubricating substance effective to generally prevent bonding tot he first portion of the outer surface and to form a coating of lubricating substance thereon, said lubricating substances including a bactericidal agent effective to reduce bacterial growth in aqueous environments; (c) coating a second portion of the outer surface and the coating of lubricating substance with a resilient polymeric bonding composition such that a resilient polymeric overcoat layer including a retention balloon is created, wherein a first segment of the overcoat layer proximate the coating of lubricating substance on the first portion of the outer surface forms a resilient sleeve which cooperates with the first portion of the outer surface define an enclosed sleeve cavity, wherein the coating of lubricating substance is contained in the sleeve cavity, and wherein the resilient sleeve can move generally independently of the first portion of the outer surface, wherein the lubricating substance is effective to permit the resilient sleeve to slide along the first portion of the outer surface while in lubricated contact therewith and when stretched independently thereof; and (d) creating a plurality of micropore in the resilient outer sleeve which permit said bactericidal agent to diffuse out said cavity when said sleeve is in an aqueous environment.
Claim 14
Dependent Claim
284 words
An elongated Foley catheter for insertion into a person's body, said elongated catheter having first and second lumens and an expandable retention balloon encircling an expandable balloon cavity, said second lumen communicating with the balloon cavity, said elongated catheter made by a process comprising the steps of: (a) providing a tube having an inner surface and an outer surface, said inner surface defining a first lumen; (b) coating a first portion of the outer surface with an amount of a lubricating substance effective to generally prevent bonding tot he first portion of the outer surface and to form a coating of lubricating substance thereon, said lubricating substances including a bactericidal agent effective to reduce bacterial growth in aqueous environments; (c) coating a second portion of the outer surface and the coating of lubricating substance with a resilient polymeric bonding composition such that a resilient polymeric overcoat layer including a retention balloon is created, wherein a first segment of the overcoat layer proximate the coating of lubricating substance on the first portion of the outer surface forms a resilient sleeve which cooperates with the first portion of the outer surface define an enclosed sleeve cavity, wherein the coating of lubricating substance is contained in the sleeve cavity, and wherein the resilient sleeve can move generally independently of the first portion of the outer surface, wherein the lubricating substance is effective to permit the resilient sleeve to slide along the first portion of the outer surface while in lubricated contact therewith and when stretched independently thereof; and (d) creating a plurality of micropore in the resilient outer sleeve which permit said bactericidal agent to diffuse out said cavity when said sleeve is in an aqueous environment.
Claim 15
Dependent Claim
111 words
The elongated catheter of claim 11 made by a process further comprising the step of stripping the lubricating substance from a third portion of the outer surface following step (b) and prior to step (c), wherein the step of coating the first portion also includes coating the third portion of the outer surface with said lubricating substance, wherein the second and third portions of the outer surface are opposite one another on either side of the first portion thereof, and wherein said overcoat layer created in step (c) is fixed to the outer surface proximate the second and third portions of the outer surface on opposite sides of the sleeve cavity.
Claim 16
Dependent Claim
198 words
An elongated catheter for insertion into an internal mammalian passageway, said elongated catheter comprising a tube having an inner and outer surface, said inner surface defining a first lumen, said catheter further comprising a cushioned sleeve wherein the cushioned sleeve includes a resilient sleeve portion and an enclosed sleeve cavity, both of which encircle the outer surface of the tube, wherein the resilient sleeve portion is joined to the outer surface at distal and proximal ends of the sleeve cavity and the sleeve cavity is defined by the sleeve portion and a sleeve area of the outer surface of the tube proximate the sleeve portion, the cushioned sleeve further including a displaceable carrier substance within said sleeve cavity, wherein the sleeve cavity of the cushioned contains an amount of displaceable carrier substance sufficient to enable the cushioned sleeve to deform outwardly along any radius from a central axis of the catheter at least about five percent, wherein said catheter further includes a second lumen, an inflatable balloon and a balloon cavity, the second lumen communicating with the balloon cavity, wherein fluid can pass into the balloon cavity from the second lumen so as to inflate the inflatable balloon.
Claim 17
Dependent Claim
198 words
An elongated catheter for insertion into an internal mammalian passageway, said elongated catheter comprising a tube having an inner and outer surface, said inner surface defining a first lumen, said catheter further comprising a cushioned sleeve wherein the cushioned sleeve includes a resilient sleeve portion and an enclosed sleeve cavity, both of which encircle the outer surface of the tube, wherein the resilient sleeve portion is joined to the outer surface at distal and proximal ends of the sleeve cavity and the sleeve cavity is defined by the sleeve portion and a sleeve area of the outer surface of the tube proximate the sleeve portion, the cushioned sleeve further including a displaceable carrier substance within said sleeve cavity, wherein the sleeve cavity of the cushioned contains an amount of displaceable carrier substance sufficient to enable the cushioned sleeve to deform outwardly along any radius from a central axis of the catheter at least about five percent, wherein said catheter further includes a second lumen, an inflatable balloon and a balloon cavity, the second lumen communicating with the balloon cavity, wherein fluid can pass into the balloon cavity from the second lumen so as to inflate the inflatable balloon.
Claim 18
Dependent Claim
48 words
The elongated catheter of claim 13, wherein said catheter further includes a second lumen, an inflatable balloon and a balloon cavity, the second lumen communicating with the balloon cavity, wherein fluid can pass into the balloon cavity from the second lumen so as to inflate the inflatable balloon.
Claim 19
Dependent Claim
32 words
The elongated catheter of claim 13 further comprising diffusion permitting means for permitting said bactericidal agent to diffuse out of said sleeve cavity when the cushioned sleeve is in an aqueous environment.
Claim 20
Dependent Claim
21 words
The elongated catheter of claim 15 wherein said diffusion permitting means include a plurality of micropores in said resilient sleeve portion.
Claim 21
Dependent Claim
13 words
The elongated catheter of claim 15 wherein the bactericidal agent is an antibiotic.
Claim 22
Dependent Claim
22 words
The elongated catheter of claim 17 wherein the antibiotic is selected from the group consisting of nitrofurantoin, sulfamethoxazole, trimethoprim and mixtures thereof.
Claim 23
Dependent Claim
171 words
An elongated catheter comprising an interior surface and an exterior surface, said interior surface defining a first lumen passing through said catheter, said catheter further including an enclosed sleeve cavity between said interior and exterior surfaces which encircles a portion of said first lumen, said sleeve cavity having an inner wall and an outer wall, said outer wall being a resilient sleeve which can stretch generally independently of said inner wall, said sleeve cavity containing a bactericidal agent in a carrier substance, wherein the inner wall and the outer wall are joined together at distal and proximal ends of said sleeve cavity, and wherein said resilient sleeve includes diffusion permitting means for permitting said bactericidal agent to diffuse out of said cavity when said sleeve is in an aqueous environment; said catheter further including a second lumen, an inflatable balloon and a balloon cavity, the second lumen communicating with the balloon cavity, wherein fluid can pass into the balloon cavity from the second lumen so as to inflate the inflatable balloon.
Claim 24
Dependent Claim
171 words
An elongated catheter comprising an interior surface and an exterior surface, said interior surface defining a first lumen passing through said catheter, said catheter further including an enclosed sleeve cavity between said interior and exterior surfaces which encircles a portion of said first lumen, said sleeve cavity having an inner wall and an outer wall, said outer wall being a resilient sleeve which can stretch generally independently of said inner wall, said sleeve cavity containing a bactericidal agent in a carrier substance, wherein the inner wall and the outer wall are joined together at distal and proximal ends of said sleeve cavity, and wherein said resilient sleeve includes diffusion permitting means for permitting said bactericidal agent to diffuse out of said cavity when said sleeve is in an aqueous environment; said catheter further including a second lumen, an inflatable balloon and a balloon cavity, the second lumen communicating with the balloon cavity, wherein fluid can pass into the balloon cavity from the second lumen so as to inflate the inflatable balloon.
Claim 25
Dependent Claim
137 words
An elongated catheter comprising a tube having an inner and outer surface, said inner surface defining a first lumen, said catheter further including an enclosed sleeve cavity and an overcoat layer including a resilient sleeve portion encircling the outer surface of the tube, wherein the overcoat layer is fixed to the outer surface at distal and proximal ends of the sleeve cavity, wherein the sleeve cavity is defined by the sleeve portion and a sleeve area of the outer surface proximate the sleeve portion, wherein the sleeve cavity contains a carrier substance including a bactericidal agent; said catheter further including a second lumen, an inflatable balloon and a balloon cavity, the second lumen communicating with the balloon cavity, wherein fluid can pass into the balloon cavity from the second lumen so as to inflate the inflatable balloon.
Claim 26
Dependent Claim
137 words
An elongated catheter comprising a tube having an inner and outer surface, said inner surface defining a first lumen, said catheter further including an enclosed sleeve cavity and an overcoat layer including a resilient sleeve portion encircling the outer surface of the tube, wherein the overcoat layer is fixed to the outer surface at distal and proximal ends of the sleeve cavity, wherein the sleeve cavity is defined by the sleeve portion and a sleeve area of the outer surface proximate the sleeve portion, wherein the sleeve cavity contains a carrier substance including a bactericidal agent; said catheter further including a second lumen, an inflatable balloon and a balloon cavity, the second lumen communicating with the balloon cavity, wherein fluid can pass into the balloon cavity from the second lumen so as to inflate the inflatable balloon.
Claim 27
Dependent Claim
201 words
An elongated catheter for insertion into an internal mammalian passageway, said elongated catheter comprising a tube having an inner and outer surface, said inner surface defining a first lumen, said catheter further comprising a cushioned sleeve, the cushioned sleeve including a resilient sleeve portion and an enclosed sleeve cavity which encircle the outer surface of the tube, wherein the resilient sleeve portion is joined to the outer surface at distal and proximal ends of the sleeve cavity and the sleeve cavity is defined by the sleeve portion and a sleeve area of the outer surface of the tube proximate the sleeve portion, the cushioned sleeve further including a displaceable carrier substance within said sleeve cavity, the carrier substance including a bactericidal agent, the sleeve cavity of the cushioned sleeve containing an amount of displaceable carrier substance sufficient to enable the cushioned sleeve to deform outwardly along any radius form a central axis of the catheter at least about five percent; said catheter further including a second lumen, an inflatable balloon and a balloon cavity, the second lumen communicating with the balloon cavity, wherein fluid can pass into the balloon cavity from the second lumen so as to inflate the inflatable balloon.
Claim 28
Dependent Claim
201 words
An elongated catheter for insertion into an internal mammalian passageway, said elongated catheter comprising a tube having an inner and outer surface, said inner surface defining a first lumen, said catheter further comprising a cushioned sleeve, the cushioned sleeve including a resilient sleeve portion and an enclosed sleeve cavity which encircle the outer surface of the tube, wherein the resilient sleeve portion is joined to the outer surface at distal and proximal ends of the sleeve cavity and the sleeve cavity is defined by the sleeve portion and a sleeve area of the outer surface of the tube proximate the sleeve portion, the cushioned sleeve further including a displaceable carrier substance within said sleeve cavity, the carrier substance including a bactericidal agent, the sleeve cavity of the cushioned sleeve containing an amount of displaceable carrier substance sufficient to enable the cushioned sleeve to deform outwardly along any radius form a central axis of the catheter at least about five percent; said catheter further including a second lumen, an inflatable balloon and a balloon cavity, the second lumen communicating with the balloon cavity, wherein fluid can pass into the balloon cavity from the second lumen so as to inflate the inflatable balloon.
Claim 29
Dependent Claim
32 words
The elongated catheter of claim 21 further comprising diffusion permitting means for permitting said bactericidal agent to diffuse out of said sleeve cavity when the cushioned sleeve is in an aqueous environment.
Claim 30
Dependent Claim
21 words
The elongated catheter of claim 22 wherein said diffusion permitting means include a plurality of micropores in said resilient sleeve portion.
Claim 31
Dependent Claim
13 words
The elongated catheter of claim 23 wherein the bactericidal agent is an antibiotic.
Claim 32
Dependent Claim
22 words
The elongated catheter of claim 24 wherein the antibiotic is selected from the group consisting of nitrofurantoin, sulfamethoxazole, trimethoprim and mixtures thereof.
Claim 33
Dependent Claim
28 words
The elongated catheter of claim 25 wherein the carrier substance is selected from the group consisting of petrolatum, polyvinyl alcohol lubricating gels, water-soluble soaps and water-soluble bulking agents.
References Cited (Backward Citations)
CA763930A
Cited
US2043630A
Cited
US2330399A
Cited
US2314262A
Cited
US2330400A
Cited
US2248934A
Cited
US2230226A
Cited
US2308484A
Cited
US2322858A
Cited
US2390070A
Cited
US2481488A
Cited
US2690595A
Cited
US2712161A
Cited
US3304353A
Cited
US3169527A
Cited
US3875937A
Cited
US3394704A
Cited
US3598127A
Cited
US3593713A
Cited
US3544668A
Cited
US3539674A
Cited
US3566874A
Cited
US3556294A
Cited
US3606889A
Cited
US3683928A
Cited
US3708324A
Cited
US3695921A
Cited
US3699956A
Cited
US3981299A
Cited
US3879516A
Cited
US3894540A
Cited
US3854483A
Cited
US4062363A
Cited
US3889685A
Cited
US4029104A
Cited
FR2351634A1
Cited
US4133303A
Cited
US4149539A
Cited
US4196731A
Cited
US4198984A
Cited
US4284459A
Cited
US4381008A
Cited
US4249535A
Cited
US4269310A
Cited
US4479795A
Cited
US4472226A
Cited
US4318947A
Cited
US4381380A
Cited
EP0055023A2
Cited
US4539234A
Cited
US4515593A
Cited
US4571239A
Cited
WO1984001102A1
Cited
US4769013A
Cited
US4634433A
Cited
US4603152A
Cited
JPS59218157A
Cited
US4592920A
Cited
JPS59228856A
Cited
US4571240A
Cited
US4820292A
Cited
US4747845A
Cited
US4563184A
Cited
US4582762A
Cited
US4863424A
Cited
GB2150938B
Cited
US4686124A
Cited
US4623329A
Cited
US4692152A
Cited
US4652259A
Cited
US4581028A
Cited
US4968507A
Cited
US4622033A
Cited
US4677143A
Cited
US4737219A
Cited
US4612337A
Cited
US4710181A
Cited
US4601713A
Cited
US4664657A
Cited
US4863444A
Cited
US4627844A
Cited
US4687470A
Cited
US4917686A
Cited
US4838876A
Cited
US4772473A
Cited
US4775371A
Cited
US4923450A
Cited
US4935260A
Cited
US4904260A
Cited
US4850969A
Cited
US4902503A
Cited
US5019601A
Cited
US5019378A
Cited
US5019096A
Cited
US4976703A
Cited
US4950256A
Cited
US5013717A
Cited
US4994047A
Cited
US5013306A
Cited
US4925668A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1996-12-13 | 1997-06-14 | 1997-12-14 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2000-12-13 | 2001-06-14 | 2001-12-14 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2004-12-13 | 2005-06-14 | 2005-12-14 | $7700.00 | Window Closed / Lapsed |