US4863444A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Antibiotic-containing agent and its use as a surgical plastic material
Assignee: Individual
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Filing: 1989-02-10
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Granted: 1989-09-05
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Expires: 2009-02-10
Abstract
Abstract It is known that antibiotics, particularly gentamycine, are released with delay from plastic materials such as polymethacrylate and/or polyacrylate. Thereby, a steep initial decrease in concentration long periods of time. These antibiotic-containing synthetic materials have been used heretofore as bone cement, for the fastening of endoprostheses or in the, for instance of total endoprostheses of the hip or in the replacement of infected endoprostheses. To combat and prevent infection, the antibiotics are added prior to the polymerization of the synthetic material. The invention has the object to create. In accordance with the invention, it is the carrier (2) be shaped like a stick. The carrier (2) can also have the shape of a cylinder, with a central passage duct (4) provided in its longitudinal direction. The carrier (2) is provided with a plurality of radial openings (3), which communicate with a central passage duct (4).
Inventors
- 👤 Alois Blomer
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 22:42
CPC Classifications
A; A61; A61B; A61B17/00; A61B17/56; A61B17/58; A61B17/68; A61B17/60; A61L; A61L31/00; A61L31/14; A61L31/16; A61B17/84; A61B17/846; A61B17/848; A61F; A61F2/00; A61F2/02; A61F2/30; A61F2002/30001; A61F2002/30667; A61F2002/30677; A61L2300/00; A61L2300/40; A61L2300/404; A61L2300/406
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
101 words
Antibiotic delivery article comprising: a carrier in the form of a hollow elongate cylinder fabricated from a plastic material; a central passage duct within said cylinder aligned along a longitudinal axis thereof; a plurality of radial outlet openings formed in said carrier distributed over an entire length of said carrier and leading to an outer surface thereof, said openings communicating with said central passage duct; an antibiotic agent evenly and releasably distributed within said carrier; and a fixation means selected from the group consisting of nails, pins and screws inserted into and traversing a full length of said central passage duct.
Claim 2
Dependent Claim
101 words
Antibiotic delivery article comprising: a carrier in the form of a hollow elongate cylinder fabricated from a plastic material; a central passage duct within said cylinder aligned along a longitudinal axis thereof; a plurality of radial outlet openings formed in said carrier distributed over an entire length of said carrier and leading to an outer surface thereof, said openings communicating with said central passage duct; an antibiotic agent evenly and releasably distributed within said carrier; and a fixation means selected from the group consisting of nails, pins and screws inserted into and traversing a full length of said central passage duct.
Claim 3
Dependent Claim
26 words
An article according to claim 1 wherein the plastic material is formed from a polymer selected from the group consisting of polymethacrylate, polyacrylate and mixtures thereof.
Claim 4
Dependent Claim
11 words
An article according to claim 1 wherein said antibiotic is gentamycin.
Claim 5
Independent Claim
134 words
A method for combatting infection arising from external fixtures, that includes fixation means selected from the group consisting of nails, pins and screws, inserted into a part of a human body, the method comprising surrounding said fixation means over a full length thereof by a carrier in the form of a hollow elongate cylinder fabricated from a plastic material, said carrier having a central passage duct aligned along a longitudinal axis of the carrier, a plurality of radial outlet openings formed in said carrier distributed over an entire length of said carrier and leading to an outer surface thereof wherein said openings communicate with said central passage duct, and an antibiotic agent evenly and releasably distributed within said carrier and disposing said carrier around said fixation means in said part of said human body.
Claim 6
Independent Claim
134 words
A method for combatting infection arising from external fixtures, that includes fixation means selected from the group consisting of nails, pins and screws, inserted into a part of a human body, the method comprising surrounding said fixation means over a full length thereof by a carrier in the form of a hollow elongate cylinder fabricated from a plastic material, said carrier having a central passage duct aligned along a longitudinal axis of the carrier, a plurality of radial outlet openings formed in said carrier distributed over an entire length of said carrier and leading to an outer surface thereof wherein said openings communicate with said central passage duct, and an antibiotic agent evenly and releasably distributed within said carrier and disposing said carrier around said fixation means in said part of said human body.
Claim 7
Dependent Claim
26 words
A method according to claim 4 wherein the plastic material is formed from a polymer selected from the group consisting of polymethacrylate, polyacrylate and mixtures thereof.
Claim 8
Dependent Claim
11 words
A method according to claim 4 wherein said antibiotic is gentamycin.
References Cited (Backward Citations)
US3695921A
Cited
US3805300A
Cited
US3882858A
Cited
US3987497A
Cited
US4191743A
Cited
US4297993A
Cited
DE2815934A1
Cited
US4373217A
Cited
US4329743A
Cited
EP0022289A1
Cited
US4455690A
Cited
CA1183776A
Cited
US4731054A
Cited
US4708132A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-09-04 | 1993-03-06 | 1993-09-05 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-09-04 | 1997-03-06 | 1997-09-05 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-09-04 | 2001-03-06 | 2001-09-05 | $7700.00 | Window Closed / Lapsed |