US5019559A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Wound healing using PDGF and IGF-II
Assignee: Biomimetic Therapeutics LLC
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Filing: 1988-11-16
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Granted: 1991-05-28
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Expires: 2008-11-16
Abstract
Abstract Healing an external wound or regenerating bone of a mammal by administering to the mammal a composition containing purified platelet-derived growth factor and purified insulin-like growth factor II.
Inventors
- 👤 Harry N. Antoniades
- 👤 Samuel E. Lynch
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 19:23
CPC Classifications
C; C07; C07K; C07K14/00; C07K14/435; C07K14/475; C07K14/49; A; A61; A61K; A61K38/00; A61K38/16; A61K38/17; A61K38/22; A61K38/30
Claims Analysis
Total Claims: 15
Claim 1
Independent Claim
32 words
A method for healing an external wound of a mammal comprising applying to said wound a wound-healing amount of a composition comprising purified platelet-derived growth factor and purified insulin-like growth factor II.
Claim 2
Independent Claim
32 words
A method for healing an external wound of a mammal comprising applying to said wound a wound-healing amount of a composition comprising purified platelet-derived growth factor and purified insulin-like growth factor II.
Claim 3
Independent Claim
29 words
A method for regenerating bone of a mammal comprising administering to said mammal a wound-healing amount of a composition comprising purified platelet-derived growth factor and insulin-like growth factor II.
Claim 4
Independent Claim
29 words
A method for regenerating bone of a mammal comprising administering to said mammal a wound-healing amount of a composition comprising purified platelet-derived growth factor and insulin-like growth factor II.
Claim 5
Dependent Claim
33 words
The method of claim 1 or claim 2 wherein the weight to weight ratio of said platelet-derived growth factor to said insulin-like growth factor II in said composition is between 1:25 and 25:1.
Claim 6
Dependent Claim
13 words
The method of claim 3 wherein said ratio is between 1:10 and 10:1.
Claim 7
Dependent Claim
13 words
The method of claim 4 wherein said ratio is between 1:2 and 2:1.
Claim 8
Dependent Claim
28 words
A wound healing and bone regenerating composition comprising purified platelet-derived growth factor and purified insulin-like growth factor II, in a weight to weight ratio of 1:25 to 25:1.
Claim 9
Dependent Claim
28 words
A wound healing and bone regenerating composition comprising purified platelet-derived growth factor and purified insulin-like growth factor II, in a weight to weight ratio of 1:25 to 25:1.
Claim 10
Dependent Claim
13 words
The composition of claim 6 wherein said ratio is between 1:10 and 10:1.
Claim 11
Dependent Claim
13 words
The composition of claim 7 wherein said ratio is between 1:2 and 2:1.
Claim 12
Independent Claim
32 words
A method for preparing a composition for healing wounds, comprising mixing purified platelet-derived growth factor and purified insulin-like growth factor II in a weight to weight ratio of between 1:25 and 25:1.
Claim 13
Independent Claim
32 words
A method for preparing a composition for healing wounds, comprising mixing purified platelet-derived growth factor and purified insulin-like growth factor II in a weight to weight ratio of between 1:25 and 25:1.
Claim 14
Independent Claim
33 words
A method for promoting bone or periodontum growth comprising applying to said bone or periodontum a growth promoting amount of a composition comprising purified platelet-derived growth factor and purified insulin-like growth factor II.
Claim 15
Independent Claim
33 words
A method for promoting bone or periodontum growth comprising applying to said bone or periodontum a growth promoting amount of a composition comprising purified platelet-derived growth factor and purified insulin-like growth factor II.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1994-05-27 | 1994-11-26 | 1995-05-28 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1998-05-27 | 1998-11-26 | 1999-05-28 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2002-05-27 | 2002-11-26 | 2003-05-28 | $7700.00 | Window Closed / Lapsed |