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US4846826A Expired / Lapsed US ⏱️ 0.0 years remaining

Method for treating ischemic conditions

Assignee: Alza Corp
•
Filing: 1986-11-21
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Granted: 1989-07-11
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Expires: 2006-11-21
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Abstract

Abstract A method is disclosed for treating an ischemic condition. The method comprises coadministering topically and internally a vasodilator to a patient having the condition for treating the condition.

Inventors

  • 👤 Jane Shaw
  • 👤 Robert M. Gale

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-28 20:32
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/70; A61K9/7023; A61K9/703; A61K9/7084; A61K31/00; A61K31/21

Claims Analysis

Total Claims: 6
Claim 1
Independent Claim 171 words
A method for treating angina in a patient having angina by transdermally and sublingually administering a drug to said patient for treating angina, wherein the method comprises: (a) placing on the dermis of patient afflicted with angina a medical bandage comprising: (1) a reservoir comprising a gel composition comprising: (i) an oil selected from the group consisting of an inorganic oil and an organic oil, (ii) a cellulosic means for gelling the oil, and (iii) a drug present in a therapeutically effective amount for treating angina; (2) a membrane adjacent to one surface of the reservoir, the membrane comprising a composition that aids in releasing the drug from the reservoir over time; (3) a backing member comprising a composition that is substantially impermeable to the passage of drug adjacent to the opposite surface of the reservoir, which backing contacts the membrane; (b) admitting sublingually into the patient a pharmaceutical dosage form comprising a drug useful for treating angina; and, (c) concomitently administering the drug transdermally for treating angina in the patient.
Claim 2
Independent Claim 171 words
A method for treating angina in a patient having angina by transdermally and sublingually administering a drug to said patient for treating angina, wherein the method comprises: (a) placing on the dermis of patient afflicted with angina a medical bandage comprising: (1) a reservoir comprising a gel composition comprising: (i) an oil selected from the group consisting of an inorganic oil and an organic oil, (ii) a cellulosic means for gelling the oil, and (iii) a drug present in a therapeutically effective amount for treating angina; (2) a membrane adjacent to one surface of the reservoir, the membrane comprising a composition that aids in releasing the drug from the reservoir over time; (3) a backing member comprising a composition that is substantially impermeable to the passage of drug adjacent to the opposite surface of the reservoir, which backing contacts the membrane; (b) admitting sublingually into the patient a pharmaceutical dosage form comprising a drug useful for treating angina; and, (c) concomitently administering the drug transdermally for treating angina in the patient.
Claim 3
Independent Claim 165 words
A method for treating angina in a patient having angina by transdermally and sublingually administering a drug for treating angina to said patient, which method comprises: (a) placing on the dermis of a patient afflicted with angina a medical bandage comprising: (1) a reservoir comprising a gel composition comprising: (i) an oil selected from the group consisting of an inorganic oil and an organic oil, (ii) polysaccharide means for gelling the oil, and (iii) a drug present in a therapeutically effective amount for treating angina; (2) a membrane adjacent to one surface of the reservoir, the membrane comprising a composition that aids in releasing the drug from the reservoir over time; (3) a backing member comprising a composition that is substantially impermeable to the passage of drug, and is in contacting relation with the membrane; (b) admitting sublingually into the patient a pharmaceutical dosage form comprising a drug useful for treating angina; and, (c) successively administering the drug transdermally for treating angina in the patient.
Claim 4
Independent Claim 165 words
A method for treating angina in a patient having angina by transdermally and sublingually administering a drug for treating angina to said patient, which method comprises: (a) placing on the dermis of a patient afflicted with angina a medical bandage comprising: (1) a reservoir comprising a gel composition comprising: (i) an oil selected from the group consisting of an inorganic oil and an organic oil, (ii) polysaccharide means for gelling the oil, and (iii) a drug present in a therapeutically effective amount for treating angina; (2) a membrane adjacent to one surface of the reservoir, the membrane comprising a composition that aids in releasing the drug from the reservoir over time; (3) a backing member comprising a composition that is substantially impermeable to the passage of drug, and is in contacting relation with the membrane; (b) admitting sublingually into the patient a pharmaceutical dosage form comprising a drug useful for treating angina; and, (c) successively administering the drug transdermally for treating angina in the patient.
Claim 5
Independent Claim 152 words
A method for treating angina in a patient having angina, which method comprises: (a) administering to the patient sublingually a dosage form comprising a beneficial drug useful for treating angina; (b) administering to the patient transdermally from a medical bandage a drug useful for treating angina, which bandage comprises: (1) a backing member comprising a composition that is substantially impermeable to the passage of drug; (2) a reservoir in contact with the backing member, the reservoir comprising: a gel composition comprising silicone fluid, silicon dioxide and a drug useful for treating angina dispersed through the gel composition; (3) a membrane positioned opposite the backing member and adjacent to the reservoir, the membrane comprising a composition that aids in releasing drug from the reservoir and is in contact with the backing member; and, (c) wherein the drug is administered sublingually and transdermally in a therapeutically effective amount to the patient for treating angina.
Claim 6
Independent Claim 152 words
A method for treating angina in a patient having angina, which method comprises: (a) administering to the patient sublingually a dosage form comprising a beneficial drug useful for treating angina; (b) administering to the patient transdermally from a medical bandage a drug useful for treating angina, which bandage comprises: (1) a backing member comprising a composition that is substantially impermeable to the passage of drug; (2) a reservoir in contact with the backing member, the reservoir comprising: a gel composition comprising silicone fluid, silicon dioxide and a drug useful for treating angina dispersed through the gel composition; (3) a membrane positioned opposite the backing member and adjacent to the reservoir, the membrane comprising a composition that aids in releasing drug from the reservoir and is in contact with the backing member; and, (c) wherein the drug is administered sublingually and transdermally in a therapeutically effective amount to the patient for treating angina.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1992-07-10 1993-01-09 1993-07-11 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1996-07-10 1997-01-09 1997-07-11 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2000-07-10 2001-01-09 2001-07-11 $7700.00 Window Closed / Lapsed

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