Patent US5124103A successfully refreshed from Google Patents.
US5124103A
Expired / Lapsed
US
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Two phase compositions for absorbable surgical devices
Assignee: United States Surgical Corp
•
Filing: 1990-08-02
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Granted: 1992-06-23
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Expires: 2010-08-02
Abstract
Abstract An absorbable, annealed surgical device made from a multi-phase, polymeric composition derived from lactide and glycolide. Preferably, the composition has two phases, both phases are continuous, the first phase has about 0-about 25%m glycolide moieties, the overall composition has up to 45%m glycolide moieties, and the first phase constitutes at least 50% (and preferably not more than about 95%) by weight of the composition. The device has a high distortion temperature, good resistance to hot-wet creep, but yet loses tensile strength in vivo quickly. The composition per se is injection-moldable, can be annealed, and is not brittle.
Inventors
- 👤 Donald S. Kaplan
- 👤 Matthew E. Hermes
- 👤 Ross R. Muth
- 👤 John J. Kennedy
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 23:13
CPC Classifications
A; A61; A61L; A61L31/00; A61L31/04; A61L31/041; A61L31/12; A61L31/125; A61L31/129
Claims Analysis
Total Claims: 13
Claim 1
Independent Claim
118 words
A process of molding an absorbable surgical article comprising the steps of: providing a dry two-phase polymer composition comprising a glycolide-rich polymer dispersed in a matrix of a lactide-rich polymer, the overall composition having a predominant amount of lactide moieties; placing the composition in a first hopper; applying a vacuum to and slowly heating the composition within the first hopper to maintain the composition in a dry condition; thereafter passing the dried two phase polymeric composition into a second hopper after the composition has been heated in the first hopper; feeding the dried two phase polymeric composition from the second hopper to an injection molding apparatus; and injecting the composition into a mold and recovering the molded article.
Claim 2
Dependent Claim
118 words
A process of molding an absorbable surgical article comprising the steps of: providing a dry two-phase polymer composition comprising a glycolide-rich polymer dispersed in a matrix of a lactide-rich polymer, the overall composition having a predominant amount of lactide moieties; placing the composition in a first hopper; applying a vacuum to and slowly heating the composition within the first hopper to maintain the composition in a dry condition; thereafter passing the dried two phase polymeric composition into a second hopper after the composition has been heated in the first hopper; feeding the dried two phase polymeric composition from the second hopper to an injection molding apparatus; and injecting the composition into a mold and recovering the molded article.
Claim 3
Dependent Claim
20 words
The process of claim 1 wherein the pressure in said first hopper is no higher than about 5 m Hg.
Claim 4
Dependent Claim
20 words
The process of claim 1 wherein he pressure in said first hopper is no higher than about 0.1 mm Hg.
Claim 5
Dependent Claim
18 words
The process of claim 1 wherein the composition is maintained in said first hopper for about 15 hours.
Claim 6
Dependent Claim
27 words
The process according of claim 1 wherein the composition is maintained in said first hopper at an elevated temperature under vacuum for at least about one hour.
Claim 7
Dependent Claim
14 words
The process of claim 5 wherein the elevated temperature is 50° to 70° C.
Claim 8
Dependent Claim
28 words
The process of claim 5 wherein the injection molding is carried out at a temperature less than the melting point of the polymer of the glycolide rich phase.
Claim 9
Dependent Claim
26 words
The process of claim 5 wherein said first hopper, said second hopper and said injection molding apparatus are padded or purged with a dry inert gas.
Claim 10
Dependent Claim
13 words
The process according to claim 1 wherein the second hopper is under vacuum.
Claim 11
Dependent Claim
17 words
The process of claim 1 wherein the first hopper is heated to 50° to 70 ° C.
Claim 12
Dependent Claim
11 words
The process of claim 1, wherein the second hopper is preheated.
Claim 13
Dependent Claim
13 words
The process of claim 1, wherein the second hopper is not under vacuum.
References Cited (Backward Citations)
US2703316A
Cited
US2668162A
Cited
US2758987A
Cited
GB779291A
Cited
US3225766A
Cited
US3268486A
Cited
US3739773A
Cited
US3297033A
Cited
US3875937A
Cited
US3620218A
Cited
US3463158A
Cited
US3268487A
Cited
US3531561A
Cited
US3442871A
Cited
US3422181A
Cited
US3468853A
Cited
US3597449A
Cited
US3626948A
Cited
US3772420A
Cited
US3565869A
Cited
US3773919A
Cited
US3797499A
Cited
US3636956A
Cited
GB1332505A
Cited
US3846382A
Cited
US3781349A
Cited
US3878284A
Cited
US3736646A
Cited
US3867190A
Cited
US3784585A
Cited
US3839297A
Cited
US3792010A
Cited
US3982543A
Cited
US4033938A
Cited
GB1414600A
Cited
US3902497A
Cited
US4128612A
Cited
US3896802A
Cited
US3937223A
Cited
US4027676A
Cited
US4045418A
Cited
US4057537A
Cited
US4014433A
Cited
US4060089A
Cited
US4201216A
Cited
US4300565A
Cited
US4137921A
Cited
US4157437A
Cited
US4279249A
Cited
US4243775A
Cited
US4246904A
Cited
US4275813A
Cited
US4273920A
Cited
US4412804A
Cited
US4490326A
Cited
GB2102827A
Cited
US4591630A
Cited
US4449531A
Cited
US4402445A
Cited
US4636084A
Cited
US4444927A
Cited
US4523591A
Cited
US4578455A
Cited
US4591467A
Cited
US4650488A
Cited
US4671280A
Cited
US4741337A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1995-06-23 | 1995-12-23 | 1996-06-23 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1999-06-23 | 1999-12-23 | 2000-06-23 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2003-06-23 | 2003-12-23 | 2004-06-23 | $7700.00 | Window Closed / Lapsed |