Patent US5034375A successfully refreshed from Google Patents.
US5034375A
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Process of wound healing using PDGF and EGF
Assignee: Biomimetic Therapeutics LLC
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Filing: 1988-08-10
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Granted: 1991-07-23
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Expires: 2008-08-10
Abstract
Abstract Healing an external wound of a mammal by administering to the mammal a composition containing purified EGF and purified PDGF in a weight to weight ratio of at least 5:1.
Inventors
- 👤 Harry N. Antoniades
- 👤 Samuel E. Lynch
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 17:49
CPC Classifications
A; A61; A61K; A61K38/00; A61K38/16; A61K38/17; A61K38/18; A61K38/1808; A61P; A61P17/00; A61P43/00
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
54 words
A method for healing an external wound of a mammal comprising applying to said wound a wound-healing amount of a composition consisting essentially of purified epidermal growth factor (EGF) and purified platelet-derived growth factor (PDGF) wherein said EGF and said PDGF are present in a weight to weight ratio of at least 5:1, respectively.
Claim 2
Independent Claim
54 words
A method for healing an external wound of a mammal comprising applying to said wound a wound-healing amount of a composition consisting essentially of purified epidermal growth factor (EGF) and purified platelet-derived growth factor (PDGF) wherein said EGF and said PDGF are present in a weight to weight ratio of at least 5:1, respectively.
Claim 3
Dependent Claim
24 words
The method of claim 1 wherein the weight to weight ratio of said EGF to said PDGF in said composition is at lest 10:1.
Claim 4
Independent Claim
58 words
A method of healing an external wound of a mammal comprising applying to said wound a wound-healing amount of a composition consisting essentially of purified PDGF and purified EGF in a weight-to-weight ratio of at least 5:1, wherein said EGF is present in said composition at a concentration of at least 500 ng/150 mm 2 in said wound.
Claim 5
Independent Claim
58 words
A method of healing an external wound of a mammal comprising applying to said wound a wound-healing amount of a composition consisting essentially of purified PDGF and purified EGF in a weight-to-weight ratio of at least 5:1, wherein said EGF is present in said composition at a concentration of at least 500 ng/150 mm 2 in said wound.
Claim 6
Dependent Claim
22 words
The method of claim 3, said EGF being present at a concentration of at least 5000 ng/150 mm 2 in said wound.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1994-07-22 | 1995-01-21 | 1995-07-23 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1998-07-22 | 1999-01-21 | 1999-07-23 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2002-07-22 | 2003-01-21 | 2003-07-23 | $7700.00 | Window Closed / Lapsed |