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US4488556A Expired / Lapsed US ⏱️ 0.0 years remaining

AC Mode operation of chemfet devices

Assignee: Ethicon Inc
•
Filing: 1982-06-03
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Granted: 1984-12-18
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Expires: 2002-06-03
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Abstract

Abstract A chemically sensitive field effect device has its chemically selective system exposed to the material being investigated. The device is driven by a time varying, typically sinusoidal, current source. A protected reference electrode is also in contact with the body under investigation, and is biased at a predetermined DC level relative to the chemically sensitive field effect device.

Inventors

  • 👤 Nelson Ho

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-25 17:40
CPC Classifications
G; G01; G01N; G01N27/00; G01N27/26; G01N27/403; G01N27/414; G01N27/4148

Claims Analysis

Total Claims: 10
Claim 1
Independent Claim 50 words
In combination, a chemically sensitive field effect transducer apparatus, means for coupling a sinusoidal drain-source potential to said transducer, and means for maintaining the gate of said transducer at a DC potential equal to the combination of a bias potential plus an electrochemically generated potential by a substance being sensed.
Claim 2
Dependent Claim 50 words
In combination, a chemically sensitive field effect transducer apparatus, means for coupling a sinusoidal drain-source potential to said transducer, and means for maintaining the gate of said transducer at a DC potential equal to the combination of a bias potential plus an electrochemically generated potential by a substance being sensed.
Claim 3
Dependent Claim 23 words
Apparatus as described in claim 1 and further comprising a reference electrode maintained at a predetermined DC bias relatve to the source electrode.
Claim 4
Dependent Claim 26 words
Apparatus as described in claim 2 wherein said means for generating generates a waveform having a frequency in the range between 10 Hz. and 1 MHz.
Claim 5
Dependent Claim 26 words
Apparatus as described in claim 3 wherein said means for generating generates a waveform having a frequency in the range between 100 kHz. and 200 kHz.
Claim 6
Dependent Claim 108 words
Apparatus for sensing the presence of a specified substance in a subject comprising: (a) a chemically sensitive field effect device having respective drain and source connections, a drain to source conduction path, and a chemically selective system overlying said path and modulating current therein in response to presence of said substance in said subject; (b) a reference electrode coupled to said subject; (c) means for generating and for coupling to said conduction path a sinusoidal time variant signal; and (d) means, coupled between said source and said reference electrode, for establishing a gate potential consisting of a bias potential plus the potential generated electrochemically by said specified substance.
Claim 7
Dependent Claim 108 words
Apparatus for sensing the presence of a specified substance in a subject comprising: (a) a chemically sensitive field effect device having respective drain and source connections, a drain to source conduction path, and a chemically selective system overlying said path and modulating current therein in response to presence of said substance in said subject; (b) a reference electrode coupled to said subject; (c) means for generating and for coupling to said conduction path a sinusoidal time variant signal; and (d) means, coupled between said source and said reference electrode, for establishing a gate potential consisting of a bias potential plus the potential generated electrochemically by said specified substance.
Claim 8
Dependent Claim 28 words
Apparatus as described in claim 5 wherein said means for generating comprises means for generating a substantially sinusoidal current waveform having a mean value of approximately zero volts.
Claim 9
Dependent Claim 26 words
Apparatus as described in claim 6 wherein said means for generating generates a waveform having a frequency in the range between 10 Hz. and 1 MHz.
Claim 10
Dependent Claim 26 words
Apparatus as described in claim 6 wherein said means for generating generates a waveform having a frequency in the range between 100 kHz. and 200 kHz.

References Cited (Backward Citations)

US4020830A Cited
US4020830B1 Cited
US4385274A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1987-12-18 1988-06-18 1988-12-18 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1991-12-18 1992-06-18 1992-12-18 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1995-12-18 1996-06-18 1996-12-18 $7700.00 Window Closed / Lapsed

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