US5260319A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Thienobenzoxepins and naphthothiophenes
Assignee: Aventis Pharmaceuticals Inc
•
Filing: 1993-03-19
•
Granted: 1993-11-09
•
Expires: 2013-03-19
Abstract
Abstract Novel thienobenzoxepins and naphthothiophenes, intermediates and processes for the preparation thereof, and methods of alleviating pain utilizing compounds or compositions thereof are disclosed.
Inventors
- 👤 Richard C. Effland
- 👤 David G. Wettlaufer
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 07:18
CPC Classifications
C; C07; C07D; C07D409/00; C07D409/02; C07D409/04; C07D409/06; C07D495/00; C07D495/02; C07D495/04
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
46 words
A compound of the formula ##STR6## wherein R is loweralkyl or arylloweralkyl; X and Y are independently hydrogen, loweralkyl, halogen, loweralkoxy, or trifluoromethyl; W is CH 2 , CHOH, or C═O; and n is 1 or 2; an optical isomer or pharmaceutically acceptable addition salt thereof.
Claim 2
Dependent Claim
46 words
A compound of the formula ##STR6## wherein R is loweralkyl or arylloweralkyl; X and Y are independently hydrogen, loweralkyl, halogen, loweralkoxy, or trifluoromethyl; W is CH 2 , CHOH, or C═O; and n is 1 or 2; an optical isomer or pharmaceutically acceptable addition salt thereof.
Claim 3
Dependent Claim
10 words
A compound according to claim 1 wherein n is 2.
Claim 4
Dependent Claim
9 words
The compound according to claim 2 which is (2-fluorophenyl)[3-[(1-methyl-4-piperidinyl)hydroxymethyl]-2-thienyl]methanone.
Claim 5
Dependent Claim
9 words
The compound according to claim 2 which is α-[2-[(2-fluorophenyl)methyl]-3-thienyl]-1-methyl-4-piperidinemethanol.
Claim 6
Dependent Claim
13 words
The compound according to claim 2 which is α 2 -(2-fluorophenyl)-α 3 -(1-methyl-4-piperidinyl)-2,3-thiophenedimethanol.
Claim 7
Dependent Claim
29 words
A method of alleviating pain in a mammal by administering to a mammal in need of pain alleviation a pain alleviating effect amount of a compound of claim 1.
Claim 8
Dependent Claim
20 words
A composition comprising a pain alleviating effective amount of a compound of claim 1 and a pharmaceutically acceptable adjuvant therefor.
References Cited (Backward Citations)
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1996-11-08 | 1997-05-10 | 1997-11-09 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2000-11-08 | 2001-05-10 | 2001-11-09 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2004-11-08 | 2005-05-10 | 2005-11-09 | $7700.00 | Window Closed / Lapsed |