EP0200508A2
Expired / Lapsed
EP
⏱️ 0.0 years remaining
Adhesive oral bandages and oral pharmaceutical preparations
Assignee: Sunstar Inc
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Filing: 1986-04-25
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Granted: —
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Expires: 2006-04-25
Abstract
Abstract A polycarboxylic acid or anhydride, e.g. acrylic or methacrylic acid polymer or maleic anhydride polymer, is mixed with a vinyl acetate polymer preferably of viscosity-average molecular weight of at least 60,000, and optionally with a base capable of neutralising the acid or anhydride, e.g. a salt of a metal or a weak acid. The mixture in a mutual organic or aqueous organic solvent is cast on a sheet base and dried and peeled off to form an oral bandage, which may include a soft film support. <??>The bandage shows strong adhesion for a period of at least 3 hours to the oral mucosa or teeth. <??>A topical drug can be incorporated in the adhesive bandage, to form an oral pharmaceutical preparation from which the drug is gradually released.
Inventors
- 👤 Yuichi Inoue
- 👤 Tetuo Horiuchi
- 👤 Kenji Hasegawa
- 👤 Koichi Nakashima
- 👤 Takashi Ysuyoshi
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-11-05 05:27
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0053; A61K9/006; A61L; A61L15/00; A61L15/16; A61L15/22; A61L15/225
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
29 words
An oral bandage comprising a soft adhesive film comprising a mixture of a polycarboxylic acid and/or a polycarboxylic acid anhydride and a vinyl acetate polymer in a compatible state.
Claim 2
Dependent Claim
29 words
An oral bandage comprising a soft adhesive film comprising a mixture of a polycarboxylic acid and/or a polycarboxylic acid anhydride and a vinyl acetate polymer in a compatible state.
Claim 3
Dependent Claim
39 words
An oral bandage as claimed in Claim 1, wherein the weight ratio of the polycarboxylic acid and/or polycarboxylic acid anhydride to vinyl acetate polymer is such that the value obtained from the following formula is from 15 to 45:
Claim 4
Dependent Claim
27 words
An oral bandage as claimed in Claim 1 or 2, wherein said vinyl acetate polymer has an average molecular weight determined by viscosity of at least 60,000.
Claim 5
Dependent Claim
37 words
An oral bandage as claimed in any preceding claim, wherein said polycarboxylic acid contains 20% by weight or more of a -COOH group and said polycarboxylic acid anhydride contains 16% by weight or more of a -CO-O-CO-group.
Claim 6
Dependent Claim
38 words
An oral bandage as claimed in any preceding claim, wherein said mixture in a compatible state is obtained by dissolving the polycarboxylic acid and/or polycarboxylic acid anhydride and the vinyl acetate polymer in a solvent common to both.
Claim 7
Dependent Claim
57 words
An oral bandage as claimed in Claim 5, wherein said solvent is selected from lower alcohols, mixtures of a lower alcohol in a larger proportion and a compatible organic solvent, mixtures of a lower alcohol in a larger proportion and water, and mixtures of a lower alcohol in a larger proportion, a compatible organic solvent and water.
Claim 8
Dependent Claim
30 words
An oral bandage as claimed in Claim 6, wherein said mixture of a lower alcohol and an organic solvent contains not more than 30% by weight of the organic solvent.
Claim 9
Dependent Claim
36 words
An oral bandage as claimed in Claim 6, wherein said mixture of a lower alcohol and water or of a lower alcohol, an organic solvent and water contains not mre than 30% by weight of water.
Claim 10
Dependent Claim
28 words
An oral bandage as claimed in any preceding claim, wherein said adhesive film further comprises a basic substance capable of neutralizing the polycarboxylic acid and/or polycarboxylic acid anhydride.
Claim 11
Dependent Claim
20 words
An oral bandage as claimed in Claim 9, wherein said basic substance is at least one of salt or base.
Claim 12
Dependent Claim
41 words
An oral bandage as claimed in Claim 10, wherein said basic substance is a monovalent metal salt or monovalent base and is present in an amount of from 0.03 to 02 equivalent based on the polycarboxylic acid and/or polycarboxylic acid anhydride.
Claim 13
Dependent Claim
19 words
An oral bandage as claimed in any preceding claim, wherein said oral bandage further comprises a soft film support.
Claim 14
Dependent Claim
19 words
An oral preparation comprising an oral bandage as defined in any preceding claim and a topical drug incorporated therein.
References Cited (Backward Citations)
No citation records indexed.
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