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EP0223524A2 Expired / Lapsed EP ⏱️ 0.0 years remaining

Use of adhesive dermal bandages and dermal percutaneous preparations

Assignee: Nitto Denko Corp
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Filing: 1986-11-07
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Granted: —
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Expires: 2006-11-07
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Abstract

Abstract A composition is prepared by mixing usually in a mutual organic solvent, (a) 20-75wt% of polycarboxylic acid and/or anhydride, e.g. a (meth)acrylic polymer or maleic anhydride, and (b) a vinylacetate polymer, which can be a copolymer with a vinyl monomer, and preferably has a mol.wt. of 60,000 or more; plasticiser, water and/or a polyhydric alcohol may be included. A percutaneously absorbable pharmaceutical drug can be dissolved or dispersed in the composition. The composition is cast on a release surface and dried to make a film-like adhesive material of thickness 5 - 500 µm which can be used alone to cover a wound or to administer a drug if one has been incorporated. The film may be lamin­ated to a soft backing, e.g. a plastics film. The resultant dermal bandage or preparation for administration of a drug has good adhesion to the skin and high water-resistance.

Inventors

  • 👤 Tetsuo C/O Nitto Electric Horiuchi
  • 👤 Yuichi C/O Nitto Electric Inoue

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-11-05 05:25
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/70; A61K9/7023; A61K9/703; A61K9/7038; A61K9/7046; A61K9/7053; A61L; A61L15/00; A61L15/16; A61L15/42; A61L15/58; A61L15/585

Claims Analysis

Total Claims: 16
Claim 1
Independent Claim 26 words
A dermal bandage comprising a film-like adhesive material comprising a mixture of at least one polycarboxylic acid and/or polycarboxylic acid anhydride, and a vinyl acetate polymer.
Claim 2
Dependent Claim 26 words
A dermal bandage comprising a film-like adhesive material comprising a mixture of at least one polycarboxylic acid and/or polycarboxylic acid anhydride, and a vinyl acetate polymer.
Claim 3
Dependent Claim 24 words
A dermal preparation comprising a film-like adhesive material comprising a mixture as claimed in Claim 1 which also contains a percutaneously absorbable pharma­ceutical drug.
Claim 4
Dependent Claim 29 words
A dermal preparation as claimed in Claim 2, wherein the drug is solid or liquid at room temperature, and can be dissolved or dispersed in the film-like adhesive material.
Claim 5
Dependent Claim 31 words
A dermal preparation as claimed in Claim 2 or 3, wherein the amount of the drug is 0.001 to 30% by weight based on the weight of the film-like adhesive material.
Claim 6
Dependent Claim 45 words
A dermal bandage or preparation as claimed in any preceding claim, wherein the film-like adhesive material contains at least one of polycarboxylic acid and polycarboxy­lic acid anhydride in an amount of 20 to 75% by weight based on the weight of the film-like adhesive material.
Claim 7
Dependent Claim 43 words
A dermal bandage or preparation as claimed in any preceding claim, wherein said polycarboxylic acids and poly­carboxylic acid anhydrides are selected from an acrylic acid homopolymer, an acrylic acid copolymer, a methacrylic acid homopolymer, a methacrylic acid copolymer and a maleic anhydride copolymer.
Claim 8
Dependent Claim 40 words
A dermal bandage or preparation as claimed in any preceding claim, wherein said polycarboxylic acids contain 20% by weight or more of a -COOH group, and said polycar­boxylic acid anhydrides contain 16% by weight or more of a -CO-O-CO group.
Claim 9
Dependent Claim 36 words
A dermal bandage or preparation as claimed in any preceding claim, wherein said vinyl acetate polymer is a vinyl acetate homopolymer, a vinyl acetate copolymer with a vinyl monomer, or a partially saponified vinyl acetate homopolymer.
Claim 10
Dependent Claim 26 words
A dermal bandage or preparation as claimed in any preceding claim, wherein said vinyl acetate polymer has a viscosity average molecular weight of 60,000 or more.
Claim 11
Dependent Claim 47 words
A dermal bandage or preparation as claimed in any preceding claim, wherein the ratio of the polycarboxylic acids and/or polycarboxylic acid anhydrides to the vinyl acetate polymer is in such a range in the adhesive material that the expression of their weights: is from l5 to 55.
Claim 12
Dependent Claim 24 words
A dermal bandage or preparation as claimed in any preceding claim, wherein said adhesive film has a thickness of from 5 to 500 µm.
Claim 13
Dependent Claim 20 words
A dermal bandage or preparation as claimed in any preceding claim, wherein said film-like adhesive material further contains a plasticizer.
Claim 14
Dependent Claim 25 words
A dermal bandage or preparation as claimed in any preceding claim, wherein said film-like adhesive material further contains up to 50% by weight of water.
Claim 15
Dependent Claim 23 words
A dermal bandage or preparation as claimed in any preceding claim, wherein said film-like adhesive material is laminated on a soft backing member.
Claim 16
Dependent Claim 42 words
A dermal bandage or preparation as claimed in Claim 14, wherein said backing member has a thickness of from 5 to 1,000 µm and the total thickness of the film-like adhesive material and the backing member is from 30 to 1,500 µm.

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