Electrical transdermal drug applicator with counteractor and method of drug delivery

Claim 1

A transdermal drug patch for delivering at least one drug to the bloodstream of a patient over an extended period of time comprising: reservoir means for containing one or more therapeutic drugs to be applied to the bloodstream of a patient through the skin thereof, a source of DC potential having a return electrode connected to one polarity terminal thereof and said reservoir means connected to an opposite polarity terminal thereof forming an electrical series circuit when the reservoir means and return electrode are applied to the skin of the patient and interface therewith, means for operating the electrical circuit in different operational cycles to effect application of the therapeutic drug or drugs into the bloodstream of the patient through the skin by electrokinetic processes including electrophoresis and electro-osmosis in dependence upon the drug to be administered to the patient, and for at the same time electrically and electrochemically maintaining the negative surface charge density of the blood vessel walls and blood cells of the patient and effecting vasodilation of the vascular system of the patient at least in a region where the transdermal patch is attached to the skin of the patient.