Patent US4933145A successfully refreshed from Google Patents.
US4933145A
Expired / Lapsed
US
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Apparatus for inhibiting glycolysis in blood samples
Assignee: Terumo Corp
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Filing: 1988-06-03
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Granted: 1990-06-12
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Expires: 2008-06-03
Abstract
Abstract An article of manufacture comprising a blood-collection tube containing an acid such as citric acid in an amount effective to adjust the pH of the blood to be collected in the tube to a level between 5.0 to 7.0. The blood-collection tube may also contain NaF in an amount to produce a concentration thereof between 0.1 to 0.5 mg/ml of the blood.
Inventors
- 👤 Kazuo Uchida
- 👤 Shyoji Okuda
- 👤 Kiko Tanaka
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 14:34
CPC Classifications
C; C12; C12Q; C12Q1/00; C12Q1/54; G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/66; Y; Y10; Y10S; Y10S436/00; Y10S436/807; Y10S436/81; Y10S436/811; Y10S436/826; Y10T; Y10T436/00; Y10T436/10; Y10T436/108331; Y10T436/25; Y10T436/2525
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
60 words
An article of manufacture comprising a blood-collection tube containing an organic acid in an amount effective to adjust pH of blood to be collected in said tube to a level between 5.0 and 7.0 and to inhibit glycolysis of the blood, said organic acid being selected from the group consisting of citric acid, acetic acid, malonic acid and maleic acid.
Claim 2
Dependent Claim
60 words
An article of manufacture comprising a blood-collection tube containing an organic acid in an amount effective to adjust pH of blood to be collected in said tube to a level between 5.0 and 7.0 and to inhibit glycolysis of the blood, said organic acid being selected from the group consisting of citric acid, acetic acid, malonic acid and maleic acid.
Claim 3
Dependent Claim
35 words
The article of manufacture according to claim 1 wherein the acid is present in an amount effective to adjust the pH of the blood contained in said tube to a level between 5.0 and 6.8.
Claim 4
Dependent Claim
14 words
The article of manufacture according to claim 1 wherein said acid is citric acid.
Claim 5
Dependent Claim
27 words
The article of manufacture according to claim 3 wherein said citric acid is contained in an amount to produce a concentration between 1.0 and 5.0 mg/ml (blood).
Claim 6
Dependent Claim
32 words
The article of manufacture according to claim 4 wherein, in addition to citric acid, NaF is contained therein in an amount sufficient to provide a concentration between 0.1 and 0.5 mg/ml (blood).
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1993-06-11 | 1993-12-11 | 1994-06-12 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1997-06-11 | 1997-12-11 | 1998-06-12 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2001-06-11 | 2001-12-11 | 2002-06-12 | $7700.00 | Window Closed / Lapsed |