Patent US5137534A successfully refreshed from Google Patents.
US5137534A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method for producing dental and medical bone prosthesis and bone prosthesis produced thereby
Assignee: Pentax Corp
•
Filing: 1991-04-25
•
Granted: 1992-08-11
•
Expires: 2011-04-25
Abstract
Abstract A method for producing a dental and medical bone prosthesis comprising the step of: adding an aqueous acidic solution of an organic or inorganic acid, such as phosphoric acid, citric acid, or acetic acid, to a fixable granulated bone prosthesis comprising at least one of α-tricalcium phosphate and tetracalcium phosphate; and a dental and medical bone prosthesis produced thereby.
Inventors
- 👤 Masaya Sumita
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-05 04:17
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/02; A61L27/12; A61F; A61F2/00; A61F2/02; A61F2/28; A61F2310/00; A61F2310/00005; A61F2310/00179; A61F2310/00293; A61L2430/00; A61L2430/02; Y; Y10; Y10S; Y10S623/00; Y10S623/915; Y10S623/919
Claims Analysis
Total Claims: 25
Claim 1
Independent Claim
75 words
A method for producing a dental and medical bone prosthesis comprising the step of: adding an aqueous acidic solution to a fixable granulated bone prosthesis comprising particles comprising at least one compound selected from the group consisting of α-tricalcium phosphate and tetracalcium phosphate, wherein said particles have a particle diameter of 200 μm or more, and wherein said aqueous acidic solution is sufficiently acidic to fuse said granules to each other by a hydration reaction.
Claim 2
Independent Claim
75 words
A method for producing a dental and medical bone prosthesis comprising the step of: adding an aqueous acidic solution to a fixable granulated bone prosthesis comprising particles comprising at least one compound selected from the group consisting of α-tricalcium phosphate and tetracalcium phosphate, wherein said particles have a particle diameter of 200 μm or more, and wherein said aqueous acidic solution is sufficiently acidic to fuse said granules to each other by a hydration reaction.
Claim 3
Dependent Claim
47 words
A method for producing a dental and medical bone prosthesis as claimed in claim 1, wherein the ratio of the total amount of α-tricalcium phosphate and tetracalcium phosphate to the total amount of other components in said fixable granulated bone prosthesis is 1:3 by weight or more.
Claim 4
Dependent Claim
31 words
A method for producing a dental and medical bone prosthesis as claimed in claim 1, wherein said fixable granulated bone prosthesis further comprises at least one of hydroxyapatite and β-tricalcium phosphate.
Claim 5
Dependent Claim
80 words
A method for producing a dental and medical bone prosthesis as claimed in claim 1, wherein said fixable granulated bone prosthesis comprises a material selected from the group consisting of (1) α-tricalcium phosphate, (2) tetracalcium phosphate, (3) a mixture of α-tricalcium phosphate and tetracalcium phosphate, (4) a mixture of α-tricalcium phosphate and hydroxyapatite, (5) a mixture of tetracalcium phosphate and hydroxyapatite, (6) a mixture of tetracalcium phosphate and β-tricalcium phosphate, and (7) a mixture of α-tricalcium phosphate and β-tricalcium phosphate.
Claim 6
Dependent Claim
71 words
A method for producing a dental and medical bone prosthesis as claimed in claim 4, wherein said fixable granulated bone prosthesis comprises (3) a mixture of α-tricalcium phosphate and tetracalcium phosphate which is produced by the step of calcining, at a temperature of from about 1,150° C. to 1,450° C. under reduced pressure, a calcium phosphate having a molar ratio of Ca/P of about 1.8 or less and more than 1.5.
Claim 7
Dependent Claim
64 words
A method for producing a dental and medical bone prosthesis as claimed in claim 4, wherein said fixable granulated bone prosthesis comprises (4) a mixture of α-tricalcium phosphate and hydroxyapatite which is produced by the step of calcining, at a temperature of about 1,000° C. or more, a calcium phosphate having a molar ratio of Ca/P of less than 1.67 and more than 1.5.
Claim 8
Dependent Claim
64 words
A dental and medical bone prosthesis produced by a process comprising mixing granules comprising at least one compound selected from the group consisting of α-tricalcium phosphate and tetracalcium phosphate with an aqueous acidic solution, said aqueous acidic solution being sufficiently acidic to fuse said granules to each other by a hydration reaction, wherein said granules have a particle diameter of 200 μm or more.
Claim 9
Dependent Claim
64 words
A dental and medical bone prosthesis produced by a process comprising mixing granules comprising at least one compound selected from the group consisting of α-tricalcium phosphate and tetracalcium phosphate with an aqueous acidic solution, said aqueous acidic solution being sufficiently acidic to fuse said granules to each other by a hydration reaction, wherein said granules have a particle diameter of 200 μm or more.
Claim 10
Dependent Claim
28 words
A dental and medical bone prosthesis as claimed in claim 7, wherein said granulated bone prosthesis has an average particle diameter of from 200 μm to 5 mm.
Claim 11
Dependent Claim
29 words
A dental and medical bone prosthesis as claimed in claim 8, wherein said fixable granulated bone prosthesis has an average particle diameter of from 300 μm to 1 mm.
Claim 12
Dependent Claim
40 words
A method for producing a dental and medical bone prosthesis as claimed in claim 1, wherein said fixable granulated bone prosthesis is made porous upon (a) adding a foaming agent or a substance which disappears upon calcining, and (b) calcining.
Claim 13
Dependent Claim
28 words
A method for producing a dental and medical bone prosthesis as claimed in claim 1, wherein said aqueous acidic solution is an aqueous solution of an organic acid.
Claim 14
Dependent Claim
35 words
A method for producing a dental and medical bone prosthesis as claimed in claim 11, wherein said organic acid is selected from the group consisting of acetic acid, citric acid, malic acid and lactic acid.
Claim 15
Dependent Claim
22 words
A method for producing a dental and medical bone prosthesis as claimed in claim 12, wherein said organic acid is citric acid.
Claim 16
Independent Claim
71 words
A method for producing a dental and medical bone prosthesis comprising the step of: adding an aqueous acidic solution to a fixable granulated bone prosthesis comprising particles comprising at least one compound selected from the group consisting of α-tricalcium phosphate and tetracalcium phosphate, wherein said particles have a particle diameter of 200 μm or more, and wherein said aqueous acidic solution has an acid concentration of 30 wt % or more.
Claim 17
Independent Claim
71 words
A method for producing a dental and medical bone prosthesis comprising the step of: adding an aqueous acidic solution to a fixable granulated bone prosthesis comprising particles comprising at least one compound selected from the group consisting of α-tricalcium phosphate and tetracalcium phosphate, wherein said particles have a particle diameter of 200 μm or more, and wherein said aqueous acidic solution has an acid concentration of 30 wt % or more.
Claim 18
Dependent Claim
31 words
A method for producing a dental and medical bone prosthesis as claimed in claim 14, wherein said aqueous acidic solution has an acid concentration of from 40 to 55 wt %.
Claim 19
Dependent Claim
36 words
A method for producing a dental and medical bone prosthesis as claimed in claim 1, wherein the amount ratio of said granulated bone prosthesis to said aqueous acidic solution is from 1 to 20 by weight.
Claim 20
Dependent Claim
36 words
A method for producing a dental and medical bone prosthesis as claimed in claim 16, wherein the amount ratio of said granulated bone prosthesis to said aqueous acidic solution is from 1 to 5 by weight.
Claim 21
Dependent Claim
45 words
A method for producing a dental and medical bone prosthesis as claimed in claim 1, and wherein said aqueous acidic solution is added to said fixable granulated bone prosthesis either after or immediately before said granulated bone prosthesis is used to fill a bone defect.
Claim 22
Dependent Claim
61 words
A dental and medical bone prosthesis produced by the method comprising the step of: adding an aqueous acidic solution to a fixable granulated bone prosthesis comprising at least one compound selected from the group consisting of α-tricalcium phosphate and tetracalcium phosphate, and wherein said aqueous acidic solution is sufficiently acidic to fuse said granules to each other by a hydration reaction.
Claim 23
Dependent Claim
61 words
A dental and medical bone prosthesis produced by the method comprising the step of: adding an aqueous acidic solution to a fixable granulated bone prosthesis comprising at least one compound selected from the group consisting of α-tricalcium phosphate and tetracalcium phosphate, and wherein said aqueous acidic solution is sufficiently acidic to fuse said granules to each other by a hydration reaction.
Claim 24
Independent Claim
75 words
A method of fixing a granulated bone prosthesis comprising adding an aqueous acidic solution to said granulated bone prosthesis, wherein said granulated bone prosthesis comprises particles comprising at least one compound selected from the group consisting of α-tricalcium phosphate and tetracalcium phosphate, said particles having a particle diameter of from 200 μm to 5 mm, and wherein said aqueous acidic solution is sufficiently acidic to fuse said granules to each other by a hydration reaction.
Claim 25
Independent Claim
75 words
A method of fixing a granulated bone prosthesis comprising adding an aqueous acidic solution to said granulated bone prosthesis, wherein said granulated bone prosthesis comprises particles comprising at least one compound selected from the group consisting of α-tricalcium phosphate and tetracalcium phosphate, said particles having a particle diameter of from 200 μm to 5 mm, and wherein said aqueous acidic solution is sufficiently acidic to fuse said granules to each other by a hydration reaction.
References Cited (Backward Citations)
DE2008010A1
Cited
US4610692A
Cited
DE3424292A1
Cited
GB2142915A
Cited
JPS6183107A
Cited
US4677140A
Cited
EP0166263A1
Cited
JPS619265A
Cited
US4668295A
Cited
US4693986A
Cited
JPS62281953A
Cited
JPS6330361A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1995-08-11 | 1996-02-10 | 1996-08-11 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1999-08-11 | 2000-02-10 | 2000-08-11 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2003-08-11 | 2004-02-10 | 2004-08-11 | $7700.00 | Window Closed / Lapsed |