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US4880416A Expired / Lapsed US ⏱️ 0.0 years remaining

Dermal bandage and dermal preparation

Assignee: Nitto Denko Corp
•
Filing: 1988-10-31
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Granted: 1989-11-14
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Expires: 2008-10-31
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Abstract

Abstract A dermal bandage comprising a film-like adhesive material comprising at least one of polycarboxylic acids and polycarboxylic acid anhydrides, and a vinyl accetate polymer, and a dermal preparation comprising a film-like adhesive material containing drug, comprising at least one of polycarboxylic acids and polycarboxylic acid anhydride, and a vinyl acetate polymer are disclosed. The dermal bandage and dermal preparation exhibit strong adhesion of long duration only upon water absorption and is useful for prevention of running off of drugs applied to the skin or protection of affected parts of the skin.

Inventors

  • 👤 Tetsuo Horiuchi
  • 👤 Yuichi Inoue

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-04 20:09
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/70; A61K9/7023; A61K9/703; A61K9/7038; A61K9/7046; A61K9/7053; A61L; A61L15/00; A61L15/16; A61L15/42; A61L15/58; A61L15/585

Claims Analysis

Total Claims: 26
Claim 1
Independent Claim 97 words
A dermal bandage comprising a film-like adhesive material comprising: (a) vinyl acetate polymer and (b) at least one of polycarboxylic acid and polycarboxylic acid anhydride; wherein if a polycarboxylic acid is used, then said film-like adhesive material comprises 20% by weight or more of a --COOH group, and if a polycarboxylic acid anhydride is used, then said film-like adhesive material comprises 16% by weight ormore of a --CO--O--CO--group; and wherein a ratio of the polycarboxylic acid and/or polycarboxylic acid anhydride to the vinyl acetate polymer is in such a range that a value defined by formula: ##EQU2##
Claim 2
Dependent Claim 97 words
A dermal bandage comprising a film-like adhesive material comprising: (a) vinyl acetate polymer and (b) at least one of polycarboxylic acid and polycarboxylic acid anhydride; wherein if a polycarboxylic acid is used, then said film-like adhesive material comprises 20% by weight or more of a --COOH group, and if a polycarboxylic acid anhydride is used, then said film-like adhesive material comprises 16% by weight ormore of a --CO--O--CO--group; and wherein a ratio of the polycarboxylic acid and/or polycarboxylic acid anhydride to the vinyl acetate polymer is in such a range that a value defined by formula: ##EQU2##
Claim 3
Dependent Claim 41 words
A dermal bandage as in claim 1, wherein the film-like adhesive material contains at least one of polycarboxylic acid and polycarboxylic acid anhydride in an amount of 20 to 75% by weight based on the weight of the film-like adhesive material.
Claim 4
Dependent Claim 47 words
A dermal bandage as in claim 1, wherein said polycarboxylic acid and polycarboxylic acid anhydride are selected from the group consisting of an acrylic acid homopolymer, an acrylic acid copolymer, a methacrylic acid hompolymer, a methacrylic acid copolymer, a maleic anhydride homopolymer, and a maleic anhydride copolymer.
Claim 5
Dependent Claim 37 words
A dermal bandage as in claim 1, wherein said vinyl acetate polymer is selected from the group consisting of vinyl acetate homopolymer, a vinyl acetate copolymer with a vinyl monomer, and a partially saponified vinyl acetate homopolymer.
Claim 6
Dependent Claim 20 words
A dermal bandage as in claim 1, wherein said vinyl acetate polymer has a viscosity average molecular weight of 86,000-215,000.
Claim 7
Dependent Claim 20 words
A dermal bandage as in claim 1, wherein said adhesive film has a thickness of from 5 to 500 μm.
Claim 8
Dependent Claim 16 words
A dermal bandage as in claim 1, wherein said film-like adhesive material further contains a plasticizer.
Claim 9
Dependent Claim 13 words
A dermal bandage as in claim 7, wherein said plasticizer is polyethylene glycol.
Claim 10
Dependent Claim 21 words
A dermal bandage as in claim 1, wherein said film-like adhesive material further contains up to 50% by weight of water.
Claim 11
Dependent Claim 19 words
A dermal bandage as in claim 1, wherein said film-like adhesive material is laminated on a soft backing member.
Claim 12
Dependent Claim 39 words
A dermal bandage as in claim 10, wherein said backing member has a thickness of from 5 to 1,000 μm and a total thickness of the film-like adhesive material and the backing member is from 30 to 1,500 μm.
Claim 13
Dependent Claim 108 words
A dermal preparation comprising a film-like adhesive material comprising a mixture of: (a) vinyl acetate polymer, (b) at least one of polycarboxylic acid and polycarboxylic acid anhydride, and (c) a drum incorporated therein; wherein if polycarboxylic acid are used, then said film-like adhesive material comprises 20% by weight or more of a --COOH group, and if polycarboxylic acid anhydride are used, then said film-like adhesive material comprises 16% by weight or more of a --CO--O--CO--group; and wherein a ratio of the polycarboxylic acids and/or polycarboxylic acid anhydride to the vinyl acetate polymer is in such a range that a value defined by: ##EQU3## is from 15 to 55.
Claim 14
Dependent Claim 108 words
A dermal preparation comprising a film-like adhesive material comprising a mixture of: (a) vinyl acetate polymer, (b) at least one of polycarboxylic acid and polycarboxylic acid anhydride, and (c) a drum incorporated therein; wherein if polycarboxylic acid are used, then said film-like adhesive material comprises 20% by weight or more of a --COOH group, and if polycarboxylic acid anhydride are used, then said film-like adhesive material comprises 16% by weight or more of a --CO--O--CO--group; and wherein a ratio of the polycarboxylic acids and/or polycarboxylic acid anhydride to the vinyl acetate polymer is in such a range that a value defined by: ##EQU3## is from 15 to 55.
Claim 15
Dependent Claim 28 words
A dermal preparation as in claim 12, wherein the drug is solid or liquid at room temperature, which can be dissolved or dispersed in the film-like adhesive material.
Claim 16
Dependent Claim 28 words
A dermal preparation as in claim 12, wherein the amount of the drug is 0.001 to 30% by weight based on the weight of the film-like adhesive material.
Claim 17
Dependent Claim 41 words
A dermal preparation as in claim 12, wherein the film-like adhesive material contains at least one of polycarboxylic acid and polycarboxylic acid anhydride in an amount of 20 to 75% by weight based on the weight of the film-like adhesive material.
Claim 18
Dependent Claim 47 words
A dermal preparation as in claim 12, wherein said polycarboxylic acid and polycarboxylic acid anhydride are selected from the group consisting of an acrylic acid homopolymer, an acrylic acid copolymer, a methacrylic acid homopolymer, a methacrylic acid copolymer, a maleic anhydride homopolymer, and a maleic anhydride copolymer.
Claim 19
Dependent Claim 37 words
A dermal preparation as in claim 12, wherein said vinyl acetate polymer is selected from the group consisting of vinyl acetate homopolymer, a vinyl acetate copolymer with a vinyl monomer, and a partially saponified vinyl acetate homopolymer.
Claim 20
Dependent Claim 20 words
A dermal preparation as in claim 12, wherein said vinyl acetate polymer has a viscosity average molecular weight of 86,000-215,000.
Claim 21
Dependent Claim 20 words
A dermal preparation as in claim 12, wherein said adhesive film has a thickness of from 5 to 500 μm.
Claim 22
Dependent Claim 16 words
A dermal preparation as in claim 12, wherein said film-like adhesive material further contains a plasticizer.
Claim 23
Dependent Claim 13 words
A dermal preparation as in claim 20, wherein said plasticizer is polyethylene glycol.
Claim 24
Dependent Claim 21 words
A dermal preparation as in claim 12, wherein said film-like adhesive material further contains up to 50% by weight of water.
Claim 25
Dependent Claim 19 words
A dermal preparation as in claim 12, wherein said film-like adhesive material is laminated on a soft backing member.
Claim 26
Dependent Claim 39 words
A dermal preparation as in claim 23, wherein said backing member has a thickness of from 5 to 1,000 μm and a total thickness of the film-like adhesive material and the backing member is from 30 to 1,500 μm.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1992-11-13 1993-05-15 1993-11-14 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1996-11-13 1997-05-15 1997-11-14 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2000-11-13 2001-05-15 2001-11-14 $7700.00 Window Closed / Lapsed

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