US4655768A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Bandage for sustained delivery of drugs
Assignee: Avery Dennison Corp
•
Filing: 1985-10-15
•
Granted: 1987-04-07
•
Expires: 2005-10-15
Abstract
Abstract A bandage for the transdermal or topical administration of a drug over an extended period of time comprising an impermeable backing sheet, a solid drug pellet on the backing sheet, and a layer of contact adhesive covering the pellet and backing sheet. In another form, the adhesive is carried by a web made of a non-woven or woven fabric. Control over the rate of dissolution of the solid drug can be achieved by varying the type of web fabric, the type of adhesive, and the thickness of the adhesive.
Inventors
- 👤 Nelda M. Marecki
- 👤 Gary A. Avalon
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 16:03
CPC Classifications
A; A61; A61M; A61M35/00; A61F; A61F13/00; A61F13/02; A61F13/0203; A61F13/0206; A61F13/0223; A61F13/0226; A61F13/0246; A61F13/0253; A61F13/0256
Claims Analysis
Total Claims: 33
Claim 1
Independent Claim
98 words
A bandage for transdermal or topical administration of a drug to the wearer thereof comprising: a liquid-impermeable backing sheet; a solid pure drug pellet constituted by compressed solid water-soluble drug powder positioned on said backing sheet; a layer of pressure-sensitive adhesive covering said drug pellet and backing sheet so that all upraised surfaces of said pellet are encased by said adhesive and said pellet makes no physical contact with the wearer during administration of the drug, whereby said adhesive remains in physical contact with the wearer and the drug is administered through said adhesive to the wearer's skin.
Claim 2
Dependent Claim
98 words
A bandage for transdermal or topical administration of a drug to the wearer thereof comprising: a liquid-impermeable backing sheet; a solid pure drug pellet constituted by compressed solid water-soluble drug powder positioned on said backing sheet; a layer of pressure-sensitive adhesive covering said drug pellet and backing sheet so that all upraised surfaces of said pellet are encased by said adhesive and said pellet makes no physical contact with the wearer during administration of the drug, whereby said adhesive remains in physical contact with the wearer and the drug is administered through said adhesive to the wearer's skin.
Claim 3
Dependent Claim
33 words
The bandage of claim 1 wherein said backing sheet comprises a material selected from the group consisting of aluminum foil, polyester, polypropylene, polyethylene, polyurethane film, and a laminate of aluminum foil and polyester.
Claim 4
Dependent Claim
17 words
The bandage of claim 2 wherein said backing sheet has a thickness between 6 and 50 microns.
Claim 5
Dependent Claim
31 words
The bandage of claim 1 wherein said drug pellet is substantially circular in configuration and has a diameter between 0.5 and 10 cm and a thickness between 5 and 1,000 microns.
Claim 6
Dependent Claim
15 words
The bandage of claim 4 wherein said drug pellet weighs between 1 and 1,000 mg.
Claim 7
Dependent Claim
25 words
The bandage of claim 1 wherein said pressure-sensitive adhesive comprises an adhesive selected from a group consisting of acrylic copolymer, styrene-butadiene-styrene, styrene-isoprene-styrene, and silicone polymer.
Claim 8
Dependent Claim
17 words
The bandage of claim 6 wherein said adhesive layer has a thickness between 10 and 150 microns.
Claim 9
Dependent Claim
14 words
The bandage of claim 6 wherein said pressure-sensitive adhesive has mineral oil incorporated therein.
Claim 10
Dependent Claim
107 words
A bandage for transdermal or topical administration of a drug to the wearer thereof comprising: a liquid-impermeable backing sheet; a solid pure drug pellet constituted by compressed solid water-soluble drug powder positioned on the inner surface of said backing sheet; and a carrier web coated with pressure-sensitive adhesive covering said pellet and backing sheet so that all upraised surfaces of said pellet are encased by said carrier web and said pellet makes no physical contact with the wearer during administration of the drug, whereby said adhesive coated web remains in physical contact with the wearer and the drug is administered through said adhesive to the wearer's skin.
Claim 11
Dependent Claim
107 words
A bandage for transdermal or topical administration of a drug to the wearer thereof comprising: a liquid-impermeable backing sheet; a solid pure drug pellet constituted by compressed solid water-soluble drug powder positioned on the inner surface of said backing sheet; and a carrier web coated with pressure-sensitive adhesive covering said pellet and backing sheet so that all upraised surfaces of said pellet are encased by said carrier web and said pellet makes no physical contact with the wearer during administration of the drug, whereby said adhesive coated web remains in physical contact with the wearer and the drug is administered through said adhesive to the wearer's skin.
Claim 12
Dependent Claim
26 words
The bandage of claim 9 wherein said carrier web comprises a non-woven fabric selected from a group consisting of nylon, polyethylene, polypropylene, rayon, cellulose-rayon, and polyester.
Claim 13
Dependent Claim
19 words
The bandage of claim 10 wherein said non-woven fabric has a weight between 1 and 100 mg/m 2 .
Claim 14
Dependent Claim
29 words
The bandage of claim 9 wherein said carrier web comprises a woven fabric of gauze or cellulosic materials having a weight of between 0.5 and 100 gm/m 2 .
Claim 15
Dependent Claim
19 words
The bandage of claim 9 wherein said carrier web is coated with said adhesive on both of its surfaces.
Claim 16
Dependent Claim
24 words
The bandage of claim 13 wherein said adhesive comprises an adhesive selected from the group consisting of acrylic copolymer, styrene-butadiene-styrene, styrene-isoprene-styrene, and silicone polymer.
Claim 17
Dependent Claim
47 words
The bandage of claim 14 wherein the coating of said adhesive on the skin contact surface of said carrier web has a thickness between 10 and 300 microns and the coating on the inner surface of said web has a thickness of between 10 and 300 microns.
Claim 18
Dependent Claim
31 words
The bandage of claim 9 wherein said drug pellet is substantially circular in configuration and has a diameter between 0.5 and 10 cm and a thickness between 5 and 1,000 microns.
Claim 19
Dependent Claim
15 words
The bandage of claim 16 wherein said drug pellet weighs between 1 and 1,000 mg.
Claim 20
Dependent Claim
20 words
The bandage of claim 15 wherein the adhesive on each of the surfaces of said carrier web comprises acrylic copolymer.
Claim 21
Dependent Claim
34 words
The bandage of claim 18 wherein the adhesive coating on the skin contact surface of said carrier web is approximately twice the thickness of the adhesive coating on the inner surface of said web.
Claim 22
Dependent Claim
32 words
The bandage of claim 15 wherein the adhesive on the skin contact surface of said carrier web comprises acrylic copolymer and the adhesive on the inner surface of said web comprises styrene-butadiene-styrene.
Claim 23
Dependent Claim
21 words
The bandage of claim 20 wherein said acrylate copolymer adhesive coating is approximately twice the thickness of said styrene-butadiene-styrene adhesive coating.
Claim 24
Dependent Claim
33 words
The bandage of claim 9 wherein said backing sheet comprises a material selected from the group consisting of aluminum foil, polyester, polypropylene, polyethylene, polyurethane film, and a laminate of aluminum foil and polyester.
Claim 25
Dependent Claim
89 words
A bandage for transdermal or topical administration of a drug to the wearer thereof comprising: a liquid-impermeable backing sheet; a layer of pressure-sensitive adhesive covering said backing sheet; and a solid pure drug pellet constituted by compressed water-soluble drug powder retained between said backing sheet and adhesive layer and encased by said adhesive so that said drug makes no physical contact with the wearer during administration thereof, whereby said adhesive remains in physical contact with the wearer and the drug is administered through said adhesive to the wearer's skin.
Claim 26
Dependent Claim
89 words
A bandage for transdermal or topical administration of a drug to the wearer thereof comprising: a liquid-impermeable backing sheet; a layer of pressure-sensitive adhesive covering said backing sheet; and a solid pure drug pellet constituted by compressed water-soluble drug powder retained between said backing sheet and adhesive layer and encased by said adhesive so that said drug makes no physical contact with the wearer during administration thereof, whereby said adhesive remains in physical contact with the wearer and the drug is administered through said adhesive to the wearer's skin.
Claim 27
Dependent Claim
33 words
The bandage of claim 23 wherein said backing sheet comprises a material selected from the group consisting of aluminum foil, polyester, polypropylene, polyethylene, polyurethane film, and a laminate of aluminum foil and polyester.
Claim 28
Dependent Claim
17 words
The bandage of claim 24 wnerein said backing sheet has a thickness between 6 and 50 microns.
Claim 29
Dependent Claim
31 words
The bandage of claim 23 wherein said drug pellet is substantially circular in configuration and has a diameter between 0.5 and 10 cm and a thickness between 5 and 1,000 microns.
Claim 30
Dependent Claim
15 words
The bandage of claim 26 wherein said drug pellet weighs between 1 and 1,000 mg.
Claim 31
Dependent Claim
25 words
The bandage of claim 23 wherein said pressure-sensitive adhesive comprises an adhesive selected from a group consisting of acrylic copolymer, styrene-butadiene-styrene, styrene-isoprene-styrene, and silicone polymer.
Claim 32
Dependent Claim
17 words
The bandage of claim 28 wherein said adhesive layer has a thickness between 10 and 150 microns.
Claim 33
Dependent Claim
14 words
The bandage of claim 28 wherein said pressure-sensitive adhesive has mineral oil incorporated therein.
References Cited (Backward Citations)
US3565075A
Cited
US3660323A
Cited
US3964482A
Cited
US3975570A
Cited
US3972995A
Cited
US4201211A
Cited
US4147831A
Cited
US4307717A
Cited
US4286592A
Cited
US4367732A
Cited
US4486193A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1990-04-06 | 1990-10-06 | 1991-04-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1994-04-06 | 1994-10-06 | 1995-04-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1998-04-06 | 1998-10-06 | 1999-04-07 | $7700.00 | Window Closed / Lapsed |