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US4595689A Expired / Lapsed US ⏱️ 0.0 years remaining

4-(8-bromodibenz[b,f]oxepin-10-yl)-1,2,3,6-tetrahydro-1-methylpyridine and 4-(2-bromodibenzo[a,d]cyclophetatriene-11-yl)-1,2,3,6-tetrahydro-1-methylpyridine for dermal inflammation

Assignee: Hoffmann La Roche Inc
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Filing: 1984-02-09
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Granted: 1986-06-17
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Expires: 2004-02-09
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Abstract

Abstract A method of treating inflammation which comprises topically administering to the affected area a compound of the formula <IMAGE> or <IMAGE> or a pharmaceutically acceptable addition salt thereof, is described.

Inventors

  • 👤 Alfred Boris
  • 👤 Robert W. Guthrie
  • 👤 Richard W. Kierstead

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-24 07:18
CPC Classifications
C; C07; C07D; C07D405/00; C07D405/02; C07D405/04; C07D211/00; C07D211/04; C07D211/68; C07D211/70

Claims Analysis

Total Claims: 5
Claim 1
Independent Claim 35 words
A method for treating dermal inflammation which comprises topically administering to the affected area an effective amount of a compound selected from the group consisting of 4-(8-bromodibenz[b,f]oxepin-10-yl)-1,2,3,6-tetrahydro-1-methylpyridine, 4-(2-bromodibenzo[a,d]cycloheptatriene-11-yl)-1,2,3,6-tetrahydro-1-methylpyridine or a pharmaceutically acceptable addition salt thereof.
Claim 2
Independent Claim 35 words
A method for treating dermal inflammation which comprises topically administering to the affected area an effective amount of a compound selected from the group consisting of 4-(8-bromodibenz[b,f]oxepin-10-yl)-1,2,3,6-tetrahydro-1-methylpyridine, 4-(2-bromodibenzo[a,d]cycloheptatriene-11-yl)-1,2,3,6-tetrahydro-1-methylpyridine or a pharmaceutically acceptable addition salt thereof.
Claim 3
Dependent Claim 12 words
The method in accordance with claim 1, wherein the compound is 4-(2-bromodibenzo[a,d]cycloheptatriene-11-yl)-1,2,3,6-tetrahydro-1-methylpyridine.
Claim 4
Dependent Claim 12 words
The method in accordance with claim 1 wherein the compound is 4-(8-bromodibenz[b,f]oxepin-10-yl)-1,2,3,6-tetrahydro-1-methylpyridine.
Claim 5
Dependent Claim 18 words
The method in accordance with claim 1, wherein the pharmaceutically acceptable addition salt is 4-(8-bromodibenz[b,f]oxepin-10-yl)-1,2,3,6-tetrahydro-1-methylpyridine, (Z)-2-butenedioate (1:1) salt.

References Cited (Backward Citations)

US3479356A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1989-06-16 1989-12-16 1990-06-17 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1993-06-16 1993-12-16 1994-06-17 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1997-06-16 1997-12-16 1998-06-17 $7700.00 Window Closed / Lapsed

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