US4974592A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Continuous on-line blood monitoring system
Assignee: AMERICAN SENSOR SYSTEMS Corp A CORP OF
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Filing: 1988-11-14
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Granted: 1990-12-04
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Expires: 2008-11-14
Abstract
Abstract A continuous on-line blood monitoring system for determining the ionic concentrations of certain ions within blood is disclosed. By use of a synchronized valving mechanism within the device, as well as locating the amplification electronics away from the sensor elements, a relatively small, but highly efficient analyzing system is provided.
Inventors
- 👤 Flavio S. C. Branco
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 15:34
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/483; G01N33/487; G01N33/49; A; A61; A61B; A61B5/00; A61B5/15; A61B5/150007; A61B5/150015; A61B5/15003; A61B5/150206; A61B5/150221; A61B5/150229; A61B5/150755; A61B5/155; G01N35/00; G01N35/08; A61B5/153; A61B5/157; G01N27/00; G01N27/26; G01N27/403; G01N27/414
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
152 words
A continuous on-line blood monitoring system for measuring ionic concentrations comprising: at least one ion concentration sensor device; a first feed line for receiving analyte connected to said sensor device; an analyte pinch/cylinder valve actuator operatively connected to said analyte feed line; a second feed line for receiving a solution to generate an ionic baseline connected to said sensor device; an ionic baseline pinch/cylinder valve actuator operatively connected to said second feed line; pumping means for activating and deactivating said analyte pinch/cylinder valve actuator and said ionic baseline pinch/cylinder valve actuator, said pumping means operatively connected to said analyte pinch/cylinder valve actuator and said baseline pinch/cylinder valve actuator; means for alternating the operation of said analyte pinch/cylinder valve actuator and said baseline pinch/cylinder valve actuator operatively connected to said pumping means; and means for amplifying and sending signals generated by the ionic concentration of said analyte operatively connected to said sensor device.
Claim 2
Dependent Claim
152 words
A continuous on-line blood monitoring system for measuring ionic concentrations comprising: at least one ion concentration sensor device; a first feed line for receiving analyte connected to said sensor device; an analyte pinch/cylinder valve actuator operatively connected to said analyte feed line; a second feed line for receiving a solution to generate an ionic baseline connected to said sensor device; an ionic baseline pinch/cylinder valve actuator operatively connected to said second feed line; pumping means for activating and deactivating said analyte pinch/cylinder valve actuator and said ionic baseline pinch/cylinder valve actuator, said pumping means operatively connected to said analyte pinch/cylinder valve actuator and said baseline pinch/cylinder valve actuator; means for alternating the operation of said analyte pinch/cylinder valve actuator and said baseline pinch/cylinder valve actuator operatively connected to said pumping means; and means for amplifying and sending signals generated by the ionic concentration of said analyte operatively connected to said sensor device.
Claim 3
Dependent Claim
12 words
The system of claim 1 wherein said sensor device is a ChemFET.
Claim 4
Dependent Claim
60 words
The system of claim 1 wherein said sensor device comprises a sensor plate having on one side thereof at least one sensor electrode having an active area covered with an ion selective membrane and connected to an extended area, said extended area in turn connected to a sensor terminal, and a reference electrode on the side opposite said sensor plate.
Claim 5
Dependent Claim
25 words
The system of claim 3 wherein said plate is of a glasslike material of low porosity, inert to both said analyte and a reference solutions.
Claim 6
Dependent Claim
11 words
The system of claim 4 wherein said sensor plate is quartz.
Claim 7
Dependent Claim
16 words
The system of claim 3 wherein said extended area is overlaid with a coating of silver/palladium.
Claim 8
Dependent Claim
14 words
The system of claim 3 wherein said active area is approximately two square millimeters.
Claim 9
Dependent Claim
15 words
The system of claim 3 wherein said selective membrane is selective to a specific ion.
Claim 10
Dependent Claim
30 words
The system of claim 3 wherein said reference electrode has in the central portion thereof an orifice having a diameter of between approximately 500 and 2,000 microns, preferably 1,000 microns.
Claim 11
Dependent Claim
14 words
The system of claim 9 wherein said reference electrode is of a noble metals.
Claim 12
Dependent Claim
25 words
The system of claim 1 wherein said means for amplifying and sending signals generated by the ionic concentration of said analyte is a fiberoptic cable.
References Cited (Backward Citations)
US4020830A
Cited
US4020830B1
Cited
US4280889A
Cited
US4238757A
Cited
US4314824A
Cited
US4130227A
Cited
US4218298A
Cited
US4180771A
Cited
US4269682A
Cited
US4172770A
Cited
US4399225A
Cited
US4352726A
Cited
US4267504A
Cited
US4315754A
Cited
US4322680A
Cited
US4534825A
Cited
US4397714A
Cited
US4502938A
Cited
US4636827A
Cited
US4514263A
Cited
US4411741A
Cited
US4488556A
Cited
US4641249A
Cited
US4589970A
Cited
US4508613A
Cited
US4657658A
Cited
WO1986005590A1
Cited
US4734184A
Cited
US4786394A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1993-12-03 | 1994-06-04 | 1994-12-04 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1997-12-03 | 1998-06-04 | 1998-12-04 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2001-12-03 | 2002-06-04 | 2002-12-04 | $7700.00 | Window Closed / Lapsed |